VALPOTREAT CR 500 is a controlled-release medication containing Sodium Valproate 500 mg. It is primarily used in the management of epilepsy and other seizure disorders. This formulation ensures a steady release of the medication, providing consistent therapeutic effects and minimizing fluctuations in blood levels.

Key Benefits:

• Seizure Control: Effective in controlling a variety of seizure types, including generalized and partial seizures.
• Mood Stabilization: This can help stabilize mood swings, making it beneficial for patients with bipolar disorder.
• Controlled Release: The CR (Controlled Release) formulation ensures a steady release of medication, improving adherence and reducing the frequency of dosing.
• Reduced Side Effects: By maintaining stable blood levels, the controlled-release mechanism helps minimize side effects associated with peak concentrations of the drug.

How Does It Work?

Sodium Valproate works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that inhibits nerve transmission, which helps to stabilize electrical activity in the brain and prevent seizures. Additionally, Sodium Valproate affects ion channels and other neurotransmitter systems, contributing to its anticonvulsant and mood-stabilizing effects.

Directions for Use:

1. Dosage: Follow your doctor’s prescription regarding the dosage and frequency. Do not adjust the dose without consulting your healthcare provider.
2. Administration: Take the tablet whole with a glass of water. Do not crush or chew the tablet, as this can interfere with the controlled-release mechanism.
3. Timing: It is usually recommended to take the medication at the same time each day to maintain consistent blood levels.
4. Food: This can be taken with or without food, but try to take it the same way each time for consistency.

Side Effects:

• Common Side Effects: Nausea, vomiting, dizziness, drowsiness, hair loss, and weight gain.
• Serious Side Effects: Liver toxicity, pancreatitis, severe allergic reactions, and blood disorders. Seek medical attention if you experience symptoms such as jaundice (yellowing of the skin or eyes), severe abdominal pain, unexplained bruising or bleeding, or swelling of the face, lips, or tongue.
• Precautions: Regular monitoring of liver function and blood counts is recommended. Inform your doctor of any other medications you are taking to avoid potential interactions.

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