ST GLIPTIN 25

ST Gliptin 25 is a prescription tablet containing sitagliptin 25 mg. Sitagliptin belongs to the group of diabetes medicines called DPP-4 inhibitors (gliptins).

How it works: After you eat, your gut releases natural hormones called incretins. They signal the pancreas to release insulin when blood sugar rises, and they tell the liver to release less sugar. An enzyme called DPP-4 breaks these hormones down quickly. Sitagliptin blocks DPP-4, so the incretin hormones stay active longer. The result is more insulin when you need it and less sugar release from the liver, mainly around meals.

What makes it different from some older diabetes medicines:

• It works in a glucose-dependent way, so on its own it has a low tendency to cause hypoglycemia (low blood sugar).
• It does not usually cause weight gain.
• It is a simple, once-daily tablet.

Why the 25 mg strength exists: Sitagliptin is cleared mainly by the kidneys. When kidney function falls, the drug builds up, so the dose is lowered. For most adults with normal kidney function, the usual dose is 100 mg once daily, and for moderate kidney impairment it is 50 mg. The 25 mg dose is generally used when kidney function is severely reduced or when a patient is on dialysis. Your doctor selects the strength based on a kidney function test (eGFR), so never choose the strength yourself.

Product at a glance: ST Gliptin 25 is a tablet containing sitagliptin IP 25 mg for adults with type 2 diabetes, taken once daily as prescribed. It is marketed by Steris Healthcare Pvt. Ltd. (Jaipur, India), WHO-GMP and ISO certified, in packs of 10 tablets.

Product Information

Why Is ST Gliptin 25 Important?

India is often called the diabetes capital of the world, and kidney disease is a frequent companion of long-standing diabetes. People living with both conditions face a real challenge: many diabetes medicines are unsuitable or need careful adjustment when the kidneys are weak.

Poorly controlled blood sugar over the years can lead to:

• Kidney damage (diabetic nephropathy), which may progress to dialysis
• Eye damage (retinopathy) and vision loss
• Nerve damage (neuropathy), with numbness, tingling and foot problems
• Heart disease and stroke
• Slow wound healing and infections

For patients with severe kidney impairment, doctors need a diabetes medicine that can be dosed safely. Sitagliptin is one of the gliptins where a dose reduction is available for kidney impairment, which is why a 25 mg strength is useful. With the right dose, it supports steady blood sugar control, and its low tendency to cause hypoglycemia is valuable in people whose kidneys clear insulin and other medicines more slowly.

Why this matters for Indian patients and clinics: diabetologists, nephrologists and physicians managing dialysis patients need dependable, GMP-manufactured options at the right strength, and pharmacies and hospitals need consistent supply.

Key Benefits 

• Improves blood sugar control: helps lower HbA1c and both fasting and after-meal sugar when used with diet and exercise.
• Dose suited to severe kidney impairment: the 25 mg strength matches the reduced dose generally used in this situation, as decided by the doctor.
• Low risk of hypoglycemia when used alone: it acts mainly when blood sugar is high.
• Generally weight-neutral: it does not usually cause weight gain.
• Once-daily, with or without food: easy to fit around meals and dialysis schedules.
• Can be combined with other diabetes medicines: doctors may add it to metformin, a sulfonylurea, pioglitazone or insulin, depending on the patient.
• Made under WHO-GMP and ISO standards: assured manufacturing quality from Steris Healthcare.

Precautions Before Taking 

Tell your doctor before starting if you:

• Have a history of pancreatitis. Sitagliptin has been linked to inflammation of the pancreas. Stop and call your doctor if you get severe, persistent stomach pain that may spread to the back, with or without vomiting.
• Have heart failure or are at risk of it. Some gliptins have been associated with heart failure. Report breathlessness, swelling of the ankles or sudden weight gain.
• Take insulin or a sulfonylurea (such as glimepiride). Combining them can cause low blood sugar, and your doctor may lower their dose.
• Have had an allergic reaction to sitagliptin or any similar medicine. Serious reactions are possible (see side effects).
• Take an ACE inhibitor (for blood pressure). The risk of swelling of the face or throat (angioedema) may be higher.
• Have type 1 diabetes or ketoacidosis. This medicine is not for you.
• Are pregnant, planning pregnancy or breastfeeding. Check with your doctor first.

Possible Side Effects

Many people take sitagliptin without problems. Side effects are usually mild.

Common:

• Runny or stuffy nose and sore throat (upper respiratory tract infection)
• Headache
• Diarrhea or loose stools
• Nausea or stomach upset
• Low blood sugar, mainly when combined with insulin or a sulfonylurea

Less common:

• Constipation
• Swelling of the hands or feet
• Dizziness
• Joint or muscle pain
• Itching or skin rash

Frequently Asked Questions

1. Where can I buy sitagliptin 25 mg online?
Sitagliptin 25 mg can be purchased online through licensed pharmacies in India, subject to prescription requirements. Before purchasing, verify the product name, strength, manufacturer, pack size, expiry date, and authenticity.

2. What is the price of sitagliptin 25 mg?
The price of sitagliptin 25 mg may vary depending on the brand, manufacturer, pack size, pharmacy, and applicable offers or taxes. For the current price, contact the pharmacy or Steris Healthcare directly.

3. Can I order sitagliptin 25 mg online?
Yes, sitagliptin 25 mg may be ordered online through a licensed pharmacy when a valid prescription is provided where required. The pharmacy may verify the prescription before processing the order.

4. Is sitagliptin 25 mg available from Steris Healthcare?
Availability depends on current stock and distribution. To confirm whether sitagliptin 25 mg is currently available from Steris Healthcare, contact the company directly and confirm the product, pack size, and ordering requirements.

5. What is sitagliptin 25 mg used for?
Sitagliptin 25 mg is a DPP-4 inhibitor used to help control blood glucose levels in adults with type 2 diabetes mellitus. The 25 mg strength is commonly used in patients with significantly reduced kidney function, with the exact dose determined by a healthcare professional.

6. What is the composition of sitagliptin 25 mg?
Sitagliptin 25 mg contains sitagliptin 25 mg as the active pharmaceutical ingredient. The inactive ingredients may vary depending on the manufacturer and formulation.

7. Is a prescription required for sitagliptin 25 mg?
Yes. Sitagliptin is a prescription medicine and should be used under the supervision of a qualified healthcare professional. Do not start, stop, or change the dosage without medical advice.

8. How should sitagliptin 25 mg be taken?
Take sitagliptin 25 mg exactly as prescribed by your doctor. It is generally taken once daily, with or without food. The appropriate dose depends on your kidney function and overall treatment plan. Do not change the prescribed dose without consulting your doctor.

9. What should I know before buying sitagliptin 25 mg?
Before buying sitagliptin 25 mg, verify the correct strength, manufacturer, pack size, expiry date, and authenticity. Inform your doctor about kidney problems, pancreatitis, allergies, pregnancy, or other medicines you are taking. If sitagliptin is used with certain diabetes medicines, the risk of low blood sugar may increase.

10. How can I order sitagliptin 25 mg online?
To order sitagliptin 25 mg online, choose a licensed pharmacy, provide a valid prescription when requested, verify the product and pack details, and complete the pharmacy's ordering and payment process. For information about availability and ordering from Steris Healthcare, contact the company directly.