Spironolactone (100mg) - Dosage, Side Effects, Price, Composition and More…..

Jul 10, 2024

S LACTONE 100 

Spironolactone (100mg)

Introduction

S LACTONE 100, containing 100mg of Spironolactone, is a potent medication used to treat various conditions related to fluid retention, hormonal imbalances, and hypertension. Spironolactone is classified as a potassium-sparing diuretic and an aldosterone antagonist, making it effective for a range of medical conditions. This comprehensive article covers the uses, dosage, side effects, and price, and provides a conclusion on S LACTONE 100, offering detailed information for patients and healthcare providers.

Uses

Spironolactone is commonly used to treat edema (fluid retention) associated with conditions such as:

  • Liver Cirrhosis: Alleviates fluid retention caused by liver dysfunction.
  • Nephrotic Syndrome: Reduces swelling resulting from kidney disease.

Hypertension (High Blood Pressure)

Spironolactone is effective in managing hypertension by:

  • Blocking Aldosterone: Prevents aldosterone from causing sodium and water retention, which can elevate blood pressure.

Hyperaldosteronism

Spironolactone is the treatment of choice for primary hyperaldosteronism, a condition characterized by excessive production of aldosterone, leading to high blood pressure and low potassium levels.

Acne and Hirsutism

Spironolactone is also used off-label to treat hormonal acne and hirsutism (excessive hair growth) in women by:

  • Anti-Androgen Effects: Reducing the effect of androgens (male hormones) that can cause acne and unwanted hair growth.

Heart Failure

Spironolactone can improve survival and reduce hospitalizations in patients with severe heart failure by:

  • Reducing Fluid Overload: Helps manage symptoms related to fluid retention.
  • Improving Heart Function: Alleviates strain on the heart by reducing blood volume.

Mechanism of Action

Spironolactone works by blocking the action of aldosterone, a hormone that regulates the balance of sodium and water in the body. By inhibiting aldosterone, Spironolactone promotes the excretion of sodium and water while retaining potassium, which helps to reduce fluid retention and lower blood pressure.

Dosage

General Dosage Guidelines

  • Edema: 25-200mg per day, depending on the severity of the condition.
  • Hyperaldosteronism: 100-400mg per day, adjusted based on response and tolerance.
  • Acne and Hirsutism: 50-200mg per day, depending on the response and tolerance of the patient.
  • Heart Failure: 12.5-50mg per day, depending on the severity of symptoms and patient tolerance.

Administration Instructions

  1. With or Without Food: Spironolactone can be taken with or without food, although taking it with food may reduce stomach upset.
  2. Consistency: Take the medication at the same times each day to maintain consistent drug levels in the body.
  3. Follow Prescriptions: Always follow the dosage instructions provided by your healthcare provider to ensure optimal effectiveness and reduce the risk of side effects.

Side Effects

Common Side Effects

  • Electrolyte Imbalance: Hyperkalemia (high potassium levels) is a potential side effect due to its potassium-sparing properties.
  • Gastrointestinal Issues: Nausea, vomiting, diarrhea, or stomach cramps may occur.
  • Dizziness: Especially when starting the medication or adjusting the dose.
  • Breast Tenderness or Enlargement: Both in men and women, due to its hormonal effects.

Serious Side Effects

  • Severe Hyperkalemia: Symptoms include muscle weakness, fatigue, and irregular heartbeat. Requires immediate medical attention.
  • Kidney Problems: Indicated by changes in the amount of urine, swelling, and fatigue.

Precautions

  • Medical History: Inform your healthcare provider of any history of kidney disease, liver disease, electrolyte imbalances, or hormonal disorders.
  • Regular Monitoring: Regular blood tests may be required to monitor potassium levels and kidney function.

Price

The cost of S LACTONE 100 can vary based on factors such as brand, location, and pharmacy. On average, a pack of 30 tablets may range from $20 to $60. It is advisable to compare prices across local pharmacies and online retailers. Some insurance plans may cover the cost, reducing out-of-pocket expenses for patients.

Conclusion

S LACTONE 100, with its active ingredient Spironolactone, is an effective treatment for managing conditions like edema, hypertension, hyperaldosteronism, acne, hirsutism, and heart failure. By blocking aldosterone, it helps reduce fluid retention, lower blood pressure, and manage hormonal imbalances. Understanding the proper dosage, potential side effects and cost can help users maximize the benefits of this medication. Always consult a healthcare provider before starting any new treatment to ensure it is suitable for your specific condition and health profile. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology

For further information

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488

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