Tolvaptan 30 mg Uses,Mechanism of Action & Side Effects

Patients living with kidney-related disorders or sodium imbalance often struggle with symptoms like fatigue, swelling, and frequent hospital visits. One of the trusted medicines prescribed in such cases is Tolvaptan 30 mg, sold under the brand name TOLVAPTORIS 30. This medicine helps manage hyponatremia, supports kidney health in polycystic kidney disease, and improves overall quality of life.

If you are looking to understand tolvaptan, its uses, dose, side effects, and mechanism of action, this article covers everything in detail.

What is Tolvaptan 30 mg Tablet?

Tolvaptan 30 mg tablet is a selective vasopressin V2 receptor antagonist. It helps the kidneys excrete excess water while preserving sodium balance. This is why tolvaptan is highly effective in treating low sodium levels and slowing kidney damage in autosomal dominant polycystic kidney disease (ADPKD).

Doctors prescribe tolvaptan 30 mg tab as part of a treatment plan that may include lifestyle adjustments and regular monitoring of sodium and liver function.

Tolvaptan 30 mg Uses

The main uses of tolvaptan 30 mg include:

• Hyponatremia (low sodium in blood): Common in patients with SIADH, heart failure, or liver cirrhosis.

• Autosomal Dominant Polycystic Kidney Disease (ADPKD): Slows down cyst growth and kidney damage, delaying the need for dialysis or transplantation.

• Fluid overload conditions: Helps reduce excess fluid buildup in heart and liver disorders.

Tolvaptan Mechanism of Action

The mechanism of action of tolvaptan is unique. Normally, the hormone vasopressin signals the kidneys to retain water. Tolvaptan 30 mg works by blocking vasopressin from binding to V2 receptors in the kidneys. This action increases urine output (aquaresis) while protecting sodium and potassium levels.

This dual effect not only corrects sodium imbalance but also prevents cyst growth in ADPKD patients.

Tolvaptan Dose

The exact tolvaptan dose depends on the patient’s condition and medical supervision.

• For hyponatremia, treatment often begins with a lower dose and is adjusted depending on the sodium response.

• For ADPKD, tolvaptan 30 mg tab may be prescribed in a dose-titration regimen, often alternating with other strengths (15 mg, 60 mg, 90 mg) for effective control.

Patients must drink adequate water during therapy to avoid dehydration. Never change the tolvaptan dose without consulting your doctor.

Tolvaptan Side Effects

Like any medicine, tolvaptan 30 mg can cause side effects. Most are manageable, but some require monitoring.

Common side effects:

• Thirst

• Frequent urination

• Dry mouth

• Headache

• Dizziness

Serious side effects (less common):

• Liver function abnormalities (requires regular testing)

• Dehydration and rapid weight loss

• Signs of liver injury like yellowing of eyes/skin or dark urine

If you notice severe symptoms, consult your doctor immediately.

Why Choose Steris Healthcare for Tolvaptan?

At Steris Healthcare, we ensure that medicines like TOLVAPTORIS 30  are manufactured with the highest standards of safety and quality.

• WHO-GMP certified plants guarantee global-standard manufacturing.

• Pan-India distribution network ensures availability everywhere.

• Affordable pricing so that patients receive effective treatment without financial burden.

• Wide therapeutic portfolio supporting doctors across multiple specialities.

Choosing Steris Healthcare means choosing reliability, care, and patient well-being.

Frequently Asked Questions

Q1: Tolvaptan belongs to which class of drug?
Tolvaptan belongs to the class of vasopressin V2 receptor antagonists.

Q2: How does Tolvaptan work?
It blocks vasopressin hormone at kidney receptors, increasing urine output while maintaining sodium balance and slowing cyst growth in ADPKD.

Q3: Can I take Tolvaptan long-term?
Yes, in conditions like ADPKD, patients may need long-term therapy under strict medical monitoring.

Q4: What precautions should I follow on Tolvaptan?
Stay hydrated, avoid alcohol, and undergo liver function tests regularly.

Q5: Is Tolvaptan safe during pregnancy?
It is generally not recommended in pregnancy or breastfeeding unless specifically prescribed.

Final Thoughts

Tolvaptan 30 mg is a proven treatment option for patients with low sodium levels and kidney disease. Its unique ability to maintain fluid balance and slow disease progression makes it an essential medicine under the guidance of a healthcare professional.

At Steris Healthcare, we are proud to make tolvaptan 30 mg tablets available across India with a focus on quality, affordability, and patient care.