FABRICAL ALPHA 0.5 is a highly effective medication designed to address deficiencies in calcium and phosphate metabolism. This prescription medication contains Alfacalcidol, a form of vitamin D used to treat conditions arising from low levels of calcium in the body. Alfacalcidol is particularly beneficial for patients with chronic kidney disease, hypoparathyroidism, and other conditions leading to impaired calcium metabolism. FABRICAL ALPHA 0.5 helps in the proper absorption and utilization of calcium and phosphate, ensuring optimal bone health and function.

Key Benefits:

• Improves Calcium Absorption: FABRICAL ALPHA 0.5 enhances the absorption of calcium from the gastrointestinal tract, crucial for maintaining healthy bones and teeth.
• Regulates Phosphate Levels: By ensuring balanced phosphate levels, this medication helps prevent complications related to phosphate imbalance.
• Supports Bone Health: Essential for the prevention and treatment of bone disorders like osteomalacia and rickets, FABRICAL ALPHA 0.5 strengthens bone density and integrity.
• Aids in Kidney Function: Particularly beneficial for patients with chronic kidney disease, it helps in the management of renal osteodystrophy.
• Manages Hypoparathyroidism: Effective in treating hypoparathyroidism by compensating for the lack of parathyroid hormone, which regulates calcium levels in the blood.

How Does It Work?

Alfacalcidol, the active ingredient in FABRICAL ALPHA 0.5, is a prodrug that is converted in the liver to calcitriol, the active form of vitamin D3. Calcitriol binds to vitamin D receptors in various tissues, particularly in the intestines, bones, and kidneys. This binding enhances the absorption of calcium and phosphate from the intestines, reduces the excretion of calcium by the kidneys, and mobilizes calcium from bones. Together, these actions help maintain adequate calcium and phosphate levels in the bloodstream, essential for healthy bone formation and maintenance.

Directions for Use:

• Dosage: Follow your healthcare provider’s prescription regarding the exact dosage. Typically, the dosage may vary based on the specific condition being treated.
• Administration: FABRICAL ALPHA 0.5 should be taken orally, with or without food, as directed by your healthcare provider.
• Consistency: Take the medication at the same time each day to maintain consistent blood levels of the active ingredient.
• Monitoring: Regular blood tests may be required to monitor calcium and phosphate levels and adjust the dosage accordingly.

Side Effects:

While FABRICAL ALPHA 0.5 is generally well-tolerated, some patients may experience side effects, including:

• Hypercalcemia: Elevated calcium levels in the blood can lead to symptoms such as nausea, vomiting, constipation, and frequent urination.
• Hyperphosphatemia: High phosphate levels may occur, particularly in patients with renal impairment.
• Allergic Reactions: Rarely, some individuals may experience allergic reactions, including rash, itching, or swelling.
• Gastrointestinal Issues: Mild digestive disturbances like stomach pain, diarrhea, or constipation may occur.

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