Temozolomide (250 mg)-Uses, Side Effects, Dosage & More.......

May 04, 2024

Introduction

TMOZOLMIDE 250 contains Temozolomide 250 mg, an oral chemotherapy medication used in the treatment of brain cancers such as glioblastoma multiforme and anaplastic astrocytoma. This prescription medicine belongs to a class of drugs known as alkylating agents, which work by damaging the DNA of cancer cells, thereby slowing or stopping their growth.Used alone or in combination with radiotherapy, TMOZOLMIDE 250 is a powerful option in managing aggressive brain tumors. It offers a convenient oral alternative to intravenous chemotherapy, making treatment more manageable for patients.

Composition

  • Active Ingredient: Temozolomide – 250 mg

  • Form: Oral Tablet

  • Packaging: Blister Pack or Bottle (as per brand specifications)

  • Route of Administration: Oral

TMOZOLMIDE 250 Tablet Uses

  •  Treatment of Glioblastoma Multiforme (GBM) – an aggressive type of brain cancer

  •  Management of Anaplastic Astrocytoma – a rare malignant brain tumor

  •  May be used in combination with radiation therapy

  •  Used as part of maintenance therapy to prevent recurrence

Key Benefits

  • Oral Chemotherapy – no hospital admission required

  •  Proven efficacy in brain cancer treatment

  •  Can cross the blood-brain barrier, targeting tumor cells effectively

  •  Often used in standard first-line therapy for gliomas

  •  Convenient dosage schedule as prescribed by oncologists

Dosage of TMOZOLMIDE 250

Typical guidelines:

  • Initial phase: Once daily for 5 days in a 28-day cycle

  • Maintenance phase: Doses may increase gradually depending on tolerance and blood test results

  • Take the tablet on an empty stomach, preferably before meals, with water

  • Do not crush or chew the tablet

Always follow your oncologist's instructions carefully.

Side Effects of TMOZOLMIDE 250

Like all chemotherapy drugs, Temozolomide 250 mg can cause side effects. These may include:

Common Side Effects:

  • Nausea and vomiting

  • Loss of appetite

  • Fatigue or tiredness

  • Headache

  • Constipation

Serious Side Effects (report immediately):

  • Low white blood cell count (increased risk of infection)

  • Anemia or thrombocytopenia

  • Severe allergic reactions

  • Liver function changes

  • Shortness of breath or chest pain

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