TENELIGOLD M 500 : A Dual-Action Solution for Better Diabetes Control with Metformin SR and Teneligliptin

Introduction

TENELIGOLD M 500 is a combination medication primarily used in the management of type 2 diabetes mellitus. It is a fixed-dose combination of Metformin SR (500mg) and Teneligliptin (20mg). Type 2 diabetes is a chronic condition that affects the way the body processes blood sugar (glucose). Managing blood sugar levels is crucial to prevent complications like heart disease, nerve damage, kidney problems, and eye issues. This medication is designed to help control blood sugar in patients who may not achieve adequate control with monotherapy.

The combination of Metformin SR and Teneligliptin works synergistically to improve glycemic control. It offers patients a more convenient and effective approach to managing their diabetes. Below, we explore the components of TENELIGOLD M 500, its benefits, mechanism of action, side effects, dosage, and much more.

Key Ingredients in TENELIGOLD M 500

1. Metformin SR (500mg): Metformin is one of the most widely prescribed medications for type 2 diabetes. It belongs to the class of drugs known as biguanides. Metformin SR (500mg) refers to the sustained-release form, which ensures a slow and steady release of the drug over time. This helps maintain stable blood sugar levels throughout the day while minimizing gastrointestinal side effects like nausea or upset stomach.

   Metformin works by:

   • Decreasing glucose production in the liver.
   • Enhancing insulin sensitivity, thus helping the body utilize insulin more effectively.
   • Reducing the absorption of glucose from the intestines.

2. Teneligliptin (20mg): Teneligliptin is a DPP-4 (dipeptidyl peptidase-4) inhibitor, which works by blocking the DPP-4 enzyme that breaks down incretin hormones like GLP-1. These hormones help regulate blood sugar levels by stimulating insulin release from the pancreas in response to meals. By inhibiting DPP-4, Teneligliptin helps maintain higher levels of active incretins, promoting better insulin secretion, reducing glucagon secretion, and consequently lowering blood sugar levels.

Benefits of TENELIGOLD M 500

• Improved Glycemic Control: The combination of Metformin SR (500mg) and Teneligliptin (20mg) works together to improve insulin sensitivity, reduce glucose production, and enhance the body's ability to handle glucose after meals.

• Convenient Dosage: With the combination therapy in a single pill, patients benefit from taking just one tablet rather than multiple medications, which increases adherence to treatment.

• Minimal Weight Gain: Unlike some other diabetes medications, Metformin and Teneligliptin typically do not cause significant weight gain, making them preferable choices for patients who need to manage both blood sugar and weight.

• Reduced Risk of Hypoglycemia: Teneligliptin and Metformin do not usually cause low blood sugar (hypoglycemia) when used alone, and thus they offer a safer option for patients who are at risk of hypoglycemia.

How Does TENELIGOLD M 500 Work?

TENELIGOLD M 500 works by combining the effects of Metformin SR (500mg) and Teneligliptin (20mg) to manage blood sugar levels through different mechanisms.

1. Metformin SR (500mg) helps in:

   • Decreasing hepatic glucose production: Metformin inhibits the liver's production of glucose, which is a key contributor to elevated blood sugar levels.
   • Improving insulin sensitivity: By enhancing the body's response to insulin, Metformin helps cells absorb glucose more efficiently.
   • Reducing intestinal glucose absorption: This leads to lower postprandial blood sugar spikes after meals.

2. Teneligliptin (20mg) enhances blood sugar control by:

   • Inhibiting DPP-4 enzyme activity: This increases the levels of GLP-1 and GIP, which stimulate insulin secretion and inhibit glucagon release.
   • Promoting insulin release: In response to food intake, Teneligliptin boosts insulin release, helping to lower blood sugar levels.

Together, these medications offer comprehensive action, targeting multiple aspects of glucose metabolism to achieve better control over blood sugar levels.

Dosage and Administration of TENELIGOLD M 500

The dosage of TENELIGOLD M 500 may vary based on the individual’s condition, blood sugar levels, and response to treatment. The typical starting dose is one tablet (containing 500mg Metformin SR and 20mg Teneligliptin) once a day, preferably with a meal. Depending on the patient’s glycemic control, the dose may be adjusted.

It’s important to follow the doctor’s instructions regarding dosage. The medication should be taken consistently at the same time each day to maximize its effectiveness.

Side Effects of TENELIGOLD M 500

Like any medication, TENELIGOLD M 500 may cause side effects, although not everyone experiences them. Common side effects associated with Metformin SR (500mg) and Teneligliptin (20mg) include:

• Gastrointestinal issues: These may include nausea, vomiting, bloating, or diarrhea. However, sustained-release Metformin is often better tolerated than immediate-release versions.

• Low blood sugar (hypoglycemia): While TENELIGOLD M 500 does not typically cause hypoglycemia on its own, it can occur if used in combination with other diabetes medications like sulfonylureas or insulin.

• Lactic acidosis (rare but serious): A rare side effect of Metformin is lactic acidosis, a serious condition that requires immediate medical attention. Symptoms include weakness, fatigue, and unusual muscle pain.

• Headache or dizziness: These side effects are generally mild and temporary.

• Upper respiratory tract infections: Some patients may experience symptoms like a sore throat or a cough.

Patients should inform their healthcare provider if they experience any unusual or severe side effects. Regular monitoring of kidney function and blood sugar levels is necessary during treatment with TENELIGOLD M 500.

Price of TENELIGOLD M 500

The price of TENELIGOLD M 500 may vary depending on factors such as the country, the pharmacy, and whether the patient has health insurance coverage. In India, TENELIGOLD M 500 is generally affordable and is widely available at most pharmacies. To get the most accurate price, it is recommended to check with local pharmacies.

Precautions and Warnings

Before starting treatment with TENELIGOLD M 500, patients should inform their doctor about their medical history, particularly:

• Kidney disease: Since Metformin is cleared from the body through the kidneys, patients with renal impairment may need a dose adjustment or an alternative medication.

• Liver disease: Both Metformin and Teneligliptin should be used with caution in patients with liver disease.

• Heart conditions: While Teneligliptin and Metformin do not significantly affect heart health, patients with a history of heart disease should be monitored closely.

• Alcohol consumption: Excessive alcohol consumption can increase the risk of lactic acidosis and should be avoided during treatment.

• Pregnancy and breastfeeding: TENELIGOLD M 500 is not recommended for use during pregnancy or breastfeeding unless advised by a doctor.

Monitoring and Follow-up

During treatment with TENELIGOLD M 500, regular follow-up visits to the healthcare provider are necessary. Blood sugar levels should be monitored, and kidney function (creatinine levels) should be assessed periodically, as Metformin is excreted by the kidneys.

Conclusion

TENELIGOLD M 500, a combination of Metformin SR (500mg) and Teneligliptin (20mg), is a highly effective medication for managing type 2 diabetes. It offers multiple mechanisms of action to control blood sugar levels, reduce the risk of complications, and improve the quality of life for patients. By addressing both insulin resistance and glucose production, it provides comprehensive glycemic control. Patients taking TENELIGOLD M 500 should adhere to their prescribed dosages, monitor their blood sugar, and follow up regularly with their healthcare provider to ensure optimal results. This medication, when used as part of a comprehensive diabetes management plan, can significantly improve the management of type 2 diabetes. For anyone considering TENELIGOLD M 500, consulting with a healthcare provider to discuss its potential benefits and risks is essential to ensure it’s the right choice for your diabetes management plan. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, Sterisonline  ,  Sterisindia and Sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

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