SAVELINER 400 is a specialized pharmaceutical product containing Sevelamer, a phosphate binder used to manage and control high phosphate levels in patients with chronic kidney disease (CKD) on dialysis. By effectively reducing serum phosphate levels, SAVELINER 400 helps prevent the complications associated with hyperphosphatemia, promoting better kidney health and overall well-being.

Key Benefits:

• Reduces Phosphate Levels: Effectively lowers high serum phosphate levels in dialysis patients.
• Prevents Complications: Helps prevent bone disease and calcification of blood vessels and other tissues.
• Improves Quality of Life: Supports overall health and well-being in patients with chronic kidney disease.
• Non-Calcium-Based: Sevelamer is a non-calcium-based phosphate binder, reducing the risk of hypercalcemia.

How Does It Work?

Sevelamer in SAVELINER 400 works by binding to phosphate in the digestive tract. When taken with meals, it attaches to dietary phosphate, preventing its absorption into the bloodstream. This binding action reduces the amount of phosphate that can enter the bloodstream, thereby lowering serum phosphate levels. By managing hyperphosphatemia, Sevelamer helps prevent the associated risks of bone and cardiovascular complications in patients with CKD.

Directions for Use:

• Dosage: The typical starting dose is one to two tablets (400-800mg) taken three times daily with meals. The exact dosage should be determined by your healthcare provider based on your serum phosphate levels.
• Administration: Take the tablets with food, ensuring to swallow them whole with a glass of water. Do not crush, chew, or split the tablets.
• Frequency: Typically, SAVELINER 400 is taken three times a day with meals. Follow your healthcare provider's instructions precisely.

Side Effects:

While SAVELINER 400 is generally well-tolerated, some individuals may experience side effects, including:

• Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain.
• Hypocalcemia: Low calcium levels in the blood, which may require monitoring and management by a healthcare provider.
• Potential Drug Interactions: Sevelamer can interact with other medications, affecting their absorption. Ensure to inform your healthcare provider about all medications you are taking.

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