Rabeprazole (40mg),Domperidone (30mgSR) ..

Introduction

RABISTRUM DSR 40 is a widely used medication that contains a combination of Rabeprazole (40mg) and Domperidone (30mg SR). It is primarily prescribed for the treatment of gastroesophageal reflux disease (GERD), acid reflux, peptic ulcers, and functional dyspepsia. This medication works effectively by reducing stomach acid production and improving gastrointestinal motility, thereby providing relief from symptoms such as heartburn, bloating, nausea, and regurgitation.

Key Ingredients

Rabeprazole (40mg)

Rabeprazole is a proton pump inhibitor (PPI) that helps in reducing excessive stomach acid production by blocking the H+/K+ ATPase enzyme in the gastric parietal cells. It is highly effective in treating conditions like GERD, peptic ulcers, and Zollinger-Ellison syndrome.

Domperidone (30mg SR)

Domperidone is a prokinetic agent that works by blocking dopamine receptors in the upper digestive tract. It enhances gastric motility, prevents nausea and vomiting, and ensures the smooth movement of food through the digestive system.

How Does RABISTRUM DSR 40 Work?

Mechanism of Action

• Rabeprazole (40mg): Inhibits the proton pumps in the stomach lining, thereby decreasing gastric acid secretion and providing long-lasting relief from acid-related disorders.

• Domperidone (30mg SR): Acts on dopamine receptors, increasing gastric emptying and preventing reflux by strengthening the lower esophageal sphincter (LES).

Key Benefits of RABISTRUM DSR 40

1. Provides long-lasting relief from acid reflux and heartburn

2. Prevents and heals peptic ulcers

3. Enhances stomach emptying and reduces bloating

4. Relieves nausea and vomiting caused by delayed gastric emptying

5. Prevents the recurrence of GERD symptoms

6. Effective in the management of Zollinger-Ellison syndrome

7. Improves digestion and reduces discomfort after meals

8. Minimizes regurgitation and chronic belching

Uses of RABISTRUM DSR 40

1. Gastroesophageal Reflux Disease (GERD)

GERD is a chronic condition where stomach acid flows back into the esophagus, causing symptoms like heartburn, regurgitation, and difficulty swallowing. RABISTRUM DSR 40 effectively manages GERD by reducing acid secretion and improving gastric motility.

2. Peptic Ulcers

Peptic ulcers occur due to excessive stomach acid and bacterial infections like H. pylori. Rabeprazole (40mg) plays a vital role in healing ulcers by reducing acid levels, while Domperidone (30mg SR) ensures proper digestion and prevents discomfort.

3. Functional Dyspepsia

Also known as indigestion, functional dyspepsia causes bloating, stomach pain, and nausea. RABISTRUM DSR 40 enhances gastric motility, making it easier for food to move through the digestive tract.

4. Zollinger-Ellison Syndrome

A rare condition where the stomach produces excessive acid, Zollinger-Ellison syndrome can lead to severe ulcers. Rabeprazole (40mg) helps control excessive acid secretion, providing relief from symptoms.

Dosage and Administration

• Recommended Dose: One capsule of RABISTRUM DSR 40 per day, preferably before breakfast.

• Mode of Administration: Take the capsule on an empty stomach with a glass of water.

• Do Not Chew or Crush: Swallow the capsule whole for proper drug absorption.

• Missed Dose: Take it as soon as you remember, but do not double the dose if it is close to the next scheduled dose.

Side Effects of RABISTRUM DSR 40

While RABISTRUM DSR 40 is generally well-tolerated, some individuals may experience mild to moderate side effects, including:

1. Headache and dizziness

2. Nausea and vomiting

3. Diarrhea or constipation

4. Abdominal pain or bloating

5. Dry mouth

6. Flatulence

7. Fatigue or drowsiness

8. Skin rash or itching (rare cases)

If any severe side effects occur, such as severe allergic reactions, irregular heartbeat, or difficulty breathing, seek medical attention immediately.

Precautions and Warnings

Who Should Avoid RABISTRUM DSR 40?

• Patients allergic to Rabeprazole or Domperidone

• Individuals with severe liver or kidney disease

• Patients with cardiac conditions (as Domperidone may affect heart rhythm)

• Those suffering from gastrointestinal bleeding or obstruction

• Pregnant and breastfeeding women should consult a doctor before use.

Drug Interactions

RABISTRUM DSR 40 may interact with other medications, such as:

• Antacids and H2-receptor blockers (reducing effectiveness)

• Antibiotics like Clarithromycin and Amoxicillin (used in H. pylori treatment)

• Blood thinners (Warfarin) (increased bleeding risk)

• Antifungal drugs (Ketoconazole, Itraconazole) (absorption issues)

• Antidepressants and Parkinson’s medications (interaction with Domperidone)

Price of RABISTRUM DSR 40 in India

The price of RABISTRUM DSR 40 varies depending on the manufacturer and location. On average, a strip of 10 capsules costs around ₹150-₹250 in India. Prices may fluctuate based on availability and discounts offered by pharmacies.

Alternatives to RABISTRUM DSR 40

Some alternative brands with similar compositions include:

1. OXYBUTYRIN 2.5

2. Rabicip DSR

3. Rablet DSR

4. Domstal-RD

5. Rabonik DSR

Conclusion

RABISTRUM DSR 40, a combination of Rabeprazole (40mg) and Domperidone (30mg SR), is a highly effective medication for treating acid reflux, GERD, peptic ulcers, and functional dyspepsia. It offers long-lasting relief from heartburn, bloating, and regurgitation while promoting healthy digestion. With proper dosage and precautions, it serves as a reliable solution for acid-related disorders.

If you experience severe side effects or have underlying medical conditions, consult a doctor before using RABISTRUM DSR 40. Alternative options like OXYBUTYRIN 2.5 are available for those requiring similar treatment.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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