TMOZOLMIDE 250 : Temozolomide (250mg) .....

TMOZOLMIDE 250

Temozolomide (250mg)

TMOZOLMIDE 250, containing Temozolomide (250mg), is a potent oral chemotherapy medication primarily used to treat aggressive brain tumors, including glioblastoma multiforme (GBM) and anaplastic astrocytoma. As an alkylating agent, Temozolomide works by damaging the DNA of cancer cells, inhibiting their growth and proliferation. This medication has become a cornerstone in neuro-oncology due to its efficacy in crossing the blood-brain barrier, allowing it to target brain tumors effectively.

Uses

TMOZOLMIDE 250 is primarily used for:

• Glioblastoma Multiforme (GBM): Temozolomide is the standard treatment for newly diagnosed GBM, the most aggressive type of primary brain tumor.
• Anaplastic Astrocytoma: It is also used to treat anaplastic astrocytoma, a high-grade malignant brain tumor.
• Other Brain Tumors: Temozolomide may be used off-label for other types of brain tumors under specific circumstances.

Dosage

The dosage of TMOZOLMIDE 250 is tailored to the patient’s medical condition, body surface area (BSA), response to treatment, and other individual factors. It is crucial to follow the doctor’s instructions carefully. Here is a general guideline:

• For Newly Diagnosed Glioblastoma: The initial dose is 75 mg/m² once daily for 42 days, concurrent with radiotherapy. After a 4-week break, the maintenance dose is 150 mg/m² once daily for 5 days per 28-day cycle, which may be increased to 200 mg/m² based on patient tolerance and blood counts.
• For Recurrent Anaplastic Astrocytoma: The recommended dose is 150 mg/m² once daily for 5 days per 28-day cycle, potentially increasing to 200 mg/m² if well tolerated.

Temozolomide should be taken on an empty stomach, either one hour before or two hours after a meal, to ensure optimal absorption and minimize gastrointestinal side effects.

Side Effects

As with any chemotherapy medication, TMOZOLMIDE 250 can cause side effects. Patients should be aware of these potential adverse effects and consult their healthcare provider if they experience any unusual symptoms. Common side effects include:

• Nausea and Vomiting: These are the most common side effects and can often be managed with antiemetic medications.
• Fatigue: Feeling unusually tired or weak is common.
• Constipation: Patients may experience constipation, requiring dietary adjustments or laxatives.
• Headache: Some patients may experience headaches.
• Loss of Appetite: A decrease in appetite is common during treatment.
• Low Blood Counts: Temozolomide can cause a decrease in white blood cells, red blood cells, and platelets, increasing the risk of infection, anemia, and bleeding.
• Hair Loss: Temporary hair loss may occur.
• Rash: Skin rashes can develop in some patients.

Patients should report any severe or persistent side effects to their healthcare provider promptly. Regular blood tests are necessary to monitor blood counts and adjust the dosage as needed to ensure safe and effective treatment.

Price

The price of TMOZOLMIDE 250 can vary based on the brand, location, and pharmacy. In India, the approximate price range for a strip of 5 capsules is between ₹7000 to ₹15000. It is advisable to check with local pharmacies for the most accurate and up-to-date pricing.

Conclusion

TMOZOLMIDE 250 (Temozolomide 250mg) is an essential medication in the treatment of aggressive brain tumors such as glioblastoma multiforme and anaplastic astrocytoma. Its ability to cross the blood-brain barrier makes it particularly effective in targeting brain tumors. Adhering to the prescribed dosage and schedule is crucial for maximizing the effectiveness of the medication and minimizing side effects. Regular monitoring by a healthcare provider is vital to manage any potential adverse effects and make necessary adjustments to the treatment regimen. Patients should maintain open communication with their healthcare team and report any concerning symptoms promptly. With careful management, TMOZOLMIDE 250 can significantly improve patient outcomes and quality of life in those battling these challenging medical conditions.

Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

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