SILODOSIA M 25 KIT is a specially formulated combipack containing Mirabegron Extended-Release 25 mg and Silodosin 8 mg. This combination is designed to address urinary and bladder issues by leveraging the unique properties of each component. Ideal for patients needing dual-action treatment for overactive bladder and benign prostatic hyperplasia, this kit offers a comprehensive solution to improve urinary flow and reduce bladder overactivity.

Key Benefits:

• Improved Urinary Flow: Silodosin helps in relaxing the prostate muscles and bladder neck, facilitating a smoother urinary flow.
• Reduced Urgency: Mirabegron decreases bladder muscle spasms, thereby reducing the sudden urge to urinate.
• Enhanced Bladder Control: The combination of both ingredients aids in better management of bladder and prostate symptoms.
• Convenient Dosage: With the extended-release formulation of Mirabegron, patients experience prolonged relief with a single dose.
• Dual Action: Addresses both overactive bladder and benign prostatic hyperplasia, providing comprehensive management of urinary symptoms.

How Does It Work?

Mirabegron works by activating beta-3 adrenergic receptors in the bladder, leading to the relaxation of the detrusor muscle and increased bladder capacity. This helps in reducing the frequency and urgency of urination. Silodosin, on the other hand, selectively blocks alpha-1 adrenergic receptors in the prostate and bladder neck, causing relaxation of these muscles. This action facilitates easier urination and improves urinary flow.

Directions for Use:

1. Dosage: Take one Mirabegron Extended-Release 25 mg tablet and one Silodosin 8 mg capsule once daily, preferably at the same time each day.
2. Administration: Swallow the tablets whole with a glass of water. Do not crush or chew the tablets.
3. Food Intake: This can be taken with or without food, but it is best to take it consistently either with or without food to maintain steady absorption levels.
4. Follow the Doctor’s Instructions: Always adhere to the prescribed dosage and regimen as directed by your healthcare provider.

Side Effects:

• Mirabegron: Common side effects may include headache, dizziness, dry mouth, constipation, and urinary tract infection. Rarely, it may cause increased blood pressure or heart rate.
• Silodosin: Side effects can include dizziness, lightheadedness, retrograde ejaculation, and nasal congestion. In rare cases, it may cause severe hypotension or allergic reactions.
• Precautions: Inform your doctor if you have any pre-existing conditions like severe kidney or liver impairment, cardiovascular issues, or if you are taking other medications that might interact with this combination.

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