ACOTIAMATE ER 300 - GASTROMED PHARMA: Uses, Dosage, Side Effects, and More information...

Jul 15, 2024

ACOTIAMATE ER 300 

Acotiamide (300mg ER)

"ACOTIAMATE ER 300," containing Acotiamide (300 mg ER), is a medication widely used to manage and treat symptoms associated with functional dyspepsia (FD). Functional dyspepsia, often referred to as non-ulcer dyspepsia, is a chronic disorder of sensation and movement in the upper digestive tract with symptoms including stomach pain, bloating, and nausea. Acotiamide acts primarily by enhancing gastric motility and improving gastric emptying, providing relief from these uncomfortable symptoms.

Composition and Mechanism of Action

Composition

Acotiamide ER 300 is an extended-release formulation containing 300 mg of Acotiamide hydrochloride. This formulation ensures a sustained release of the active ingredient, providing prolonged therapeutic effects and better symptom management.

Mechanism of Action

Acotiamide works by modulating the action of acetylcholine, a neurotransmitter that plays a crucial role in the contraction of stomach muscles. By inhibiting the enzyme acetylcholinesterase, Acotiamide increases the availability of acetylcholine in the gastrointestinal tract. This leads to enhanced gastric motility and improved coordination of stomach muscle contractions, facilitating better gastric emptying and reducing symptoms of bloating and fullness.

Indications and Usage

Indications

Acotiamide ER 300 is primarily indicated for the treatment of functional dyspepsia. Patients experiencing symptoms such as postprandial fullness, early satiety, and upper abdominal pain benefit significantly from this medication. It is especially effective for those whose symptoms are not adequately managed by lifestyle modifications and other treatments.

Usage

The recommended dosage of Acotiamide ER 300 is one tablet taken orally three times daily before meals. It is important to follow the prescribed dosage and schedule to achieve optimal results. Patients should swallow the tablet whole with water and should not crush or chew it to ensure the extended-release mechanism works effectively.

Benefits of Acotiamide ER 300

Symptom Relief

Acotiamide ER 300 provides substantial relief from the bothersome symptoms of functional dyspepsia. Patients report significant improvements in postprandial fullness, bloating, and upper abdominal pain, enhancing their overall quality of life.

Improved Gastric Motility

By enhancing gastric motility, Acotiamide helps in better digestion and prevents the discomfort associated with delayed gastric emptying. This is particularly beneficial for patients who experience nausea and bloating after meals.

Extended-Release Formulation

The extended-release formulation ensures a steady release of the medication over time, providing sustained relief from symptoms. This reduces the need for frequent dosing and helps maintain consistent therapeutic levels in the bloodstream.

Potential Side Effects

Common Side Effects

As with any medication, Acotiamide ER 300 may cause some side effects. Common side effects include:

  • Headache: Some patients may experience mild to moderate headaches.
  • Diarrhea: Increased gastric motility can sometimes lead to diarrhea.
  • Abdominal Pain: While it is used to treat abdominal pain, some patients may experience transient abdominal discomfort.

Serious Side Effects

Although rare, serious side effects can occur. Patients should seek medical attention if they experience:

  • Severe Allergic Reactions: Symptoms may include rash, itching, swelling, severe dizziness, or trouble breathing.
  • Severe Abdominal Pain: Intense abdominal pain that does not subside may require medical evaluation.

Precautions

Patients with known allergies to Acotiamide or any of its components should avoid using this medication. Additionally, it is important to inform the healthcare provider of any other underlying health conditions or ongoing medications to avoid potential drug interactions.

Drug Interactions

Acotiamide ER 300 may interact with other medications, potentially altering its effectiveness or increasing the risk of adverse effects. Patients should inform their healthcare provider about all medications they are taking, including:

  • Anticholinergic Drugs: These can counteract the effects of Acotiamide.
  • Prokinetic Agents: Concurrent use may enhance the gastrointestinal motility effects.
  • Medications Metabolized by CYP3A4: Acotiamide can affect the metabolism of drugs processed by this enzyme.

Special Populations

Pregnancy and Breastfeeding

The safety of Acotiamide ER 300 during pregnancy and breastfeeding has not been well established. Pregnant or breastfeeding women should use this medication only if clearly needed and prescribed by a healthcare provider after evaluating potential risks and benefits.

Elderly Patients

Elderly patients may be more sensitive to the effects of Acotiamide ER 300. Dosage adjustments and careful monitoring may be necessary to avoid potential side effects.

Children and Adolescents

The safety and efficacy of Acotiamide ER 300 in children and adolescents have not been established. It is not recommended for use in this population without specific guidance from a healthcare provider.

Conclusion

Acotiamide ER 300 offers an effective solution for managing symptoms of functional dyspepsia, significantly improving patients' quality of life. Its unique mechanism of action, combined with the benefits of an extended-release formulation, makes it a valuable option for those suffering from chronic digestive discomfort. As with any medication, it is essential to use Acotiamide ER 300 under the guidance of a healthcare provider, adhering to the prescribed dosage and monitoring for any potential side effects. By doing so, patients can achieve optimal symptom relief and enjoy a better quality of life. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology

For further information

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488

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