SACUBRIGHT 200 Mg : Uses, Dosage, and Safety….

SACUBRIGHT 200 Mg

Sacubitril (97mg), Valsartan (103mg)

SACUBRIGHT 200 is a combination medication containing Sacubitril (97mg) and Valsartan (103mg). It belongs to the class of angiotensin receptor neprilysin inhibitors (ARNIs) and is used in the management of heart failure with reduced ejection fraction (HFrEF). This guide provides an in-depth exploration of its uses, dosage, price, side effects, composition, and other essential information.

Uses of SACUBRIGHT 200

1. Heart Failure: SACUBRIGHT 200 is indicated for the treatment of chronic heart failure with reduced ejection fraction (HFrEF) in adult patients to reduce the risk of cardiovascular death and hospitalization for heart failure.
2. Neprilysin Inhibition: Sacubitril, a neprilysin inhibitor, works by enhancing natriuretic peptides, which are beneficial in heart failure management.
3. Angiotensin Receptor Blockade: Valsartan, an angiotensin receptor blocker (ARB), helps in vasodilation and blood pressure control, complementing the effects of sacubitril.

Dosage of SACUBRIGHT 200 The dosage of SACUBRIGHT 200 is individualized based on the patient's medical history, current medications, renal function, and response to treatment. A typical dosage regimen may include:

• Initial dose: SACUBRIGHT 200 (Sacubitril 97mg, Valsartan 103mg) twice daily.
• Titration: The dosage may be increased as tolerated, usually at 2- to 4-week intervals, to achieve target doses based on clinical assessment.

It is crucial to follow the prescribed dosage and titration schedule as guided by the healthcare provider for optimal therapeutic outcomes.

Price of SACUBRIGHT 200 The price of SACUBRIGHT 200 can vary depending on factors such as the brand, dosage strength, and the quantity of tablets in a pack. As a combination medication, it may be priced higher than individual components but is often cost-effective compared to separate prescriptions of Sacubitril and Valsartan.

Side Effects of SACUBRIGHT 200 While SACUBRIGHT 200 is generally well-tolerated, some individuals may experience mild to moderate side effects. These side effects may include:

1. Hypotension: As with other ARNI and ARB medications, SACUBRIGHT 200 may cause low blood pressure, especially during initial titration or in patients with volume depletion.
2. Hyperkalemia: Valsartan component may lead to elevated potassium levels, particularly in patients with renal impairment or those taking potassium-sparing diuretics.
3. Renal Impairment: SACUBRIGHT 200 may worsen renal function, especially in patients with pre-existing renal disease or those taking other nephrotoxic medications.
4. Cough: A dry, persistent cough may occur due to the ACE inhibitor component of sacubitril, although less commonly observed than with standalone ACE inhibitors.

It is essential to monitor for these side effects and adjust treatment accordingly under the guidance of a healthcare professional.

Composition of SACUBRIGHT 200

Each SACUBRIGHT 200 tablet contains Sacubitril 97mg and Valsartan 103mg as active ingredients. The combination of these agents provides dual mechanisms of action, targeting neurohormonal pathways involved in heart failure pathophysiology.

Precautions and Warnings

• SACUBRIGHT 200 should not be used in patients with a history of angioedema related to ACE inhibitors or ARBs.
• Patients should be monitored for signs of hypotension, electrolyte imbalances, and renal function during treatment with SACUBRIGHT 200.
• Avoid concomitant use of SACUBRIGHT 200 with other ARBs, ACE inhibitors, or aliskiren due to the risk of dual renin-angiotensin-aldosterone system (RAAS) blockade.
• Use with caution in patients with impaired hepatic function, as the medication may require dosage adjustments.

Conclusion

SACUBRIGHT 200, combining Sacubitril and Valsartan, represents a significant advancement in the management of heart failure with reduced ejection fraction. Its dual mechanism of action offers comprehensive benefits in reducing cardiovascular morbidity and mortality. However, close monitoring for side effects, adherence to dosage guidelines, and regular follow-up with healthcare providers are essential for safe and effective use of SACUBRIGHT 200 in heart failure patients. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. Gynecology, Pediatrics, Dental care, and Dermatology. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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