Tranexamic acid and Mefenamic Acid

Introduction

TENXIMA MF is a combination medication containing Tranexamic Acid (500mg) and Mefenamic Acid (250mg). It is primarily used to treat heavy menstrual bleeding (menorrhagia) and pain associated with menstruation. This combination works by reducing excessive blood loss and providing relief from pain and inflammation.

Tranexamic Acid helps prevent the breakdown of blood clots, thus reducing excessive bleeding, while Mefenamic Acid acts as a non-steroidal anti-inflammatory drug (NSAID) to relieve menstrual cramps and pain.

This article provides a comprehensive guide to TENXIMA MF, including its uses, dosage, benefits, side effects, precautions, and more.

Key Ingredients

1. Tranexamic Acid (500mg)

• An antifibrinolytic agent that helps in blood clot formation

• Prevents excessive bleeding by blocking the breakdown of fibrin (clot-forming protein)

• Used in treating heavy menstrual bleeding, nosebleeds, post-surgical bleeding, and hemophilia

2. Mefenamic Acid (250mg)

• A non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation

• Works by inhibiting prostaglandin synthesis, substances responsible for pain and swelling

• Commonly used to relieve menstrual cramps (dysmenorrhea), arthritis pain, and post-surgical pain

Uses of TENXIMA MF

TENXIMA MF is prescribed for various medical conditions, primarily related to menstrual bleeding and pain.

1. Heavy Menstrual Bleeding (Menorrhagia)

• Helps reduce excessive blood loss during periods

• Controls abnormal bleeding patterns

• Prevents iron deficiency anemia caused by prolonged heavy bleeding

2. Dysmenorrhea (Menstrual Pain and Cramps)

• Relieves painful cramps by reducing inflammation

• Provides comfort during periods

3. Post-Surgical Bleeding

• Used to prevent excessive bleeding after surgeries such as dental extractions or gynecological procedures

4. Nosebleeds (Epistaxis)

• Helps control frequent or heavy nosebleeds by promoting blood clotting

5. Other Bleeding Disorders

• Can be prescribed for conditions like hemophilia, where blood does not clot properly

How Does TENXIMA MF Work?

1. Tranexamic Acid

• Works by inhibiting plasmin, an enzyme that dissolves blood clots

• Prevents fibrinolysis (breakdown of clots), thereby reducing excessive bleeding

2. Mefenamic Acid

• Blocks cyclooxygenase (COX) enzymes, reducing prostaglandins

• Lowers pain sensitivity and inflammation

• Provides effective pain relief during menstruation and other painful conditions

Dosage and Administration

The dosage of TENXIMA MF depends on the severity of the condition and the doctor's prescription.

Recommended Dosage:

• For Heavy Menstrual Bleeding: 1 tablet two to three times a day for a maximum of 5 days during menstruation

• For Pain Relief: 1 tablet every 8 hours as needed

Administration Instructions:

• Take the tablet with or after food to prevent gastric irritation

• Swallow the tablet whole with water

• Do not exceed the prescribed dose

Side Effects of TENXIMA MF

Like any medication, TENXIMA MF may cause side effects. While most are mild, some may require medical attention.

Common Side Effects:

• Nausea and vomiting

• Diarrhea or constipation

• Headache

• Stomach pain or cramps

• Heartburn or indigestion

Rare but Serious Side Effects:

• Allergic reactions (rash, swelling, difficulty breathing)

• Blood clot formation (increased risk of thrombosis)

• Kidney or liver dysfunction

• Blurred vision or dizziness

Precautions and Warnings

Before taking TENXIMA MF, consider the following precautions:

Who Should Avoid TENXIMA MF?

• Patients with a history of blood clot disorders (deep vein thrombosis, pulmonary embolism, stroke)

• Those with severe kidney disease

• Individuals with active stomach ulcers or gastrointestinal bleeding

• People with allergy to NSAIDs (e.g., ibuprofen, aspirin)

• Pregnant or breastfeeding women (consult a doctor before use)

Important Warnings:

• Do not take TENXIMA MF with alcohol – It may increase the risk of stomach bleeding

• Avoid long-term use – Prolonged NSAID use can cause kidney or liver problems

• Monitor blood pressure – Tranexamic acid may slightly increase blood pressure

Drug Interactions

TENXIMA MF may interact with other medications, affecting their efficacy.

Avoid Taking TENXIMA MF With:

• Anticoagulants (e.g., Warfarin, Heparin) – May increase the risk of blood clotting

• Other NSAIDs or Aspirin – Increases risk of stomach ulcers and bleeding

• Hormonal Contraceptives (Birth Control Pills) – Can elevate the risk of blood clots

• Antidepressants (SSRIs like Fluoxetine, Sertraline) – May increase the risk of bleeding complications

Price in India

The price of TENXIMA MF varies depending on the brand and pharmacy. Generally, a strip of 10 tablets costs around ₹150 - ₹300 INR in India. However, prices may differ based on availability and discounts.

Frequently Asked Questions (FAQs)

1. Can TENXIMA MF be taken daily?

No, it should be taken only during heavy menstrual bleeding or pain episodes. Do not use it for more than 5 consecutive days unless prescribed by a doctor.

2. Is TENXIMA MF safe for pregnant women?

It is not recommended during pregnancy unless prescribed by a doctor, as it may affect blood clotting and fetal development.

3. Can I take TENXIMA MF with milk?

Yes, taking it with milk or food can help reduce stomach irritation.

4. How long does it take to show results?

TENXIMA MF starts working within 30-60 minutes, with peak effects observed in 2-3 hours.

5. What should I do if I miss a dose?

Take the missed dose as soon as you remember. However, if it’s close to the next dose, skip it and continue with the regular schedule. Do not double dose.

Conclusion

TENXIMA MF, a combination of Tranexamic Acid (500mg) and Mefenamic Acid (250mg), is an effective medication for heavy menstrual bleeding and menstrual pain. It provides quick relief, prevents excessive blood loss, and helps maintain menstrual health.

While it is a safe and effective treatment, it is essential to follow the recommended dosage, precautions, and medical advice to avoid side effects. Always consult a doctor before using TENXIMA MF, especially if you have a history of blood clotting disorders, stomach ulcers, or kidney disease.

If you experience severe side effects or unusual bleeding, seek medical attention immediately. Proper usage of TENXIMA MF can significantly improve menstrual health and overall well-being.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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