AMIDRONE 100 - Manage Arrhythmias with Amiodarone (100mg)

Jul 15, 2024

Introduction

Heart rhythm disorders can severely affect the quality of life and increase the risk of stroke, heart failure, or sudden cardiac arrest. One of the most widely used anti-arrhythmic drugs to manage such conditions is the amiodarone 100 mg tablet. Marketed under the brand name AMIDRONE 100, this medication has proven effective in restoring and maintaining a normal heart rhythm.

AMIDRONE 100 contains amiodarone, a powerful antiarrhythmic agent belonging to Class III of the Vaughan-Williams classification. It is prescribed to treat various types of life-threatening ventricular and supraventricular arrhythmias. Its ability to modulate the electrical impulses of the heart makes it an essential drug for cardiologists worldwide.

Let’s explore more about amiodarone 100 mg oral tablet, including its uses, dosage, side effects, and important precautions.

About This Medication

AMIDRONE 100 contains Amiodarone Hydrochloride, an iodine-rich compound known for its ability to prolong the cardiac action potential and refractory period. By altering the conduction pathways in the heart, it helps restore normal sinus rhythm and reduce arrhythmic episodes.

Key Details:

  • Brand Name: AMIDRONE 100

  • Generic Name: Amiodarone Hydrochloride

  • Strength: 100 mg

  • Form: Oral Tablet

  • Class: Antiarrhythmic (Class III)

The amiodarone 100 mg tablet works by blocking abnormal electrical signals in the heart that can cause irregular heartbeats. It affects sodium, potassium, and calcium channels, along with beta-adrenergic receptor blockade, making it a unique and multifaceted medication.

TABLET USES

The primary purpose of AMIDRONE 100 is to manage and treat various types of irregular heart rhythms. Below are the most common amiodarone uses:

1. Ventricular Tachycardia (VT)

This condition involves a rapid heartbeat originating from the ventricles. Amiodarone slows the electrical conduction and stabilizes the heart rhythm.

2. Ventricular Fibrillation (VF)

Amiodarone 100 mg oral tablet is used in emergencies to treat VF, a potentially fatal condition that causes the heart to quiver instead of pumping effectively.

3. Supraventricular Tachycardia (SVT)

It is also prescribed to treat SVT, an arrhythmia that originates above the ventricles and causes rapid heartbeat.

4. Atrial Fibrillation (AF)

This is one of the most common types of irregular heartbeat. AMIDRONE 100 helps convert the rhythm back to normal and maintain it.

5. Atrial Flutter

The tablet helps slow down the abnormal signals and brings stability to the heart rate.

Other amiodarone uses may include prophylaxis of recurrent arrhythmias and post-operative cardiac rhythm disturbances under medical supervision.

DOSAGE

AMIDRONE 100 should be taken strictly as prescribed by a healthcare professional. The dosage may vary depending on the severity of the arrhythmia and the patient’s response.

General Dosage Guidelines:

  • Loading Phase: A higher dose is often prescribed initially to quickly reach therapeutic levels. For instance, 800–1600 mg per day for 1-3 weeks.

  • Maintenance Dose: Once the desired rhythm is achieved, the dose is reduced to a maintenance level, typically 200–400 mg daily.

  • Tapering: Gradual reduction to amiodarone 100 mg tablet may be recommended for long-term control.

Administration Tips:

  • Swallow the tablet whole with water.

  • Take it consistently at the same time daily.

  • It can be taken with or without food.

  • Avoid grapefruit juice, which can affect the medication’s metabolism.

Never self-adjust the dosage or stop taking the medication abruptly, as this can cause life-threatening arrhythmias.

What Are the Possible Side Effects of This Medicine?

Like all medications, amiodarone 100 mg tablet can cause side effects, some of which may require immediate medical attention.

Common Side Effects:

  • Nausea or vomiting

  • Constipation

  • Fatigue

  • Metallic taste

  • Loss of appetite

Serious Side Effects:

  • Pulmonary Toxicity: A rare but serious condition leading to lung damage. Symptoms include shortness of breath, dry cough, and chest pain.

  • Liver Damage: Elevated liver enzymes and jaundice may occur.

  • Thyroid Dysfunction: Due to high iodine content, it can cause hypo- or hyperthyroidism.

  • Vision Problems: Including blurred vision or seeing halos.

  • Skin Sensitivity: Blue-gray discoloration or sun sensitivity.

  • Bradycardia: Excessively slow heartbeat.

If any serious amiodarone side effects appear, seek medical help immediately. Routine blood work, liver function tests, and ECG monitoring are usually recommended for long-term users of amiodarone 100 mg oral tablet.

Frequently Asked Questions (FAQs)

What is the lowest dose of amiodarone?

The lowest standard maintenance dose is typically 100 mg per day, especially for long-term management after achieving rhythm control.

Can I take AMIDRONE 100 with food?

Yes, it can be taken with or without food. However, it is best to take it consistently with regard to meals to maintain even drug levels.

How long can I take amiodarone?

This depends on your medical condition and how well the rhythm is controlled. Long-term therapy is common but requires routine monitoring.

Does amiodarone affect thyroid function?

Yes, amiodarone contains iodine, which can disrupt thyroid function and lead to hypothyroidism or hyperthyroidism.

Is AMIDRONE 100 safe during pregnancy?

It is generally not recommended during pregnancy unless the benefits clearly outweigh the risks. Discuss with your doctor if you are pregnant or planning to conceive.

What should I avoid while taking amiodarone?

Avoid:

  • Grapefruit or grapefruit juice

  • Sunlight or tanning beds (due to skin sensitivity)

  • Alcohol in excess

Can AMIDRONE 100 interact with other drugs?

Yes, it can interact with several medications, including:

  • Blood thinners like warfarin

  • Digoxin

  • Beta-blockers

  • Calcium channel blockers

  • Anti-seizure medications

Always inform your doctor about all current medications.

Final Thoughts

AMIDRONE 100, containing amiodarone 100 mg tablet, is a cornerstone in the management of serious heart rhythm disturbances. Its unique ability to regulate cardiac impulses across multiple channels makes it exceptionally versatile and powerful in controlling arrhythmias.

However, with great efficacy comes the need for cautious use. The long half-life, potential side effects, and drug interactions necessitate strict medical supervision, especially during prolonged treatment.

This Amiodarone Hydrochloride tablet is a lifeline for many suffering from complex cardiac conditions, but it should be approached with care and regular follow-ups. Always follow the dosage instructions, be vigilant about any side effects, and stay informed.

If you're currently prescribed AMIDRONE 100, continue your journey with confidence and awareness. For new patients or caregivers, consult your cardiologist to understand if the amiodarone 100 mg oral tablet is the right option for managing heart rhythm abnormalities.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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