TURBOFINE 250 : Terbinafine IP (250mg) Uses, Dosage, Side Effects, Price, and Conclusion.....

Jul 13, 2024

TURBOFINE 250, formulated with Terbinafine 250 mg, is an advanced antifungal medicine widely used for treating a spectrum of fungal infections affecting the skin, nails, and scalp. Terbinafine belongs to the allylamine class of antifungal agents and is known for its strong fungicidal action, meaning it kills fungal cells directly rather than merely stopping their growth.

In recent years, fungal infections have become increasingly common in India due to humid weather, sweating, pollution, poor hygiene, tight clothing, lifestyle factors, and widespread steroid-based cream misuse. Conditions like ringworm (tinea corporis), jock itch (tinea cruris), athlete’s foot (tinea pedis), and fungal nail infections (onychomycosis) are frequently reported in dermatology OPDs. TURBOFINE 250 offers an effective, reliable, and scientifically proven treatment option for such infections.

Once taken orally, Terbinafine rapidly reaches the skin, nails, and hair follicles, maintaining potent antifungal concentrations for an extended period. This makes TURBOFINE 250 one of the most preferred systemic antifungal medicines for moderate to severe fungal infections or those that do not respond to topical creams alone.

Its unique mechanism targets the fungal cell membrane by inhibiting an enzyme called squalene epoxidase, leading to the accumulation of toxic fungal metabolites and eventually killing the fungus. Due to its strong activity and long-lasting results, TURBOFINE 250 has become a trusted choice among dermatologists.

Uses

TURBOFINE 250 is prescribed for various fungal infections caused by dermatophytes, moulds, and yeasts. Its primary uses include:

1. Tinea Corporis (Ringworm of the Body)

Effective for red, itchy, circular patches commonly seen on arms, legs, trunk, and neck.

2. Tinea Cruris (Jock Itch)

Used for fungal infections in the groin area, causing itching, redness, and burning sensations.

3. Tinea Pedis (Athlete’s Foot)

Relieves fungal infection of the feet, cracks between toes, scaling, and foul smell.

4. Tinea Capitis (Fungal Scalp Infection)

Recommended for fungal infections of the scalp, especially in children and young adults.

5. Tinea Barbae (Beard Area Infection)

Useful in men who experience itching, redness, and fungal infection in the beard region.

6. Onychomycosis (Fungal Nail Infection)

One of the most effective medicines for fungal toenail and fingernail infections.
Helps reduce discolouration, thickening, brittleness, and nail deformity.

7. Cutaneous Candidiasis

Treats yeast infections caused by Candida species on the skin.

8. Pityriasis Versicolor

Useful in cases where fungus leads to white or brown discoloured patches on the skin.

9. Recurrent or Resistant Fungal Infections

Ideal when topical creams fail to provide relief, or infections keep returning.

10. Chronic Dermatophyte Infections

Recommended for persistent, long-standing fungal infections requiring deeper penetration.

Benefits

TURBOFINE 250 offers several advantages that make it one of the most prescribed antifungal tablets:

1. Strong Fungicidal Action

Unlike many antifungals that only stop fungal growth, Terbinafine kills fungal cells, ensuring faster and long-lasting results.

2. Deep Penetration into Skin and Nails

Reaches the deeper layers where fungi multiply, improving treatment outcomes, especially in nail infections.

3. Long-lasting Protection

Even after the treatment stops, therapeutic levels remain in the skin and nails for weeks, preventing recurrence.

4. Fast Symptom Relief

Reduces itching, redness, scaling, and burning sensations within the first few days of therapy.

5. Ideal for Widespread and Multiple-site Infections

Helpful in patients with large skin involvement, multiple patches, or recurrent fungal infections.

6. Effective for Nail Fungal Infections

One of the few oral medicines clinically proven to restore healthy nail growth.

7. Convenient Once-daily Dosing

Improves compliance and ensures steady antifungal coverage.

8. High Safety Profile

Well-tolerated by most patients when taken under medical supervision.

9. Works When Topical Creams Fail

Essential for moderate to severe fungal infections where creams alone are insufficient.

Dosage

The dosage of TURBOFINE 250 varies depending on the severity and location of infection. It must be taken exactly as prescribed by a healthcare provider.

1. Standard Adult Dosage

  • One tablet (250 mg) once daily with or without food.

