Baclofen (25mg) & BACLOFINE 25 Tablet - Steris Healthcare PVT LTD………

May 16, 2024

Introduction

BACLOFINE 25 contains Baclofen (25mg), a widely prescribed muscle relaxant and antispastic agent. It is primarily used for managing muscle spasms, stiffness, and rigidity associated with neurological disorders like multiple sclerosis, spinal cord injuries, and cerebral palsy. Baclofen functions by acting on the central nervous system (CNS) to reduce muscle tightness and enhance mobility.

This article provides in-depth details on BACLOFINE 25, including its mechanism of action, uses, dosage, benefits, side effects, precautions, and more.

Key Ingredients

The active ingredient in BACLOFINE 25 is Baclofen (25mg). It works as a gamma-aminobutyric acid (GABA) receptor agonist that affects the spinal cord’s nerve signals to relieve muscle tension and spasticity.

Inactive Ingredients:

  • Microcrystalline cellulose

  • Magnesium stearate

  • Lactose monohydrate

  • Povidone

  • Silicon dioxide

Key Benefits of BACLOFINE 25

1. Reduces Muscle Spasticity

BACLOFINE 25 is effective in reducing involuntary muscle contractions, making movement easier and less painful.

2. Enhances Mobility and Flexibility

By relaxing the muscles, it helps improve range of motion, allowing patients to regain normal movement.

3. Provides Relief from Pain

It alleviates muscle pain and stiffness, enhancing the overall quality of life for patients suffering from neurological disorders.

4. Helps Manage Neurological Disorders

BACLOFINE 25 is primarily used to manage conditions like:

  • Multiple Sclerosis (MS)

  • Spinal Cord Injuries

  • Cerebral Palsy

  • Stroke-induced Muscle Spasticity

5. Reduces Muscle Cramps and Rigidity

It prevents sudden muscle spasms that cause discomfort and immobility.

How Does BACLOFINE 25 Work?

Baclofen is a CNS depressant that acts on GABA receptors in the spinal cord. GABA is a neurotransmitter that inhibits excessive nerve signal transmission, leading to muscle relaxation. By enhancing GABA’s action, BACLOFINE 25:

  • Decreases excessive nerve activity

  • Reduces muscle spasticity

  • Improves muscle control and coordination

Dosage and Administration

Recommended Dosage

  • Adults: Usually, the starting dose is 5mg three times a day, which can be gradually increased up to 25mg to 100mg per day, depending on the patient’s response.

  • Children: Dosage varies based on weight and medical condition. Pediatric use should be under strict medical supervision.

  • Elderly Patients: Lower doses are recommended to minimize the risk of side effects.

Administration Guidelines

  • Take BACLOFINE 25 with or without food.

  • Swallow the tablet whole with water; do not crush or chew.

  • Maintain a consistent dosing schedule for best results.

  • Do not stop suddenly, as withdrawal symptoms may occur.

Side Effects of BACLOFINE 25

While BACLOFINE 25 is effective, it may cause some side effects, including:

Common Side Effects:

  • Drowsiness

  • Dizziness

  • Weakness or Fatigue

  • Nausea

  • Headache

Serious Side Effects (Seek Medical Attention):

  • Hallucinations or Confusion

  • Seizures

  • Severe Allergic Reactions (Rashes, Swelling, Breathing Difficulty)

  • Uncontrolled Muscle Movements

Precautions and Warnings

1. Avoid Alcohol and CNS Depressants

Alcohol and sedatives can increase drowsiness and dizziness, making daily activities dangerous.

2. Do Not Stop Suddenly

Sudden discontinuation may cause withdrawal symptoms, including anxiety, hallucinations, or seizures.

3. Use in Pregnancy and Breastfeeding

  • Should be used only if necessary during pregnancy.

  • Consult a doctor before using while breastfeeding.

4. Kidney and Liver Disorders

  • Patients with kidney or liver conditions should take BACLOFINE 25 under strict medical supervision.

5. Avoid Driving and Heavy Machinery

Due to possible drowsiness and dizziness, avoid activities requiring mental alertness.

Drug Interactions

BACLOFINE 25 may interact with other medications, including:

1. CNS Depressants:

  • Alcohol, opioids, and benzodiazepines can increase sedation.

2. Antihypertensive Medications:

  • May cause low blood pressure (hypotension).

3. Antidepressants and Antipsychotics:

  • May enhance sedative effects.

4. NSAIDs and Painkillers:

  • Can sometimes lead to stomach irritation when combined.

Always consult a doctor before taking other medications along with BACLOFINE 25.

Overdose and Missed Dose

Overdose Symptoms:

  • Severe drowsiness

  • Weakness

  • Confusion

  • Seizures

  • Breathing difficulties

If an overdose is suspected, seek emergency medical attention immediately.

Missed Dose:

  • If you miss a dose, take it as soon as you remember.

  • If it’s close to the next scheduled dose, skip the missed dose.

  • Do not double dose to make up for a missed one.

Storage and Handling

  • Store BACLOFINE 25 at room temperature (15-30°C).

  • Keep away from moisture and direct sunlight.

  • Keep out of reach of children.

  • Properly dispose of expired or unused medication.

Frequently Asked Questions (FAQs)

1. How long does BACLOFINE 25 take to work?

  • It usually starts working within 1-2 hours of ingestion.

2. Can BACLOFINE 25 be used for back pain?

  • It is primarily prescribed for muscle spasticity, but may sometimes be used for chronic muscle pain.

3. Is BACLOFINE 25 addictive?

  • Long-term use can lead to dependency, so it should be taken only as prescribed.

4. Can I take BACLOFINE 25 for anxiety?

  • It is not FDA-approved for anxiety, but some doctors may prescribe it off-label for anxiety disorders.

5. Does BACLOFINE 25 cause weight gain?

  • Weight changes are rare, but some individuals may experience increased appetite.

Conclusion

BACLOFINE 25 (Baclofen 25mg) is an effective muscle relaxant and antispastic agent that helps patients with neurological disorders, muscle stiffness, and pain. While it provides significant relief, it is essential to use it under medical supervision to avoid potential side effects and withdrawal symptoms. If you experience any adverse reactions, consult your doctor promptly.

Always follow the recommended dosage and take necessary precautions for safe and effective treatment.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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