METROTREX 10 is a potent medication containing Methotrexate, a well-known disease-modifying antirheumatic drug (DMARD). This medication is primarily used to treat various autoimmune diseases and certain types of cancer. Methotrexate works by suppressing the immune system and inhibiting the growth of rapidly dividing cells, providing relief from symptoms and slowing disease progression.

Key Benefits:

• Autoimmune Disease Management: Effective in treating rheumatoid arthritis, psoriasis, and other autoimmune conditions by reducing inflammation and immune system activity.
• Cancer Treatment: Used in the treatment of certain cancers, such as leukemia, breast cancer, and lung cancer, by inhibiting the growth of cancer cells.
• Symptom Relief: Helps alleviate symptoms like joint pain, swelling, and skin lesions in autoimmune conditions.
• Disease Progression Control: Slows down the progression of autoimmune diseases and certain cancers, improving the quality of life for patients.

How Does It Work?

Methotrexate, the active ingredient in METROTREX 10, works by inhibiting the enzyme dihydrofolate reductase. This enzyme is crucial for DNA synthesis and cell replication. By blocking this enzyme, Methotrexate reduces the proliferation of rapidly dividing cells, such as those found in the immune system and certain cancers. This suppression of the immune system helps decrease inflammation and prevent the overactive immune response seen in autoimmune diseases.

Directions for Use:

• Dosage: The typical starting dose for autoimmune diseases is 7.5 to 15 mg per week, which can be adjusted based on patient response and tolerance. For cancer treatment, the dosage varies depending on the type and stage of cancer.
• Administration: METROTREX 10 is usually taken orally, with or without food. Follow your healthcare provider's instructions carefully.
• Frequency: For autoimmune diseases, Methotrexate is typically taken once a week. In cancer treatment, the frequency and dosage depend on the specific treatment regimen prescribed by your oncologist.

Side Effects:

Methotrexate can cause a range of side effects, which can vary depending on the dosage and duration of treatment. Common side effects include:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, and mouth sores.
• Hematologic Effects: Bone marrow suppression, leads to anemia, leukopenia, and thrombocytopenia.
• Hepatotoxicity: Potential liver damage, which requires regular monitoring of liver function tests.
• Pulmonary Effects: Risk of interstitial pneumonitis, presenting as cough or difficulty breathing.
• Other Effects: Fatigue, dizziness, and increased susceptibility to infections.

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