Rifaximin 400 mg Uses , Benefits & Dosage | Rifaximin Tablet Guide

rifaximin 400 mg uses

RIFAXIKEM 400 is a powerful, gut-targeted antibiotic that contains rifaximin 400 mg, a broad-spectrum agent widely recommended for treating various gastrointestinal infections. If you're looking for detailed, up-to-date information about rifaximin 400 mg uses, its benefits, effectiveness, dosage guidelines, and affordability, this guide will walk you through everything you need to know.

This formulation, offered by Steris Healthcare, is manufactured with globally compliant standards and trusted by medical professionals across India for its safety, efficacy, and high-quality formulation.

What is RIFAXIKEM-400?

RIFAXIKEM-400 is an oral antibiotic containing rifaximin 400 mg as the active ingredient. It is specifically designed to act within the intestines without being absorbed into the bloodstream. This localized action makes rifaximin highly effective in managing intestinal infections and complications associated with liver disorders and irritable bowel syndromes. Unlike systemic antibiotics, rifaximin 400 does not disrupt the body’s overall bacterial balance, and it has a significantly lower risk of causing resistance.

rifaximin 400 mg Uses

Rifaximin 400 mg is commonly prescribed for a range of gastrointestinal and hepatic conditions. Its effectiveness in both acute and chronic bacterial infections of the gut makes it an important part of modern treatment protocols.

One of the primary rifaximin 400 mg uses is in the treatment of traveler’s diarrhea, especially cases caused by non-invasive strains of Escherichia coli. It provides rapid relief from symptoms like watery stools, bloating, abdominal cramps, and urgency.

Patients with chronic liver disease, particularly those at risk of hepatic encephalopathy, are also prescribed rifaximin 400 mg to reduce the bacterial load that produces harmful toxins such as ammonia. This helps prevent the recurrence of cognitive issues, confusion, and drowsiness associated with liver-related brain dysfunction.

In recent years, rifaximin 400 mg has gained prominence in the treatment of IBS-D (Irritable Bowel Syndrome with Diarrhea). Short-term courses of the medication help regulate stool frequency and relieve abdominal discomfort.

It is also used off-label in the management of SIBO (Small Intestinal Bacterial Overgrowth), a condition that causes persistent gas, bloating, and digestive irregularities due to excessive bacterial presence in the small intestine.

How Does rifaximin 400 mg Work?

Rifaximin works by binding to and inhibiting bacterial RNA polymerase, an enzyme crucial for bacterial replication. By blocking this enzyme, rifaximin 400 mg prevents bacteria from multiplying, which in turn reduces the symptoms of infection. The unique feature of rifaximin is its minimal absorption — it remains in the gut, acting directly at the site of infection, which reduces systemic side effects and improves tolerability in both short and long-term use.

Dosage and Administration

Rifaximin 400 is usually prescribed in different dosages based on the condition. For traveler’s diarrhea, the typical regimen is 400 mg three times a day for three days. For hepatic encephalopathy, it may be prescribed as 400 mg two or three times daily, depending on clinical evaluation. For IBS-D or SIBO, a common recommendation is 400 mg two to three times a day for 10–14 days.

It is essential to complete the full course as advised by a healthcare professional, even if symptoms improve earlier, to ensure complete elimination of harmful bacteria and avoid recurrence.

Side Effects of rifaximin 400

Most individuals tolerate rifaximin well due to its gut-localized action. However, some may experience mild side effects like bloating, nausea, headache, dizziness, abdominal pain, or flatulence. These side effects are usually temporary and subside as the body adjusts to the medication. In rare cases, allergic reactions such as rash, itching, or swelling may occur. Patients should immediately consult a physician if any unusual symptoms persist or worsen.

Who Should Avoid Rifaximin 400

Rifaximin 400 mg is not recommended in cases of fever or bloody diarrhea, as these symptoms may suggest invasive bacterial infections that require different treatment. Individuals allergic to rifamycin-class antibiotics should also avoid this medication. Patients with gastrointestinal obstruction or severe liver impairment should use the drug only under strict medical supervision. It is advisable to consult a healthcare provider before starting rifaximin during pregnancy or breastfeeding.

Drug Interactions

Although rifaximin has minimal systemic absorption, interactions may still occur with certain medications. These include cyclosporine, warfarin, oral contraceptives, antifungal agents, and antiviral medications. It's important to disclose all current medications and health conditions to your doctor before starting rifaximin 400 mg.

rifaximin 400 mg Price in India

If you’re concerned about cost, the rifaximin 400 mg price varies by location and brand. However, RIFAXIKEM-400 by Steris Healthcare is one of the most competitively priced and high-quality options available in the Indian market. The product is affordably positioned to ensure access for long-term treatment plans without burdening the patient financially.

Why Steris Healthcare is Better

Steris Healthcare is widely regarded as one of India’s fastest-growing and most reliable pharmaceutical brands. The company follows WHO-GMP certified practices, and every batch is produced with stringent quality controls in state-of-the-art facilities. The company’s core philosophy is to combine scientific research, affordability, and patient safety — a rare combination that places it ahead of other pharmaceutical brands.

The availability of Steris products across India, from metro cities to rural markets, makes it a preferred choice for both doctors and patients. In addition, the brand offers direct access through its official website for convenience and trust. With Steris, you don’t just get medicine—you get commitment, consistency, and care.

Where to Buy RIFAXIKEM 400

RIFAXIKEM-400 is available at major pharmacy chains, hospital dispensaries, and reputable local medical stores across India. For those who prefer the convenience of online ordering with guaranteed authenticity, the best place to purchase is the official website of Steris Healthcare:

Visit: www.sterisonline.com

This ensures that you get genuine, safe, and affordable medicine delivered directly to your doorstep.

FAQs on RIFAXIKEM 400

What are the main rifaximin 400 mg uses?
Rifaximin 400 is used to treat traveler’s diarrhea, hepatic encephalopathy, IBS-D, and small intestinal bacterial overgrowth.

How fast does rifaximin 400 mg work?
Many patients experience symptom improvement within 24 to 48 hours after starting therapy, especially in cases of diarrhea.

Is rifaximin 400 safe for repeated use?
Yes, when prescribed by a doctor, it is safe for cyclic or repeat use in chronic conditions like IBS-D or HE.

What is the rifaximin 400 mg price range?
Prices may vary depending on location, but RIFAXIKEM-400 from Steris Healthcare is among the most affordable rifaximin brands in India.

Is a prescription required for RIFAXIKEM-400?
Yes, rifaximin is a prescription-only medicine and should be taken under medical supervision.

Conclusion

RIFAXIKEM-400 offers a highly effective, gut-focused solution for a wide range of gastrointestinal infections and liver-associated conditions. With minimal systemic absorption and proven clinical outcomes, rifaximin 400 mg uses is one of the safest antibiotics available for intestinal treatment. Backed by the manufacturing excellence of Steris Healthcare, RIFAXIKEM-400 ensures patients receive world-class treatment at an affordable cost.

For trusted quality and nationwide accessibility, Steris Healthcare continues to lead the way. Choose RIFAXIKEM-400 today to experience reliable relief and professional pharmaceutical care.