2. Treatment Duration

Skin Infections

  • 2–4 weeks for tinea corporis, cruris, and pedis.

Scalp Infections (Tinea Capitis)

  • 4–6 weeks or as directed.

Nail Infections (Onychomycosis)

  • Fingernails: 6 weeks

  • Toenails: 12 weeks or longer

  • Some patients may require extended therapy based on nail growth rate.

3. Elderly Patients

Dose adjustment may be necessary based on liver and kidney function.

4. Children

Terbinafine oral tablets are usually not recommended unless specifically prescribed by a pediatric dermatologist.

5. Missed Dose

  • Take it as soon as you remember.

  • Skip if it's almost time for the next dose—never double-dose.

6. Overdose

Symptoms may include:

  • Headache

  • Nausea

  • Dizziness

  • Rash
    Seek immediate medical assistance if overdose is suspected.

Side Effects

TURBOFINE 250 is generally safe, but some individuals may experience side effects, depending on their health condition, metabolism, and sensitivity.

Common Side Effects

  • Headache

  • Stomach discomfort

  • Indigestion

  • Diarrhoea

  • Loss of appetite

  • Mild skin rash

  • Taste disturbance (usually temporary)

Less Common Side Effects

  • Joint or muscle pain

  • Tiredness

  • Changes in smell or taste

  • Mild liver enzyme elevation

Rare but Serious Side Effects

Seek immediate medical attention if any of the following occur:

  • Severe rash or blistering

  • Persistent nausea or vomiting

  • Dark urine, pale stools

  • Yellowing of eyes/skin (jaundice)

  • Serious liver problems

  • Loss of taste that persists beyond treatment

  • Allergic reactions (swelling, breathing difficulty)

Precautions and Warning

Before using TURBOFINE 250, patients should be aware of the following precautions:

1. Liver Disease

Not recommended for individuals with active or chronic liver disorders.
Baseline liver function tests may be required.

2. Kidney Problems

Dose adjustments may be required in severe renal impairment.

3. Alcohol Consumption

Avoid alcohol while taking Terbinafine as it increases liver toxicity risk.

4. Pregnancy

Use only if clearly needed and prescribed. Safety data in pregnancy is limited.

5. Breastfeeding

Terbinafine passes into breast milk and is usually avoided.

6. Drug Interactions

Inform your doctor if you use:

  • Antidepressants

  • Beta-blockers

  • Blood thinners

  • Antiarrhythmics

  • Other antifungal medicines

7. Avoid Self-medication

Fungal infections require correct diagnosis; misuse can worsen the condition.

8. Steroid Cream Usage

Avoid simultaneous use of steroid creams unless prescribed.
Steroids worsen fungal infections and delay cure.

9. Follow Full Course

Stopping early may lead to recurrence and resistance.

10. Skin Allergy History

Inform your doctor if you have eczema, psoriasis, or hypersensitivity.

Conclusion

TURBOFINE 250 (Terbinafine 250 mg) is a powerful and dependable antifungal medicine widely used for treating a variety of fungal infections affecting the skin, nails, and scalp. With its strong fungicidal activity, deep penetration, and long-lasting protection, it provides faster relief and higher cure rates compared to many other antifungal treatments.

Frequently Asked Questions (FAQs)

1. What is TURBOFINE 250 used for?

It is used to treat fungal infections like ringworm, jock itch, athlete’s foot, fungal nail infections, and scalp infections.

2. How long does Terbinafine take to work?

Symptoms begin improving within a few days, but complete cure may take several weeks depending on the infection type.

3. Can TURBOFINE 250 treat nail fungus?

Yes. It is one of the most effective oral treatments for fungal nail infections.

4. Should I avoid alcohol while taking this medicine?

Yes, alcohol increases the risk of liver-related side effects.

5. Can I stop taking the tablet once the itching reduces?

No. Complete the full course to prevent recurrence.

6. Is TURBOFINE 250 safe for diabetic patients?

Yes, but monitoring is advised, especially for foot infections.

7. Can pregnant women take Terbinafine?

Use only if recommended by a doctor.

8. Why do fungal infections keep returning?

Causes may include poor hygiene, sweating, tight clothing, steroid cream misuse, or not completing the treatment course.

9. Is this medicine habit forming?

No, it is not habit-forming.

10. What to do if I miss a dose?

Take it when remembered, but do not double the dose.

 

 

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