TELMISTRUM AZ 8 is a powerful medication that combines two potent ingredients, Azelnidipine (8 mg) and Telmisartan (40 mg), to effectively manage hypertension (high blood pressure). This combination therapy is designed to offer a comprehensive approach to controlling blood pressure by utilizing the complementary mechanisms of action of both components. Azelnidipine is a calcium channel blocker, while Telmisartan is an angiotensin II receptor blocker (ARB). Together, they provide a synergistic effect that helps in maintaining optimal blood pressure levels and reducing the risk of cardiovascular complications.

Key Benefits:

1. Effective Blood Pressure Control: TELMISTRUM AZ 8 effectively reduces blood pressure by combining the vasodilatory effects of Azelnidipine and the angiotensin receptor blocking properties of Telmisartan.
2. Reduced Cardiovascular Risk: By maintaining blood pressure within the normal range, this medication helps reduce the risk of heart attacks, strokes, and other cardiovascular events.
3. Improved Vascular Health: The dual-action of Azelnidipine and Telmisartan promotes better vascular health by preventing the narrowing of blood vessels and reducing strain on the heart.
4. Once-Daily Dosage: The convenient once-daily dosage ensures consistent blood pressure control and enhances patient compliance.
5. Minimal Side Effects: The combination of Azelnidipine and Telmisartan is well-tolerated, with minimal side effects compared to monotherapy.

How Does It Work?

TELMISTRUM AZ 8 works through the complementary actions of its two active ingredients:

• Azelnidipine: This calcium channel blocker works by relaxing and widening the blood vessels, allowing blood to flow more easily. It reduces the influx of calcium ions into the vascular smooth muscle cells, leading to vasodilation and a subsequent decrease in blood pressure.

• Telmisartan: As an angiotensin II receptor blocker (ARB), Telmisartan prevents the hormone angiotensin II from binding to its receptors on blood vessels. This action prevents vasoconstriction (narrowing of blood vessels), reduces aldosterone secretion, and promotes the excretion of sodium and water. These effects collectively contribute to lower blood pressure.

The combination of these mechanisms ensures a comprehensive approach to managing hypertension, addressing different pathways that contribute to elevated blood pressure.

Directions for Use:

• Dosage: Take one tablet of TELMISTRUM AZ 8 daily, preferably at the same time each day, with or without food.
• Swallow Whole: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
• Consistency: For optimal results, take the medication consistently every day as prescribed by your healthcare provider.
• Follow Medical Advice: Always follow the dosage instructions provided by your healthcare professional. Do not alter the dose or frequency without consulting your doctor.

Side Effects:

While TELMISTRUM AZ 8 is generally well-tolerated, some individuals may experience mild side effects. Common side effects include:

• Dizziness or Lightheadedness: These may occur as your body adjusts to the medication. To reduce the risk of dizziness, rise slowly from sitting or lying positions.
• Headache: Some patients may experience headaches, which are usually mild and temporary.
• Fatigue: A feeling of tiredness or fatigue may occur in some individuals.
• Gastrointestinal Issues: Mild stomach discomfort, nausea, or diarrhea may be experienced by a few patients.
• Flushing: A sensation of warmth or redness, particularly in the face, neck, or chest.

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