"Sitagliptin and Dapagliflozin: Comprehensive Diabetes Care"

ST- GLIPTIN DAPA 100/10 

Sitagliptin Phosphate and Dapagliflozin

Introduction

Sitagliptin Phosphate and Dapagliflozin is a combination medication used to manage type 2 diabetes effectively. This dual-action therapy helps to control blood sugar levels, enhance insulin sensitivity, and improve overall glucose metabolism. By combining the benefits of a dipeptidyl ST- GLIPTIN DAPA inhibitor and a sodium-glucose co-transporter 2 (SGLT2) inhibitor, this medication provides a comprehensive approach to diabetes care.

Mechanism of Action

Sitagliptin Phosphate

• Sitagliptin works by inhibiting the DPP-4 enzyme, which breaks down incretin hormones. Incretin hormones are crucial for regulating blood sugar levels, as they increase insulin synthesis and release from pancreatic beta cells while decreasing glucagon production. By preventing the breakdown of these hormones, Sitagliptin enhances their action, leading to better blood sugar control.

Dapagliflozin

• Dapagliflozin is an SGLT2 inhibitor that works by blocking the reabsorption of glucose in the kidneys. This action allows more glucose to be excreted through urine, thereby lowering blood sugar levels. Dapagliflozin also helps reduce body weight and blood pressure, contributing to improved overall health.

Uses

• Type 2 Diabetes Management: This combination is primarily used to manage type 2 diabetes in adults, helping to control blood sugar levels and prevent complications associated with diabetes.
• Cardiovascular and Renal Protection: The combination of Sitagliptin and Dapagliflozin can also provide cardiovascular and renal benefits, reducing the risk of heart failure and kidney disease.

Dosage and Administration

The typical dosage is one tablet of Sitagliptin Phosphate and Dapagliflozin taken once daily, with or without food. Regular blood sugar monitoring and follow-ups with your healthcare provider are essential to ensure the medication’s effectiveness.

Side Effects

Common side effects include:

• Nausea
• Diarrhea
• Dizziness
• Increased urination
• Hypoglycemia (low blood sugar)

Serious side effects may include:

• Pancreatitis (from Sitagliptin)
• Urinary tract infections (from Dapagliflozin)
• Allergic reactions

Precautions

• Kidney Function: Regular monitoring of kidney function is recommended, especially for patients with renal impairment.
• Liver Function: Patients with liver disease should use this combination cautiously.
• Hydration: Ensure adequate hydration to avoid dehydration, especially when using Dapagliflozin.

Conclusion

Sitagliptin Phosphate and Dapagliflozin offer a comprehensive approach to managing type 2 diabetes. By targeting different aspects of glucose metabolism, this combination helps maintain optimal blood sugar levels and improve overall health. Always follow your healthcare provider’s instructions and attend regular check-ups to ensure safe and effective treatment.Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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 EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

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