SAVELINER 400 & Sevelamer (400mg).:Tablet- Uses, Side Effects, Dosage, Mechanism of action...

SAVELINER 400 

Sevelamer (400mg)

 SAVELINER 400 contains Sevelamer (400 mg), which is a medication primarily used to control hyperphosphatemia in patients with chronic kidney disease (CKD) who are on dialysis. Hyperphosphatemia is a condition characterized by elevated phosphate levels in the blood, which can lead to severe complications such as bone and cardiovascular diseases. SAVELINER 400, containing Sevelamer 400mg, helps manage phosphate levels effectively, thereby reducing associated health risks.

Uses of SAVELINER 400

Management of Hyperphosphatemia

The primary use of SAVELINER 400 is to manage hyperphosphatemia in CKD patients undergoing dialysis. High phosphate levels can cause calcium to be deposited in blood vessels and other tissues, leading to cardiovascular problems and bone disorders.

Cardiovascular Protection

By controlling phosphate levels, SAVELINER 400 also helps protect against cardiovascular complications. Excess phosphate can lead to vascular calcification, a significant risk factor for heart disease. Regular use of Sevelamer reduces this risk, promoting better cardiovascular health in CKD patients.

Bone Health

High phosphate levels can disrupt the balance of calcium and phosphate in the body, leading to weakened bones and increased fracture risk. SAVELINER 400 helps maintain this balance, thereby supporting bone health and reducing the likelihood of bone-related issues.

Dosage and Administration

Recommended Dosage

The recommended starting dose of SAVELINER 400 varies based on serum phosphate levels. For adults, the typical starting dose is one to two tablets taken three times a day with meals. The dosage may be adjusted by healthcare providers based on the patient's phosphate levels and individual response to treatment.

Administration

Consistency in taking the medication with every meal is crucial for optimal phosphate control.

Mechanism of Action

Sevelamer, the active ingredient in SAVELINER 400, is a non-absorbed phosphate binder. It works by binding dietary phosphate in the gastrointestinal tract, forming an insoluble complex that is excreted in the feces. This process reduces the amount of phosphate absorbed into the bloodstream, thereby lowering serum phosphate levels.

Side Effects

Common Side Effects

While SAVELINER 400 is generally well-tolerated, some patients may experience side effects, including:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, indigestion, and abdominal pain.
• Bloating and Gas: Some patients may experience increased bloating and gas.

Serious Side Effects

Serious side effects are rare but can occur. These include:

• Bowel Obstruction: Symptoms include severe abdominal pain, vomiting, and inability to pass stool or gas. Immediate medical attention is required.

Patients are advised to report any persistent or severe side effects to their healthcare provider promptly.

Precautions and Interactions

Precautions

Before starting SAVELINER 400, patients should inform their healthcare provider of any existing medical conditions, particularly:

• Bowel Obstructions: Patients with a history of bowel obstructions should use Sevelamer with caution.
• Swallowing Disorders: Those with difficulty swallowing should be monitored closely due to the risk of esophageal obstruction.

Drug Interactions

SAVELINER 400 may interact with other medications. Some notable interactions include:

• Ciprofloxacin: Sevelamer can reduce the absorption of ciprofloxacin, an antibiotic.
• Antiarrhythmic Medications: The absorption of certain antiarrhythmics may be affected. Monitoring and dosage adjustments may be necessary.

Patients should provide a full list of their current medications to their healthcare provider to avoid potential interactions.

Benefits of SAVELINER 400

Effective Phosphate Control

SAVELINER 400 effectively lowers serum phosphate levels, reducing the risk of complications associated with hyperphosphatemia.

Improved Quality of Life

By managing phosphate levels and preventing complications, SAVELINER 400 can significantly improve the quality of life for CKD patients. It helps maintain bone health, reduces cardiovascular risks, and supports overall well-being.

Non-Absorbed Binder

Sevelamer is a non-absorbed binder, meaning it works within the digestive tract without being absorbed into the bloodstream. This reduces the risk of systemic side effects, making it a safer option for long-term use.

Conclusion

SAVELINER 400, containing Sevelamer 400mg, is a vital medication for managing hyperphosphatemia in CKD patients on dialysis. Its ability to bind dietary phosphate and reduce serum phosphate levels helps prevent serious complications, including cardiovascular issues and bone disorders. With its targeted action and generally well-tolerated profile, SAVELINER 400 plays a crucial role in improving the health and quality of life of CKD patients. Patients are encouraged to follow their healthcare provider's instructions regarding dosage and administration, report any side effects, and discuss any potential drug interactions. Through proper use of SAVELINER 400, CKD patients can achieve better phosphate control and enjoy a healthier life. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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