Thalidomile 100 & Thalidomide (100mg).Steris Healthcare PVT LTD………

Thalidomile 100

Thalidomide (100mg)

Thalidomile 100 is a potent medication containing Thalidomide(100mg), a drug with a multifaceted history and a broad range of therapeutic applications. Initially introduced in the 1950s as a sedative, Thalidomide gained infamy for causing severe birth defects when used during pregnancy. However, it has been repurposed and rigorously controlled to treat various serious conditions, particularly in oncology and immunology. Thalidomide’s anti-inflammatory, immunomodulatory, and anti-angiogenic properties make it a valuable medication in modern medical practice.

Composition

• Active Ingredient: Thalidomide (100mg)
• Excipients: Lactose monohydrate, magnesium stearate, microcrystalline cellulose, and other inactive ingredients ensuring the stability and effectiveness of the capsule.

Mechanism of Action

Thalidomide exerts its effects through several mechanisms:

• Immunomodulation: Alters the activity and production of cytokines, reducing inflammation and modulating the immune response.
• Anti-Angiogenesis: Inhibits the formation of new blood vessels, which is crucial in preventing the growth and spread of cancer cells.
• Anti-Inflammatory: Reduces inflammation by decreasing the production of tumor necrosis factor-alpha (TNF-α) and other inflammatory mediators.

Indications

Thalidomide 100 is indicated for:

• Multiple Myeloma: Used in combination with other medications to treat newly diagnosed multiple myeloma, particularly in patients who are not candidates for high-dose chemotherapy.
• Erythema Nodosum Leprosum (ENL): Effective in managing the painful skin lesions and other symptoms associated with leprosy.
• Off-Label Uses: Occasionally prescribed for conditions such as Crohn’s disease, HIV-related aphthous ulcers, and graft-versus-host disease under strict medical supervision.

Dosage and Administration

• Multiple Myeloma: The typical starting dose is 200mg per day, but it can be adjusted based on patient response and tolerability. Thalidomide is usually taken at bedtime due to its sedative effects.
• ENL: The recommended dose ranges from 100mg to 300mg per day, depending on the severity of the condition and the patient’s response to treatment.
• Administration: Thalidomide should be taken with a full glass of water, preferably at the same time each day to maintain consistent blood levels.

Benefits

• Effective in Cancer Treatment: Proven efficacy in managing multiple myeloma, leading to improved survival rates and quality of life.
• Reduces Inflammation: Provides significant relief from inflammatory conditions such as ENL.
• Versatile Applications: Used in a variety of off-label conditions where other treatments may not be effective.
• Improved Patient Outcomes: Enhances the effectiveness of combination therapies, particularly in oncology.

Side Effects

While Thalidomide 100 is highly effective, it may cause some side effects, including:

• Peripheral Neuropathy: Numbness, tingling, or pain in the hands and feet, which can become permanent if not addressed promptly.
• Sedation: Drowsiness and dizziness are common, especially when taken at bedtime.
• Constipation: A frequent side effect that can often be managed with dietary adjustments and laxatives.
• Thromboembolic Events: Increased risk of blood clots, especially when used in combination with other medications for multiple myeloma.
• Skin Reactions: Rash, dry skin, and itching may occur in some patients.

Precautions and Warnings

• Pregnancy Risk: Thalidomide is highly teratogenic and can cause severe birth defects. Women of childbearing potential must use two forms of contraception and undergo regular pregnancy testing.
• Regular Monitoring: Patients should be regularly monitored for signs of peripheral neuropathy and blood clotting.
• Contraindications: Not suitable for patients with a history of severe thrombosis or known hypersensitivity to Thalidomide.
• Drug Interactions: Care should be taken when combining Thalidomide with other medications, particularly those that affect the nervous system or blood clotting.

Conclusion

Thalidomile 100, with its active ingredient Thalidomide, has transformed from a controversial drug to a crucial medication in treating multiple myeloma and other serious inflammatory conditions. Its unique mechanisms of action, including immunomodulation, anti-angiogenesis, and anti-inflammatory effects, make it a powerful tool in modern medicine. Despite potential side effects and the necessity for stringent precautions, Thalidomile 100 remains indispensable in oncology and immunology, offering hope and improved outcomes for many patients. With careful monitoring and adherence to prescribed guidelines, patients can benefit significantly from Thalidomile 100 in managing their conditions effectively.Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

CALL/WHATSAPP: 7877551268, 7849827488

BUY NOW