PREGABRIAL NT is a potent combination medication designed to address neuropathic pain and associated symptoms. This medication combines Pregabalin (75mg) and Nortriptyline (10mg), offering a synergistic effect to alleviate pain and improve overall nerve function. It is prescribed for individuals experiencing chronic pain conditions due to nerve damage, providing relief and enhancing the quality of life.

Key Benefits:

• Effective Pain Relief: Provides significant relief from neuropathic pain by targeting the pain pathways in the body.
• Improves Sleep Quality: Helps in improving sleep patterns by reducing pain, which often disrupts sleep.
• Enhanced Nerve Function: Promotes better nerve function and reduces the severity of pain signals.
• Reduces Anxiety and Depression: Alleviates symptoms of anxiety and depression associated with chronic pain conditions, improving overall mental well-being.

How It Works:

PREGABRIAL NT works through a dual mechanism to combat neuropathic pain:

• Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of several neurotransmitters, including glutamate, norepinephrine, and substance P, resulting in decreased pain transmission.
• Nortriptyline enhances the levels of norepinephrine and serotonin by inhibiting their reuptake into nerve cells. This action helps modulate the pain signals and provides antidepressant effects, contributing to pain relief.

Directions for Use:

• Dosage: Follow the prescribed dosage by your healthcare provider. It is usually taken once or twice daily, with or without food.
• Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
• Consistency: Take the medication at the same time each day to maintain an even level of the drug in your body.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it's near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Side Effects:

While PREGABRIAL NT is generally well-tolerated, some individuals may experience side effects, including:

• Dizziness and Drowsiness: Common side effects due to the sedative properties of the ingredients.
• Dry Mouth: A frequent side effect of Nortriptyline.
• Weight Gain: Possible with prolonged use.
• Blurred Vision: Temporary visual disturbances may occur.
• Constipation: Resulting from Nortriptyline’s effect on the digestive system.
• Swelling in Hands or Feet: Pregabalin can cause peripheral edema in some cases.

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