SACUBRIGHT 100 Mg Tablet : Uses, Side Effects, Dosage, Mechanism of Action...

May 17, 2024

SACUBRIGHT 100 Mg 

Sacubitril (49mg) and Valsartan (51mg)

SACUBRIGHT 100 is a combination medication containing Sacubitril (49mg) and Valsartan (51mg). It is primarily used for the treatment of heart failure to reduce the risk of cardiovascular death and hospitalization. The synergistic action of Sacubitril, a neprilysin inhibitor, and Valsartan, an angiotensin II receptor blocker (ARB), provides a comprehensive approach to managing heart failure.

Composition

  • Sacubitril: 49mg
  • Valsartan: 51mg

Mechanism of Action

Sacubitril

This inhibition leads to increased levels of these peptides, resulting in vasodilation, natriuresis, and diuresis, which help to alleviate the symptoms of heart failure.

Valsartan

Valsartan blocks the angiotensin II receptor, preventing angiotensin II from exerting its vasoconstrictive and aldosterone-secreting effects. This blockade leads to reduced blood pressure, decreased workload on the heart, and improved cardiac function.

Indications

SACUBRIGHT 100 is indicated for:

  • Reducing the risk of cardiovascular death and hospitalization due to heart failure.

Dosage and Administration

  • Dosage may be adjusted based on patient response and tolerability.
  • It should be taken with or without food.

Benefits

  • Improved Heart Function: Enhances cardiac output and reduces symptoms of heart failure.
  • Reduced Hospitalizations: Lowers the risk of hospitalization due to worsening heart failure.
  • Enhanced Quality of Life: Patients experience better management of heart failure symptoms, leading to improved daily functioning and well-being.

Side Effects

Common side effects of SACUBRIGHT 100 may include:

  • Hypotension
  • Hyperkalemia
  • Cough
  • Dizziness
  • Renal impairment

Precautions

  • Monitoring: Regular monitoring of blood pressure, renal function, and potassium levels is essential.
  • Pregnancy: Not recommended for use during pregnancy due to potential harm to the fetus.
  • Interactions: Avoid concurrent use with ACE inhibitors, as this increases the risk of angioedema.

Conclusion

SACUBRIGHT 100 (Sacubitril 49mg, Valsartan 51mg) is a potent combination therapy for managing heart failure. Its dual mechanism of action offers significant benefits in reducing the risk of cardiovascular events and improving the overall quality of life for patients with heart failure. Regular monitoring and adherence to prescribed dosage are crucial for achieving optimal therapeutic outcomes. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

CALL/WHATSAPP: 7877551268, 7849827488

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