Baclofen (25mg) & BACLOFINE 25 Tablet - Steris Healthcare PVT LTD………

BACLOFINE 25  & Baclofen (25mg)

Baclofine 25, is a muscle relaxant and antispastic agent that is widely used to manage muscle spasticity. Muscle spasticity is a condition characterized by continuous muscle contraction, leading to stiffness and tightness that can interfere with movement, speech, and daily activities. Baclofen 25mg is a higher dosage formulation aimed at providing effective relief for severe cases of spasticity. This article provides an in-depth look at Baclofen 25mg, including its uses, benefits, dosage, side effects, and precautions.

What is Baclofen?
Baclofen is a gamma-aminobutyric acid (GABA) agonist that works by acting on the central nervous system (CNS). It helps to inhibit the transmission of nerve signals that cause muscle spasticity, thereby reducing stiffness and improving muscle movement. Baclofen is particularly beneficial for conditions such as multiple sclerosis, spinal cord injuries, and cerebral palsy.

Mechanism of Action
Baclofen mimics the action of GABA, a neurotransmitter that inhibits nerve transmission in the brain, thus calming nervous activity. By binding to GABA receptors, Baclofen reduces the overactive nerve signals that lead to muscle spasms and tightness, providing relief and enhancing mobility.

Uses of Baclofine 25
Treating Muscle Spasticity
Baclofine 25mg is primarily prescribed for severe muscle spasticity associated with: Multiple Sclerosis (MS): A disease affecting the CNS, leading to symptoms such as muscle spasms, weakness, and coordination problems.
Spinal Cord Injuries: Baclofen helps alleviate the spasticity resulting from spinal cord injuries.

Baclofine 25mg
Baclofine 25mg tablets are taken orally, with or without food. It is crucial to follow the prescribed dosage and avoid abrupt discontinuation, as sudden withdrawal can lead to severe symptoms like hallucinations and seizures. Titration and Maintenance Dosage adjustments are made carefully to find the optimal balance between efficacy and side effects. Titration involves increasing the dose by 5mg every three days until the desired effect is achieved. Maintenance doses are individualized based on patient needs and responses.

Benefits of Baclofine 25
Enhanced Muscle Control
Baclofen significantly reduces muscle stiffness and spasms, leading to better movement and control. This improvement can greatly enhance the daily functioning and quality of life for individuals with severe spasticity.

Serious Side Effects 

Confusion and Hallucinations: More likely in elderly patients or those with a history of mental health issues.
Seizures: Sudden discontinuation can lead to withdrawal seizures.
Respiratory Depression: High doses can depress the respiratory system, especially in patients with compromised lung function.

Precautions
Patients should inform their healthcare provider about other medications they are taking, as Baclofen can interact with several drugs, including CNS depressants. Alcohol should be avoided while taking Baclofen due to the increased risk of side effects like drowsiness and dizziness.

Special Populations
Pregnancy and Lactation: Baclofen should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so caution is advised for breastfeeding mothers.
Elderly Patients: The elderly may be more susceptible to the sedative effects and may require lower doses.
Drug Interactions
Baclofen can interact with other medications, leading to increased side effects or reduced effectiveness. Notable interactions include:

Conclusion
Baclofen 25mg, marketed as Baclofine 25, is a powerful medication for managing severe muscle spasticity and improving the quality of life for individuals with conditions such as multiple sclerosis, spinal cord injuries, and cerebral palsy. Understanding its uses, benefits, side effects, and precautions allows patients and healthcare providers to optimize treatment and achieve the best possible outcomes. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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