SAVELINER 800 & Sevelamer (800mg).:Tablet- View Uses, Side Effects, Dosage and other....

SAVELINER 800 

Sevelamer (800mg)

SAVELINER 800, is a crucial medication in managing hyperphosphatemia, particularly in patients with chronic kidney disease (CKD) on dialysis. Hyperphosphatemia, a condition characterized by elevated phosphate levels in the blood, can lead to severe complications, including cardiovascular disease and bone disorders. SAVELINER 800 plays a vital role in controlling phosphate levels, thereby enhancing the quality of life for CKD patients.

What is Sevelamer?

Sevelamer is a non-absorbable phosphate binder that works by binding phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. It is available in various formulations, with the 800mg dosage being commonly prescribed. Unlike other phosphate binders, Sevelamer does not contain calcium, which is beneficial in avoiding additional calcium load and the risk of vascular calcification.

Indications for SAVELINER 800

SAVELINER 800 is primarily indicated for:

• Managing Hyperphosphatemia: In CKD patients undergoing hemodialysis or peritoneal dialysis.
• Reducing Serum Phosphate Levels: To maintain optimal phosphate balance and prevent related complications.
• Preventing Secondary Hyperparathyroidism: By controlling phosphate levels, it helps in preventing the overactivity of the parathyroid glands.

How Does SAVELINER 800 Work?

Sevelamer, the active ingredient in SAVELINER 800, works through a unique mechanism:

• Phosphate Binding: Once ingested, Sevelamer binds to dietary phosphate in the gastrointestinal tract.
• Formation of Insoluble Complexes: It forms insoluble complexes with phosphate, which are then excreted in the feces.
• Reduced Phosphate Absorption: This process significantly reduces the absorption of phosphate into the bloodstream, thereby lowering serum phosphate levels.

Dosage and Administration

The dosage of SAVELINER 800 should be individualized based on the patient's serum phosphate levels and response to treatment. Generally, the following guidelines are followed:

• Initial Dose: The typical starting dose is 800 to 1600mg, taken three times a day with meals.
• Adjustment: Dosage adjustments are made based on serum phosphate measurements, aiming to maintain phosphate levels within the target range.
• Maximum Dose: The maximum daily dose should not exceed 14 grams.

Administration Tips

• Take with Meals: To ensure optimal phosphate binding, SAVELINER 800 should be taken with meals.
• Swallow Whole: Tablets should be swallowed whole and not crushed, chewed, or broken.
• Consistent Timing: It is essential to take the medication consistently at the same times each day to maintain stable phosphate levels.

Benefits of SAVELINER 800

SAVELINER 800 offers several benefits, making it a preferred choice for managing hyperphosphatemia in CKD patients:

• Effective Phosphate Control: It effectively lowers serum phosphate levels, reducing the risk of complications.
• Non-Calcium Based: Unlike calcium-based phosphate binders, it does not contribute to hypercalcemia or vascular calcification.
• Improved Quality of Life: By managing phosphate levels, it helps improve the overall quality of life for CKD patients.

Potential Side Effects

While SAVELINER 800 is generally well-tolerated, some patients may experience side effects. Common side effects include:

• Hypophosphatemia: Overuse can lead to abnormally low phosphate levels, causing muscle weakness, bone pain, and other symptoms.

Managing Side Effects

• Dietary Adjustments: Incorporating a balanced diet and, if necessary, vitamin supplements can help manage deficiencies.
• Regular Monitoring: Regular monitoring of serum phosphate and calcium levels can help prevent hypophosphatemia and other complications.

Precautions and Warnings

Before starting SAVELINER 800, it is essential to consider certain precautions:

• Allergies: Patients with known hypersensitivity to Sevelamer or any of its components should avoid using SAVELINER 800.
• Bowel Obstruction: Patients with a history of bowel obstruction or severe gastrointestinal motility disorders should use this medication with caution.
• Pregnancy and Lactation: The safety of Sevelamer in pregnant and lactating women has not been established.

Drug Interactions

SAVELINER 800 may interact with other medications, potentially affecting their absorption and efficacy:

• Fat-Soluble Vitamins: It may reduce the absorption of fat-soluble vitamins (A, D, E, and K).
• Antibiotics: It may interfere with the absorption of certain antibiotics, such as ciprofloxacin. Antibiotics should be taken at least 1 hour before or 3 hours after SAVELINER 800.
• Antiarrhythmics and Anticonvulsants: Close monitoring is necessary when taken with antiarrhythmic or anticonvulsant medications to ensure therapeutic levels are maintained.

Conclusion

SAVELINER 800 (Sevelamer 800mg) is a valuable medication for managing hyperphosphatemia in patients with chronic kidney disease on dialysis. Its unique non-calcium-based formulation and effective phosphate-binding properties make it a preferred choice for healthcare providers. By adhering to the prescribed dosage and administration guidelines, patients can achieve optimal phosphate control, improving their overall health and quality of life. By understanding the benefits, proper usage, and precautions associated with SAVELINER 800, patients and healthcare providers can work together to effectively manage hyperphosphatemia and enhance the overall treatment outcomes for CKD patients on dialysis. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology,Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

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