BOSENTIME 125: Improve Exercise Capacity with Bosentan

May 28, 2024

BOSENTIME 125

Bosentan (125mg)

BOSENTIME 125 combination of Bosentan (125mg) is a medication primarily used to treat pulmonary arterial hypertension (PAH). PAH is a serious condition characterized by high blood pressure in the arteries that supply blood to the lungs. This medication helps to improve exercise capacity and delay the progression of PAH, enhancing the overall quality of life for patients.

Uses of Bosentan (125mg) :

  • Pulmonary Arterial Hypertension (PAH): Bosentan is widely prescribed for managing PAH, improving patients' ability to perform physical activities and reducing symptoms.
  • Symptom Relief: The medication alleviates symptoms such as shortness of breath, fatigue, and chest pain associated with PAH.
  • Improving Quality of Life: By managing PAH effectively, Bosentan helps patients maintain a more active and fulfilling lifestyle.

How Bosentan (125mg) Works :

Bosentan is an endothelin receptor antagonist. It works by blocking the effects of endothelin-1, a substance in the blood that causes blood vessels to narrow. By inhibiting this action, Bosentan helps to relax and widen the blood vessels, reducing blood pressure in the lungs and easing the workload on the heart.

Dosage and Administration :

  • Standard Dosage: The typical maintenance dose is 125mg twice daily, following an initial dose of 62.5mg twice daily for the first four weeks.
  • Instructions for Use: Take the tablet whole with water, with or without food. It's important to take Bosentan at the same times each day to maintain an even level in your bloodstream.
  • Missed Dose: If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. 

Side Effects of Bosentan (125mg) :

  • Common Side Effects: These include headache, flushing, nasal congestion, and dizziness.
  • Serious Side Effects: Rare but serious side effects can include liver damage, anemia, and hypotension (low blood pressure).
  • Managing Side Effects: Regular monitoring of liver function and blood counts is recommended. 

Precautions and Warnings :

  • Liver Function: Bosentan can cause liver damage. Regular blood tests are necessary to monitor liver function during treatment.
  • Pregnancy and Breastfeeding: Bosentan can harm an unborn baby. Women of childbearing age should use effective contraception and avoid pregnancy while taking this medication. Breastfeeding is not recommended.
  • Drug Interactions: Inform your doctor about all medications you are taking, as Bosentan can interact with other drugs, including cyclosporine and glyburide.

Drug Interactions  :

  • Cyclosporine: Combining Bosentan with cyclosporine can increase the risk of side effects.
  • Glyburide: Concurrent use with glyburide can increase the risk of elevated liver enzymes and should be avoided.
  • Other Medications: Bosentan can interact with various medications, including antifungals and HIV medications. 

Storage and Handling :

  • Storage: Store at room temperature, away from direct light and moisture. Keep out of reach of children.
  • Handling: Keep the tablets in their original packaging until ready to use to protect from moisture and contamination.

Conclusion :

Bosentan (125mg), known as BOSENTIME 125, is a crucial medication for managing pulmonary arterial hypertension. By understanding its uses, proper dosage, potential side effects, and necessary precautions, patients can effectively incorporate this medication into their treatment regimen, improving their quality of life and long-term health outcomes.Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

CALL/WHATSAPP: 7877551268, 7849827488

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