Sultamicillin Tablets 375 mg – Uses, Dosage, Side Effects & Price

Aug 13, 2025

Introduction

SULTAMYLIN 375 contains Sultamicillin 375 mg, a unique antibiotic formulation that combines ampicillin and sulbactam in a double-ester form. This enhances oral absorption and delivers effective antibacterial action against a wide range of infections caused by susceptible bacteria. It is widely used for respiratory tract infections, urinary tract infections, skin infections, and other bacterial diseases.Sultamicillin is a prodrug – once ingested, it breaks down into ampicillin (the main antibiotic) and sulbactam (a beta-lactamase inhibitor) to combat bacteria and prevent antibiotic resistance.

What is Sultamicillin 375 mg?

Sultamicillin 375 mg is a broad-spectrum oral antibiotic that works by:

  • Ampicillin killing bacteria by disrupting their cell wall synthesis.

  • Sulbactam protecting ampicillin from being destroyed by beta-lactamase enzymes, making the antibiotic more effective.

This combination makes Sultamicillin an excellent choice for treating bacterial infections that might otherwise resist regular penicillin-based antibiotics.

Uses of Sultamicillin Tablets 375 mg

SULTAMYLIN 375 is prescribed for the treatment of:

  • Upper and lower respiratory tract infections (sinusitis, bronchitis, pneumonia)

  • Urinary tract infections (UTIs)

  • Skin and soft tissue infections

  • Tonsillitis and pharyngitis

  • Ear infections (otitis media)

  • Gynecological infections

  • Certain gastrointestinal infections caused by susceptible bacteria

Dosage & Administration

  • The usual adult dose is 375 mg to 750 mg twice daily, depending on the severity and type of infection.

  • Always take with water, preferably after meals to reduce stomach upset.

  • Complete the prescribed course even if symptoms improve to prevent bacterial resistance.

Note: Dosage should be adjusted for patients with kidney impairment and as per doctor’s prescription.

Side Effects of Sultamicillin Tablets 375 mg

Common side effects:

  • Nausea, vomiting, diarrhea

  • Stomach discomfort

  • Mild skin rash

Rare but serious side effects:

  • Allergic reactions (swelling, itching, difficulty breathing)

  • Severe diarrhea (possible Clostridium difficile infection)

  • Liver enzyme changes

Seek medical attention immediately if severe allergic reactions occur.

Precautions Before Using Sultamicillin 375 mg

  • Avoid if allergic to penicillins or cephalosporins.

  • Use with caution in patients with kidney or liver problems.

  • Inform your doctor if you are pregnant or breastfeeding.

  • Avoid unnecessary antibiotic use to prevent resistance.

Drug Interactions

Sultamicillin may interact with:

  • Allopurinol (increased risk of rash)

  • Anticoagulants like warfarin (may increase bleeding risk)

  • Oral contraceptives (may reduce effectiveness – use backup contraception)

  • Methotrexate (may increase toxicity)

Sultamicillin Tablets 375 mg Price

The price of SULTAMYLIN 375 may vary depending on region, distributor, and pack size. Buying from reputed pharmaceutical companies like Steris Healthcare Pvt Ltd ensures competitive pricing and genuine product quality.

Why Buy SULTAMYLIN 375 from Steris Healthcare Pvt Ltd?

  • WHO-GMP & ISO Certified manufacturing for global quality compliance.

  • High-purity ingredients ensuring efficacy and safety.

  • Affordable pricing – often 30% lower than market MRP.

  • Strong pan-India distribution network for timely availability.

  • Transparent, ethical, and patient-focused operations.

  • Convenient ordering and delivery options.

Steris Healthcare is known for its commitment to quality, affordability, and accessibility, making it a trusted choice for both healthcare professionals and patients.

FAQs – Sultamicillin 375 mg

Q1: Can I stop taking SULTAMYLIN 375 when I feel better?
No. Always complete the prescribed course to prevent bacterial resistance and recurrence.

Q2: Can Sultamicillin be taken on an empty stomach?
It can be taken with or without food, but taking after meals may reduce stomach upset.

Q3: Is Sultamicillin effective for viral infections like cold or flu?
No. It only works against bacterial infections.

Q4: Can I drink alcohol while on SULTAMYLIN 375?
Moderate alcohol may not directly interact, but it’s best to avoid alcohol during infection recovery.

Q5: How quickly does Sultamicillin start working?
You may start feeling better within 48–72 hours, but complete the full course as advised.

Conclusion

SULTAMYLIN 375 containing Sultamicillin 375 mg is a powerful and well-tolerated antibiotic for a variety of bacterial infections. By combining ampicillin and sulbactam, it ensures strong antibacterial coverage, even against resistant strains. When purchased from Steris Healthcare Pvt Ltd, patients are assured of quality, affordability, and reliable supply, making it an excellent choice for effective infection management.

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