Vildiabate 100 & Vildagliptin (100mg)].:Tablet- View Uses, Side Effects, Dosage, Mechanism of action...

Vildiabate 100

Vildagliptin (100mg)]

Vildiabate 100 is a high-dose formulation of Vildagliptin(100mg)], a potent dipeptidyl peptidase-4 (DPP-4) inhibitor. It is primarily used for the management of Type 2 diabetes mellitus by improving glycemic control in adults. Vildiabate 100 offers a powerful and effective solution for patients who need more substantial support in maintaining their blood glucose levels within the target range, thereby reducing the risk of diabetes-related complications.

Composition

• Active Ingredient: Vildagliptin (100mg)
• Excipients: Microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, magnesium stearate, and other inactive ingredients that ensure the stability and efficacy of the tablet.

Mechanism of Action

Vildagliptin, the active component of Vildiabate 100, works by inhibiting the enzyme DPP-4, which is responsible for breaking down incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a critical role in regulating blood glucose levels. By inhibiting DPP-4, Vildagliptin increases the levels of active incretin hormones, enhancing insulin secretion and reducing glucagon release, which helps lower blood glucose levels, especially after meals.

Indications

Vildiabate 100 is indicated for:

• Type 2 Diabetes Mellitus: Used as monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin to improve glycemic control in adults with Type 2 diabetes.

Dosage and Administration

• Standard Dosage: The recommended dose of Vildiabate 100 is 100mg once daily. The dosage may be adjusted based on the patient’s needs and the prescribing physician’s advice.
• Administration: Vildiabate 100 can be taken with or without food. It should be swallowed whole with water, preferably at the same time each day to maintain consistent blood levels.
• Dose Adjustments: Adjustments may be necessary based on the patient's renal function and response to treatment. Regular monitoring of blood glucose levels is essential to ensure optimal dosing.

Benefits

• Improved Glycemic Control: Helps to maintain blood glucose levels within the target range, reducing the risk of hyperglycemia.
• Convenient Dosing: Available in a once-daily dosing regimen, enhancing patient compliance.
• Reduced Risk of Hypoglycemia: Compared to some other antidiabetic medications, Vildagliptin has a lower risk of causing hypoglycemia.
• Weight Neutral: Unlike some antidiabetic agents, Vildagliptin does not typically lead to weight gain, making it suitable for overweight or obese patients.

Side Effects

While Vildiabate 100 is generally well-tolerated, it may cause some side effects, including:

• Gastrointestinal Issues: Nausea, vomiting, and diarrhea may occur, especially during the initial phase of treatment.
• Headache: Some patients may experience headaches.
• Dizziness: Mild dizziness can occur but usually diminishes over time.
• Nasopharyngitis: Inflammation of the nasal passages and throat is a common side effect.
• Rare but Serious Side Effects: Pancreatitis and severe allergic reactions, including rash, itching, and swelling, may occur in rare cases. Immediate medical attention is required if these symptoms develop.

Precautions and Warnings

• Renal Function Monitoring: Patients with renal impairment should have their kidney function regularly monitored, and dose adjustments may be necessary.
• Liver Function Tests: Liver enzymes should be checked before starting treatment and periodically thereafter, as Vildagliptin can cause liver enzyme elevations.
• Contraindications: Not recommended for patients with a history of severe hypersensitivity to Vildagliptin or any of its components.
• Pregnancy and Nursing: The safety of Vildagliptin during pregnancy and breastfeeding has not been established. It should only be used if the potential benefits justify the potential risks.

Drug Interactions

• Other Antidiabetic Agents: When used in combination with other antidiabetic medications, there may be an increased risk of hypoglycemia.
• ACE Inhibitors: Concurrent use may increase the risk of angioedema.
• Corticosteroids: These may reduce the blood glucose-lowering effect of Vildagliptin.

Conclusion

Vildiabate 100, containing a higher dose of Vildagliptin, offers a highly effective option for managing Type 2 diabetes mellitus. Its mechanism of action, which involves enhancing incretin hormone levels, helps to regulate blood glucose levels effectively. With benefits such as improved glycemic control, a convenient once-daily dosing regimen, and a lower risk of hypoglycemia, Vildiabate 100 is a valuable addition to diabetes management. Regular monitoring and adherence to prescribed guidelines are crucial for maximizing the therapeutic benefits and minimizing potential side effects. Vildiabate 100 remains a cornerstone in the treatment of Type 2 diabetes, helping patients achieve better health outcomes and improved quality of life.Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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