"Sitagliptin 100mg: Comprehensive Diabetes Care"

May 31, 2024

Introduction

ST-GLIPTIN 100 is a highly effective oral antidiabetic medication containing Sitagliptin Phosphate 100 mg, specially formulated to manage blood sugar levels in adults with Type 2 Diabetes Mellitus. As a selective DPP-4 (Dipeptidyl Peptidase-4) inhibitor, it enhances the body’s natural ability to regulate glucose without causing significant hypoglycemia or weight gain.

Composition Details

  • Active Ingredient: Sitagliptin Phosphate

  • Strength: Equivalent to Sitagliptin 100 mg

  • Dosage Form: Oral tablet

  • Therapeutic Class: Antidiabetic, DPP-4 Inhibitor

Mechanism of Action

Sitagliptin works by inhibiting the DPP-4 enzyme, which is responsible for the breakdown of incretin hormones. These hormones:

  • Increase insulin synthesis and release from pancreatic beta cells.

  • Decrease glucagon secretion from alpha cells. This dual action improves glycemic control, particularly postprandial glucose levels, without causing hypoglycemia when used alone.

Uses of Sitagliptin 100 mg (ST-GLIPTIN 100)

ST-GLIPTIN 100 is indicated for:

  • Type 2 Diabetes Mellitus: As monotherapy or in combination with other antidiabetic agents (e.g., metformin, sulfonylureas, SGLT2 inhibitors, or insulin) when diet and exercise alone do not provide adequate glycemic control.

 Note: It is not indicated for use in Type 1 Diabetes or for the treatment of diabetic ketoacidosis.

Dosage and Administration

  • Recommended Dose: 100 mg once daily with or without food.

  • Dose adjustment is recommended in patients with moderate to severe renal impairment or end-stage renal disease (ESRD).

  • Must be used as prescribed by a qualified healthcare professional.

Key Benefits of ST-GLIPTIN 100

  •  Helps lower both fasting and postprandial blood glucose
  •  Minimal risk of hypoglycemia
  •  Weight-neutral profile
  •  Convenient once-daily dosing
  •  Effective as monotherapy or add-on therapy
  •  Supports long-term glycemic control

Side Effects

Although generally well-tolerated, some patients may experience:

  • Headache

  • Nasopharyngitis (common cold symptoms)

  • Upper respiratory tract infections

  • Gastrointestinal disturbances (e.g., nausea, diarrhea)

  • Rare: Pancreatitis, allergic reactions, joint pain

Contact your doctor immediately if you experience symptoms of pancreatitis (persistent severe abdominal pain, sometimes radiating to the back) or hypersensitivity reactions.

Precautions and Warnings

  • Renal Impairment: Dose adjustment is required.

  • Pancreatitis Risk: Use with caution in patients with a history of pancreatitis.

  • Hypoglycemia Risk: When used with insulin or sulfonylureas, monitor for low blood sugar.

  • Pregnancy and Lactation: Use only if clearly needed under medical supervision.

  • Not for Pediatric Use.

Drug Interactions

  • Sitagliptin generally has a low risk of drug interactions.

  • Co-administration with insulin or insulin secretagogues increases the risk of hypoglycemia and should be monitored.

  • Inform your doctor of all medications you are taking before starting ST-GLIPTIN 100.

Storage Instructions

  • Store below 30°C in a dry place.

  • Protect from light and moisture.

  • Keep out of reach of children.

Why Choose ST-GLIPTIN 100 from Steris Healthcare?

  • WHO-GMP certified manufacturing
  • Clinically tested formulation
  • Affordable and widely available across India
  • High patient compliance due to once-daily dose
  • Backed by Steris Healthcare’s legacy of quality and trust

Frequently Asked Questions (FAQs)

Q1. What is ST-GLIPTIN 100 used for?
A: ST-GLIPTIN 100 is used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus.

Q2. Can ST-GLIPTIN 100 be taken with metformin?
A: Yes, it is commonly prescribed with metformin for enhanced glycemic control.

Q3. Is ST-GLIPTIN 100 safe in kidney patients?
A: Yes, but the dosage should be adjusted based on kidney function. Always consult your doctor.

Q4. Will ST-GLIPTIN 100 cause weight gain?
A: No, it is weight-neutral and does not contribute to weight gain.

Q5. Can I stop taking ST-GLIPTIN 100 if my sugar level becomes normal?
A: Never stop or change the dose without your doctor’s guidance. Diabetes requires long-term management.

Conclusion

ST-GLIPTIN 100 (Sitagliptin Phosphate 100 mg Tablet) is a modern, effective, and well-tolerated treatment option for patients managing Type 2 Diabetes Mellitus. Its convenient once-daily dosing and minimal side effects make it a preferred choice among healthcare professionals and patients alike.If you're looking for a trusted Sitagliptin brand in India, ST-GLIPTIN 100 from Steris Healthcare ensures reliability, safety, and affordability in diabetes care.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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