Teneligliptin + Metformin

Nov 09, 2022

Introduction

TENELIGOLD M 500 is a combination medication containing Metformin SR (500mg) and Teneligliptin (20mg). It is prescribed for the effective management of Type 2 Diabetes Mellitus (T2DM). This formulation works by improving insulin sensitivity, reducing glucose production, and enhancing insulin secretion, ensuring better blood sugar control.

Diabetes is a chronic metabolic disorder that affects millions worldwide. TENELIGOLD M 500 offers a dual approach to controlling blood glucose levels, helping patients maintain a healthier lifestyle and prevent diabetes-related complications.

Key Ingredients

1. Metformin SR (500mg)

  • Belongs to the Biguanide class of antidiabetic medications.

  • Works by reducing hepatic glucose production and increasing insulin sensitivity.

  • Slows down the absorption of glucose from the intestines.

  • Helps in weight management and reduces the risk of cardiovascular complications.

  • Sustained Release (SR) formulation ensures prolonged action, requiring fewer doses.

2. Teneligliptin (20mg)

  • A Dipeptidyl Peptidase-4 (DPP-4) inhibitor that enhances insulin secretion.

  • Prevents the breakdown of incretin hormones, which regulate insulin production.

  • Reduces post-meal blood sugar spikes by increasing the levels of active GLP-1 and GIP hormones.

  • Helps maintain stable HbA1c levels, reducing long-term diabetes-related risks.

Uses of TENELIGOLD M 500

  • Management of Type 2 Diabetes Mellitus.

  • Improvement of insulin sensitivity and pancreatic function.

  • Reduction in fasting and postprandial blood sugar levels.

  • Prevention of diabetic complications such as neuropathy, nephropathy, and retinopathy.

  • Support for weight control and cardiovascular health.

Key Benefits

1. Dual Mechanism for Enhanced Blood Sugar Control

The combination of Metformin SR and Teneligliptin provides comprehensive glucose regulation, reducing both fasting and post-meal sugar spikes.

2. Sustained Release Formulation

Metformin SR allows for longer absorption, reducing the need for frequent dosing and minimizing gastrointestinal side effects.

3. Cardiovascular Protection

Studies suggest that Metformin offers cardioprotective benefits by improving lipid profiles and reducing inflammation, lowering the risk of heart disease.

4. Weight-Neutral and Well-Tolerated

Unlike other antidiabetic drugs that cause weight gain, TENELIGOLD M 500 is weight-neutral, making it suitable for patients with obesity-related diabetes.

5. Lower Risk of Hypoglycemia

Unlike sulfonylureas, Teneligliptin does not cause sudden drops in blood sugar, ensuring steady glucose levels without frequent hypoglycemic episodes.

How Does TENELIGOLD M 500 Work?

  • Metformin SR reduces the liver’s production of glucose, slows down glucose absorption, and increases insulin sensitivity in muscle tissues.

  • Teneligliptin increases incretin hormone levels, boosting insulin secretion in response to high blood sugar while inhibiting excessive glucose production from the liver.

  • Together, these two components help in the effective management of Type 2 Diabetes, offering better glycemic control with fewer side effects.

Directions for Use

  • Dosage: The recommended dose is usually one tablet per day, or as directed by a doctor.

  • Timing: Preferably taken with meals to reduce gastrointestinal discomfort.

  • Consistency: Regular intake is essential for maintaining stable blood sugar levels.

  • Hydration: Drink plenty of water while taking this medication.

  • Lifestyle Modifications: Combine with a healthy diet and regular exercise for best results.

Side Effects of TENELIGOLD M 500

Although generally well-tolerated, some patients may experience mild to moderate side effects, such as:

  • Gastrointestinal discomfort (nausea, diarrhea, bloating)

  • Headache or dizziness

  • Hypoglycemia (rare but possible when combined with other antidiabetic drugs)

  • Lactic Acidosis (rare but serious condition in high-risk patients)

  • Skin rashes or allergic reactions (very rare)

Precautions and Warnings

  • Not recommended for patients with severe kidney or liver disease.

  • Should not be used in patients with Type 1 Diabetes or diabetic ketoacidosis.

  • Pregnant and breastfeeding women should consult a doctor before use.

  • Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis.

Drug Interactions

  • May interact with beta-blockers, corticosteroids, and diuretics, affecting blood sugar control.

  • Should not be taken with other DPP-4 inhibitors or medications that increase lactic acid levels.

  • Regular monitoring of blood glucose levels is recommended when taken with insulin or sulfonylureas.

TENELIGOLD M 500 Price in India

The price of TENELIGOLD M 500 varies depending on the brand, pharmacy, and location. On average, a strip of 10 tablets costs between ₹150 to ₹400. It is available at leading pharmacies and online stores. Discounts and offers may apply when purchasing in bulk.

Storage Instructions

  • Store at room temperature (below 30°C) in a dry place.

  • Keep away from direct sunlight and moisture.

  • Keep out of reach of children and pets.

Conclusion

TENELIGOLD M 500 is a highly effective oral antidiabetic medication that combines the benefits of Metformin SR (500mg) and Teneligliptin (20mg). It helps in achieving better glycemic control, reducing diabetes complications, and improving quality of life. With its dual-action mechanism, weight-neutral profile, and low risk of hypoglycemia, it is a preferred choice for patients with Type 2 Diabetes Mellitus.

For best results, consult a doctor before use and maintain a healthy lifestyle along with the medication.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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