Pirfenoid 400, containing the active ingredient Pirfenidone (400mg), is a medication used primarily for the treatment of idiopathic pulmonary fibrosis (IPF). IPF is a chronic, progressive lung disease characterized by the thickening and scarring of lung tissue, leading to difficulty in breathing and reduced oxygen supply to the bloodstream. Pirfenoid 400 helps to slow the progression of this debilitating condition, improving the quality of life for patients.

Key Benefits:

• Slows Disease Progression: Pirfenoid 400 effectively slows the progression of idiopathic pulmonary fibrosis, helping to preserve lung function and improve survival rates.
• Reduces Inflammation: By reducing inflammation in the lungs, Pirfenidone helps to alleviate symptoms such as persistent coughing and breathlessness.
• Improves Quality of Life: Regular use of Pirfenoid 400 can lead to an improved quality of life for patients suffering from IPF by managing symptoms and slowing disease progression.
• Well-Tolerated: Most patients tolerate Pirfenidone well, making it a viable long-term treatment option.

How Does It Work?

Pirfenidone works through multiple mechanisms to combat the fibrosis and inflammation associated with IPF:

• Anti-Fibrotic Action: Pirfenidone inhibits the production of fibrotic mediators such as TGF-β, which plays a crucial role in the development of fibrosis.
• Anti-Inflammatory Effects: It also reduces the levels of pro-inflammatory cytokines like TNF-α, thereby decreasing lung inflammation.
• Oxidative Stress Reduction: Pirfenidone exhibits antioxidant properties, reducing oxidative stress in lung tissues, which is associated with fibrosis.

Directions for Use:

• Dosage: The typical dosage of Pirfenoid 400 is one tablet taken three times daily with food. This helps to minimize gastrointestinal side effects and enhance absorption.
• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
• Consistency: For optimal results, take Pirfenoid 400 consistently as prescribed by your healthcare provider, even if you start feeling better.

Side Effects:

While Pirfenoid 400 is generally well-tolerated, some patients may experience side effects, including:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, and loss of appetite may occur, particularly when starting treatment.
• Skin Reactions: Rash, photosensitivity, and other skin reactions may develop, especially with sun exposure.
• Fatigue: Some patients may feel tired or fatigued.
• Liver Function: Elevated liver enzymes have been reported, necessitating regular liver function monitoring.

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