Allopurinol (100mg) & ALLOPURIC 100 Tablet : Dosage, Side Effects, Precautions and warnings.....

May 13, 2024

 

ALLOPURIC 100 

Allopurinol (100mg)

Allopuric 100 emerges as a cornerstone in the management of gout and hyperuricemia, offering individuals relief from the debilitating symptoms and complications associated with these conditions. In this comprehensive guide, we delve into the intricate details of allopurinol (100mg), elucidating its mechanism of action, clinical indications, dosage guidelines, potential side effects, and essential precautions.

Mechanism of Action:
Allopuric 100, containing allopurinol as its active ingredient, exerts its pharmacological effects by inhibiting xanthine oxidase, an enzyme involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid. By reducing the production of uric acid, Allopuric 100 helps lower serum urate levels, thereby preventing the formation of urate crystals and the subsequent inflammatory response associated with gout.

Clinical Indications:
Allopuric 100 is indicated for the treatment of gout, a form of arthritis characterized by sudden and severe attacks of joint pain, swelling, and inflammation, typically affecting the big toe. Additionally, it may be prescribed for the management of hyperuricemia (elevated serum urate levels) associated with conditions such as chronic kidney disease, certain cancers, and certain medications. Its ability to reduce serum urate levels makes it a valuable therapeutic option for individuals with these conditions.

Dosage Guidelines:
The dosage of Allopuric 100 should be individualized based on factors such as the patient's serum urate levels, renal function, and comorbidities. Typically, the recommended starting dose is 100 mg orally once daily, with gradual dose titration based on the patient's serum urate levels and response to treatment. The maintenance dose may range from 100 mg to 800 mg daily, divided into one or more doses. Patients should be advised to stay well-hydrated and to avoid excessive alcohol consumption during treatment with Allopuric 100.

Potential Side Effects:
While Allopuric 100 is generally well-tolerated, it may be associated with certain adverse effects. Additionally, Allopuric 100 may rarely cause hypersensitivity reactions, including skin rash, fever, and eosinophilia. In rare cases, severe cutaneous adverse reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis may occur. Patients should be educated about these potential side effects and instructed to seek medical attention if they experience any concerning symptoms.

Essential Precautions:
Several precautions should be observed while using Allopuric 100. Patients with a history of hypersensitivity reactions to allopurinol or other components of the formulation should avoid using Allopuric 100. Moreover, caution is warranted in patients with impaired renal function, as dosage adjustments may be necessary to prevent drug accumulation and potential toxicity. Regular monitoring of renal function and serum urate levels is recommended during treatment with Allopuric 100.

In conclusion, Allopuric 100 emerges as a valuable pharmacological tool in the management of gout and hyperuricemia, offering individuals relief from the symptoms and complications associated with these conditions. However, its use requires careful consideration of dosage, monitoring for potential side effects, and adherence to essential precautions. By harnessing the therapeutic potential of Allopuric 100 judiciously, healthcare providers can optimize treatment outcomes and improve the quality of life for individuals affected by gout and hyperuricemia.

Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands: gynecology, Pediatrics, Dental care, and Dermatology. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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