Vildagliptin, marketed under the brand name VILDIABATE 50, is an oral medication primarily used to manage type 2 diabetes mellitus. It belongs to the class of drugs known as DPP-4 inhibitors, which help regulate blood sugar levels.

How Does It Work

• Increases Insulin Production: Vildagliptin works by inhibiting the enzyme DPP-4, which leads to an increase in insulin secretion in response to meals.
• Decreases Glucagon Release: It reduces the amount of glucose produced by the liver by decreasing the hormone glucagon.
• Improves Blood Sugar Control: By enhancing the body's natural ability to control blood sugar, Vildagliptin helps maintain better glycemic control.

Uses of Vildagliptin

• Type 2 Diabetes Management: Vildagliptin is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes.
• Combination Therapy: Often prescribed in combination with other diabetes medications like Metformin.

What is Vildagliptin

• DPP-4 Inhibitor: It is a dipeptidyl peptidase-4 inhibitor that enhances the levels of incretin hormones.
• Blood Sugar Regulation: Helps in the regulation of blood glucose levels post meals.

Side Effects

• Common Side Effects: Headache, dizziness, and gastrointestinal discomfort.
• Serious Side Effects: Rarely, it may cause severe pancreatitis or allergic reactions.

Safety Information

• Not for Type 1 Diabetes: Vildagliptin is not recommended for patients with type 1 diabetes.
• Liver Function Monitoring: Regular liver function tests are advised during treatment.
• Kidney Function: Dosage adjustments may be necessary for patients with renal impairment.

Metformin and Vildagliptin Combination

• Enhanced Efficacy: Combining Vildagliptin with Metformin, another antidiabetic drug, can provide better blood sugar control.
• Dual Mechanism: While Vildagliptin increases insulin production, Metformin decreases glucose production in the liver.

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