voglibose 02 mg metformin sr 500
Jul 05, 2022
Introduction:
Vogligold M 0.2 is a pharmaceutical combination commonly used in the management of type 2 diabetes mellitus. It contains two active ingredients—Voglibose (0.2 mg) and Metformin SR (500 mg). This medication is prescribed to help control blood sugar levels in diabetic patients by improving the body’s ability to use insulin effectively and reducing the absorption of glucose from the digestive tract. Type 2 diabetes is a chronic condition that affects how the body processes glucose (sugar), and controlling blood sugar levels is critical in preventing complications like nerve damage, kidney disease, and cardiovascular problems.
In this article, we will explore the components of Vogligold M 0.2, its mechanism of action, dosage guidelines, side effects, and more, providing an in-depth understanding of how this combination medication works in diabetes management.
Key Ingredients:
Vogligold M 0.2 combines two active ingredients that work synergistically to help manage blood glucose levels:
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Voglibose (0.2 mg): Voglibose is an alpha-glucosidase inhibitor that works by inhibiting the enzymes responsible for breaking down carbohydrates in the digestive system. By slowing the absorption of glucose from the intestine into the bloodstream, it helps prevent sharp spikes in blood sugar levels after meals. This makes it particularly useful for postprandial (after-meal) hyperglycemia.
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Metformin SR (500 mg): Metformin is one of the most commonly prescribed medications for type 2 diabetes. It works by reducing the amount of glucose produced by the liver and increasing the sensitivity of muscle cells to insulin. This helps to lower blood sugar levels and improves the body's overall insulin response. The SR (sustained-release) formulation of metformin ensures a slower and more consistent release of the drug into the bloodstream, reducing the chances of gastrointestinal side effects and improving patient compliance.
How Does Vogligold M 0.2 Work?
The combination of Voglibose and Metformin in Vogligold M 0.2 provides a multifaceted approach to controlling blood glucose levels.
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Voglibose’s Role:
- Voglibose slows down the digestion of carbohydrates by inhibiting the alpha-glucosidase enzyme, which is responsible for breaking down complex carbohydrates into simpler sugars.
- This leads to a delayed absorption of glucose from the intestine, preventing the sharp post-meal blood sugar spikes that are commonly seen in people with type 2 diabetes.
- As a result, it helps maintain more stable blood glucose levels after meals.
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Metformin’s Role:
- Metformin works by reducing glucose production in the liver. In type 2 diabetes, the liver often produces excessive glucose, which contributes to high blood sugar levels.
- Additionally, Metformin enhances insulin sensitivity in peripheral tissues (muscles and fat cells), making it easier for insulin to facilitate the uptake of glucose from the bloodstream into cells.
- By improving the body’s use of insulin, Metformin helps reduce overall blood sugar levels and contributes to long-term glycemic control.
Indications:
Vogligold M 0.2 is primarily used to treat type 2 diabetes mellitus in adult patients. It is especially beneficial for those who are unable to control their blood sugar levels through diet and exercise alone. The medication is generally prescribed as part of a comprehensive diabetes management plan, which may include other lifestyle changes and medications.
It may be used when:
- Diet and exercise alone are not sufficient to control blood sugar levels.
- The patient has a history of inadequate response to single-agent therapy with either metformin or voglibose.
- It is important to manage both fasting and postprandial blood sugar levels.
Dosage and Administration:
The usual starting dose of Vogligold M 0.2 is one tablet per day, typically taken with meals to minimize the risk of gastrointestinal discomfort, which is common with both Voglibose and Metformin. The exact dosage may vary depending on the patient's individual needs, health condition, and response to treatment. A healthcare professional will determine the appropriate dose based on these factors.
- Recommended Dosage:
- For adults, the standard dose is usually one tablet (containing 0.2 mg of Voglibose and 500 mg of Metformin SR) taken with a meal, once or twice a day.
- The dosage can be adjusted by the healthcare provider based on blood sugar levels and individual tolerance to the medication.
