AZATHIOPRIME 25. Tablet - Steris Healthcare PVT LTD………

May 20, 2024

AZATHIOPRIME 25

AZATHIOPRIME 25mg

AZATHIOPRIME 25 is a pharmaceutical product containing Azathioprine (25mg), an immunosuppressive medication commonly used to prevent organ rejection in transplant recipients and to treat various autoimmune diseases. By suppressing the immune system, Azathioprine helps manage conditions where the immune system attacks the body's own tissues.

Uses of AZATHIOPRIME 25

Organ Transplantation

  • Prevention of Organ Rejection: AZATHIOPRIME 25 is often prescribed to patients who have undergone organ transplantation, such as kidney, liver, or heart transplants. It helps prevent the immune system from attacking the new organ.
  • Combination Therapy: It is usually used in combination with other immunosuppressants like corticosteroids and cyclosporine to enhance its effectiveness.

Autoimmune Diseases

  • Rheumatoid Arthritis: AZATHIOPRIME 25 is used to manage rheumatoid arthritis by reducing inflammation and slowing disease progression.
  • Inflammatory Bowel Disease: Conditions like Crohn's disease and ulcerative colitis can be treated with AZATHIOPRIME 25 to reduce intestinal inflammation.
  • Other Autoimmune Conditions: It is also effective in treating lupus, myasthenia gravis, and autoimmune hepatitis.

Mechanism of Action

  • Inhibition of DNA Synthesis: Azathioprine works by inhibiting the synthesis of DNA, which is crucial for the proliferation of immune cells. By reducing the number of immune cells, it helps control the immune response.
  • Suppression of Immune Response: By dampening the immune system, AZATHIOPRIME 25 prevents the body from attacking its own tissues or rejecting transplanted organs.

Dosage and Administration

Recommended Dosage

  • The dosage of AZATHIOPRIME 25 varies based on the condition being treated, the patient’s weight, and their response to the medication. For transplant patients, the initial dosage may be higher and gradually reduced to a maintenance dose.
  • For autoimmune diseases, the dosage is typically lower and adjusted according to the patient's response and tolerance.

Administration Guidelines

  • With or Without Food: AZATHIOPRIME 25 can be taken with or without food. However, taking it with food may help reduce gastrointestinal side effects.
  • Consistency: It is crucial to take the medication at the same time each day to maintain consistent blood levels.
  • Regular Monitoring: Patients should have regular blood tests to monitor their blood cell counts and liver function.

Side Effects

Common Side Effects

  • Gastrointestinal Issues: Nausea, vomiting, and diarrhea are common side effects, especially at the start of treatment.
  • Infections: As an immunosuppressant, AZATHIOPRIME 25 increases the risk of infections.
  • Fatigue: Patients may experience tiredness and lack of energy.

Serious Side Effects

  • Bone Marrow Suppression: The medication can cause bone marrow suppression, leading to reduced blood cell counts. Regular blood tests are essential to monitor this.
  • Liver Toxicity: AZATHIOPRIME 25 can cause liver damage, necessitating regular liver function tests.
  • Increased Cancer Risk: Long-term use of immunosuppressants like Azathioprine may increase the risk of certain types of cancer, such as skin cancer and lymphoma.

Precautions and Warnings

Contraindications

  • Allergy to Azathioprine: Patients with a known allergy to Azathioprine should not take this medication.
  • Severe Infections: Those with severe infections should avoid AZATHIOPRIME 25 as it can further suppress the immune system.

Precautions

  • Pregnancy and Breastfeeding: AZATHIOPRIME 25 should be used with caution during pregnancy and breastfeeding. It is essential to discuss potential risks with a healthcare provider.
  • Concurrent Medications: Patients should inform their healthcare provider about all medications they are taking, as AZATHIOPRIME 25 can interact with other drugs.

Drug Interactions

Medications to Avoid

  • Allopurinol: Co-administration with allopurinol can increase the risk of bone marrow suppression.
  • Warfarin: Azathioprine can affect the efficacy of warfarin, necessitating close monitoring of blood clotting parameters.

Monitoring Required

  • Other Immunosuppressants: When used with other immunosuppressive agents, careful monitoring is required to avoid excessive immune suppression.

Patient Management

Lifestyle Modifications

  • Sun Protection: Patients should take precautions to protect their skin from the sun due to the increased risk of skin cancer.
  • Infection Prevention: Good hygiene practices and avoiding contact with sick individuals are crucial to reduce the risk of infections.

Regular Follow-Ups

  • Blood Tests: Regular blood tests are essential to monitor blood cell counts and liver function.
  • Physical Examinations: Routine check-ups with a healthcare provider help detect any potential side effects early.

Conclusion

AZATHIOPRIME 25 is a vital medication in managing organ transplantation and autoimmune diseases. Its immunosuppressive properties help prevent organ rejection and control autoimmune responses, offering significant benefits to patients. However, it is essential to adhere to prescribed dosages, monitor for side effects, and maintain regular communication with healthcare providers to ensure the best possible treatment outcomes. By understanding the uses, side effects, and precautions associated with AZATHIOPRIME 25, patients can manage their conditions more effectively and improve their quality of life. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

CALL/WHATSAPP: 7877551268, 7849827488

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