Sacubitril and Valsartan Tablets – Uses, Dosage, Side Effects & Benefits

If you're managing chronic heart failure, every heartbeat matters. The right medication can reduce hospital visits, improve your quality of life, and help you live longer. One such modern therapy is SACUSMART 200, which contains sacubitril and valsartan tablets in the strength of 97 mg + 103 mg—a clinically effective and widely prescribed combination that offers powerful benefits for patients with Heart Failure with Reduced Ejection Fraction (HFrEF).

Formulated by Steris Healthcare, SACUSMART 200 is designed to improve heart function, lower blood pressure, and reduce the strain on your heart—making it a smart and proactive choice for managing your condition.

What Are Sacubitril and Valsartan Tablets?

Sacubitril and valsartan tablets combine two active components that work together to treat heart failure more effectively than older therapies like ACE inhibitors alone.

 Sacubitril

A neprilysin inhibitor that increases levels of natural peptides in the body, helping to widen blood vessels, reduce fluid buildup, and improve heart efficiency.

 Valsartan

An angiotensin II receptor blocker (ARB) that lowers blood pressure, reduces strain on the heart, and prevents further cardiac damage.

Together, this combination—commonly known as sacubitril valsartan—offers dual benefits: preventing the progression of heart failure and improving survival rates in affected patients.

Sacubitril and Valsartan Tablets Uses

If you're wondering about sacubitril valsartan tablets uses, here's what it helps treat:

• Chronic Heart Failure (HFrEF) – to improve heart function and reduce symptoms

• To reduce risk of cardiovascular death and hospitalizations in patients with heart failure

• Improving exercise tolerance and energy levels

• As a replacement for ACE inhibitors or ARBs in some heart failure treatment plans

This therapy has been proven in large clinical trials (like the PARADIGM-HF study) to be more effective than standard ACE inhibitors in preventing heart failure-related complications.

How SACUSMART 200 Works

SACUSMART 200 delivers 97 mg of sacubitril and 103 mg of valsartan per tablet, offering a once or twice-daily solution for continuous heart protection.

Here’s how it helps:

• Reduces high blood pressure by relaxing blood vessels

• Lowers fluid retention to reduce swelling and lung congestion

• Supports the heart muscle to pump more effectively

• Reduces the chance of sudden cardiac events or hospitalization

By combining sacubitril and valsartan, SACUSMART 200 provides comprehensive cardiac support tailored for long-term management.

Dosage

• Starting dose usually begins at 24 mg sacubitril + 26 mg valsartan twice daily for patients not previously on ACE inhibitors or ARBs or on low doses of these drugs.

• For those on moderate to high doses of ACE inhibitors or ARBs, a starting dose of 49 mg sacubitril + 51 mg valsartan twice daily is common.

• The dose may then be increased every 2 to 4 weeks to a target maintenance dose of 97 mg sacubitril + 103 mg valsartan twice daily as tolerated by the patient.

Patients with kidney or liver impairment may require lower starting doses.

Common Side Effects

• Low blood pressure (hypotension)

• Dizziness

• Cough

• Increased potassium levels in the blood

• Kidney function changes including increased creatinine

• Fatigue and headache

• Rare cases of angioedema (swelling under the skin), which requires immediate medical attention.

Why Choose SACUSMART 200 by Steris Healthcare?

Steris Healthcare is known for affordable, high-quality, and innovative formulations. With SACUSMART 200, you benefit from:

• ✔️ WHO-GMP certified manufacturing quality

• ✔️ Accurate dosing for optimal efficacy

• ✔️ Trusted by cardiologists and general physicians

• ✔️ Cost-effective treatment for long-term use

• ✔️ Widely available across India

Steris Healthcare is committed to improving chronic care outcomes through trusted pharmaceutical excellence.

Frequently Asked Questions

1. What is the purpose of sacubitril and valsartan tablets?

They are used to treat heart failure with reduced ejection fraction (HFrEF) by improving heart function, lowering blood pressure, and reducing the risk of hospitalizations and heart-related death.

2. Can I take sacubitril valsartan with other heart medications?

Yes, but always under the supervision of your doctor. It is often combined with beta-blockers and diuretics.

3. Are there any side effects?

Possible side effects include:

• Low blood pressure (dizziness or fainting)

• High potassium levels

• Kidney function changes

• Fatigue
  Always report any symptoms to your doctor.

4. Can it replace my current blood pressure medication?

In many heart failure cases, sacubitril and valsartan replace ACE inhibitors or other ARBs for better long-term results. Your doctor will guide you based on your heart condition.

5. How long do I need to take SACUSMART 200?

Heart failure is a chronic condition, so long-term use is often necessary. Your doctor will regularly monitor your progress.

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