Precautions and Warnings:
Before starting Vogligold M 0.2, it is essential to inform the healthcare provider about any existing medical conditions, allergies, or other medications being taken, as these may influence the choice of treatment or dosage. Specific precautions include:
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Kidney Disease: Metformin should be used with caution in patients with kidney dysfunction, as it is primarily excreted by the kidneys. Impaired kidney function can lead to an accumulation of the drug in the body, increasing the risk of side effects.
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Liver Disease: Both Voglibose and Metformin may have adverse effects on liver function, so patients with liver disease should use this medication cautiously.
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Hypoglycemia: While Vogligold M 0.2 generally does not cause hypoglycemia (low blood sugar), when used in combination with other blood sugar-lowering agents, there may be an increased risk. Symptoms of hypoglycemia may include shaking, sweating, confusion, and dizziness.
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Alcohol Consumption: Drinking alcohol can increase the risk of lactic acidosis, a rare but serious side effect of Metformin. Patients are advised to limit alcohol intake while using this medication.
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Pregnancy and Breastfeeding: Vogligold M 0.2 should be used with caution during pregnancy, and only if the potential benefits outweigh the risks. It is not recommended for use during breastfeeding as both Voglibose and Metformin can pass into breast milk.
Side Effects:
Like all medications, Vogligold M 0.2 can cause side effects, though not everyone experiences them. Some common side effects include:
- Gastrointestinal Issues:
- Nausea
- Diarrhea
- Stomach upset
- Flatulence (gas)
These side effects are often temporary and may improve as the body adjusts to the medication. To reduce the risk of these side effects, it is advisable to take the medication with food.
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Hypoglycemia: While rare, low blood sugar can occur, particularly if the patient is also taking other medications that lower blood sugar levels.
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Lactic Acidosis: Although uncommon, lactic acidosis is a serious condition that can be life-threatening. Symptoms include muscle pain, difficulty breathing, abdominal discomfort, and tiredness. Immediate medical attention is required if these symptoms occur.
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Other Possible Side Effects:
- Weight gain (more common with Metformin)
- Skin rashes
- Headache
Drug Interactions:
Vogligold M 0.2 may interact with other medications, which could either reduce its effectiveness or increase the risk of adverse effects. Some common drug interactions include:
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Insulin or Other Oral Hypoglycemics: When taken in combination with insulin or other oral hypoglycemic agents, Vogligold M 0.2 may increase the risk of hypoglycemia.
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Diuretics (Water Pills): Diuretics can increase the risk of dehydration, which may intensify side effects like dizziness or lightheadedness.
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Corticosteroids: The use of corticosteroids may reduce the effectiveness of Voglibose and Metformin in controlling blood glucose levels.
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ACE Inhibitors: These drugs, commonly used to treat high blood pressure, may interact with Vogligold M 0.2 and increase the risk of low blood sugar.
It is important to discuss all medications, including over-the-counter drugs and supplements, with a healthcare provider before starting Vogligold M 0.2.
Price and Availability:
The price of Vogligold M 0.2 can vary depending on the location, pharmacy, and insurance coverage. In India, it is generally priced reasonably, making it an accessible option for most patients managing type 2 diabetes. For accurate pricing, it is best to consult a local pharmacy.
Conclusion:
Vogligold M 0.2 (Voglibose 0.2 mg + Metformin SR 500 mg) offers an effective and well-tolerated option for managing type 2 diabetes. With its dual action of slowing glucose absorption from the gut and improving insulin sensitivity, it helps maintain stable blood sugar levels. As with any medication, it is essential to use Vogligold M 0.2 under the guidance of a healthcare professional to ensure it is appropriate for your condition and to monitor for potential side effects. Through careful management of diet, exercise, and medication, individuals with type 2 diabetes can effectively control their condition and reduce the risk of complications.
About The Author
Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
Call/WhatsApp: 8209542042 , 8824175417
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