Temozolomide (250 mg): A Beacon of Hope in Cancer Treatment withTMOZOLMIDE 250 

May 22, 2024

Introduction

TMOZOLMIDE 250 contains Temozolomide 250mg, a potent oral chemotherapy medication used in the treatment of malignant brain tumors, such as glioblastoma multiforme (GBM) and anaplastic astrocytoma. This formulation is part of a class of anti-cancer drugs known as alkylating agents, specifically designed to attack and destroy cancerous cells by disrupting their DNA structure.Temozolomide stands out because of its ability to cross the blood-brain barrier, making it uniquely effective against cancers of the central nervous system (CNS).

Key Features and Composition

  • Brand Name: TMOZOLMIDE 250

  • Active Ingredient: Temozolomide (250mg)

  • Drug Class: Alkylating Agent – Antineoplastic

  • Dosage Form: Oral Capsule

  • Packaging: Blister pack with tamper-proof seal

  • Manufacturing: Produced in WHO-GMP certified facilities

Usage and Indications

TMOZOLMIDE 250 is primarily used in the management of:

  • Glioblastoma Multiforme (GBM) – both newly diagnosed and recurrent cases

  • Anaplastic Astrocytoma – a type of high-grade glioma

  • Off-label uses under oncologist discretion (e.g., metastatic melanoma or other CNS tumors)

Administration Guidelines:

  • Usually taken once daily, often as part of treatment cycles (e.g., 5 days on, 23 days off)

  • Should be taken on an empty stomach, with a full glass of water

  • Capsules must not be opened or chewed

Benefits of TMOZOLMIDE 250

  • Oral chemotherapy – Convenient and effective from home

  • Crosses the blood-brain barrier for CNS targeting

  • Enhances survival when combined with radiation therapy

  • High dosage format (250mg) enables dose customization for advanced protocols

  •    Trusted by oncologists worldwide for brain cancer treatment

How It Works

Temozolomide acts by methylating the DNA of rapidly dividing cancer cells. This process causes errors in DNA replication, leading to cancer cell death. Its chemical structure allows it to effectively penetrate the brain's protective barriers, making it highly suitable for treating tumors within the brain tissue.

Precautions and Side Effects

 Important Precautions:

  • Routine blood count monitoring is required during therapy

  • Avoid during pregnancy and lactation

  • Use effective contraception during and after treatment

  • Should only be used under strict medical supervision

Common Side Effects:

  • Nausea, vomiting

  • Constipation or diarrhea

  • Loss of appetite

  • Fatigue, weakness

  • Low white blood cell count (increased infection risk)

  • Skin rashes or mouth sores

Seek immediate medical attention if symptoms of infection, bleeding, or severe fatigue occur.

Storage Instructions

  • Store below 25°C

  • Protect from light and moisture

  • Keep capsules in original packaging

  • Keep out of reach of children

Frequently Asked Questions (FAQs)

1. What is TMOZOLMIDE 250 used for?
It is used to treat glioblastoma multiforme and anaplastic astrocytoma, aggressive forms of brain cancer.

2. Can I take Temozolomide at home?
Yes, it is an oral chemotherapy medication often taken at home under doctor’s supervision.

3. How should TMOZOLMIDE 250 be taken?
It should be taken on an empty stomach, usually once a day in treatment cycles, as advised by your oncologist.

4. What precautions should I take?
Regular blood tests are necessary. Avoid pregnancy during treatment and for at least 6 months afterward.

5. Are there any interactions with other medicines?
Yes. Inform your doctor about any other medications, especially anti-seizure drugs, steroids, or anticoagulants.

Conclusion

TMOZOLMIDE 250 (Temozolomide 250mg) offers a high-strength, effective oral option for treating advanced brain tumors. Its ability to penetrate the central nervous system, along with ease of use at home, makes it a powerful tool in the modern oncology treatment protocol. Always consult with a qualified oncologist to ensure the safest and most effective use of this medication.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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