Cilostazol (100mg) & CILOSTAZONE 100 Mg : Uses, Dosage, Side Effects Precautons and more

CILOSTAZONE 100 Mg

Cilostazol (100mg)

Cilostazol 100 mg is a medication primarily used to treat intermittent claudication, a condition caused by reduced blood flow to the legs, leading to pain and discomfort while walking. This medication contains CILOSTAZONE 100 Mg, a phosphodiesterase type 3 (PDE3) inhibitor that helps improve blood flow and reduce symptoms. This article provides an in-depth look into CILOSTAZONE 100, covering its uses, dosage, side effects, composition, and more, ensuring a comprehensive understanding of this medication.

Composition

CILOSTAZONE 100 contains:

• Cilostazol: 100 mg

Mechanism of Action

Cilostazol works by inhibiting the enzyme phosphodiesterase type 3 (PDE3). This inhibition leads to an increase in cyclic adenosine monophosphate (cAMP) within blood vessels, resulting in vasodilation and inhibition of platelet aggregation. By widening the blood vessels and preventing blood clots, Cilostazol improves blood flow to the limbs, reducing the pain and discomfort associated with intermittent claudication.

Uses

CILOSTAZONE 100 is prescribed for:

• Treatment of intermittent claudication
• Improvement of walking distance in patients with peripheral arterial disease (PAD)
• Management of symptoms related to poor blood circulation in the legs

Dosage

The dosage of CILOSTAZONE 100 should be individualized based on the patient’s condition, response to treatment, and tolerance. Typically, the recommended starting dose is:

• Adults: 100 mg twice daily, taken 30 minutes before or 2 hours after breakfast and dinner

How to Take CILOSTAZONE 100

• Avoid taking it with meals, as food can increase the absorption and potential side effects.
• Maintain a consistent schedule to ensure stable blood levels.

Side Effects

Like any medication, CILOSTAZONE 100 may cause side effects. Common side effects include:

• Headache
• Diarrhea
• Dizziness
• Palpitations
• Abdominal pain

Serious but rare side effects may include:

• Increased risk of bleeding
• Tachycardia (rapid heartbeat)
• Thrombocytopenia (low platelet count)
• Allergic reactions (rash, itching, swelling)

Precautions and Warnings

• Cardiovascular Risk: Cilostazol is contraindicated in patients with heart failure due to the risk of increased mortality.
• Bleeding Risk: Due to its antiplatelet effect, Cilostazol may increase the risk of bleeding. Use with caution in patients taking anticoagulants or other medications that affect blood clotting.
• Liver and Kidney Function: Monitor liver and kidney function regularly, as Cilostazol is metabolized in the liver and excreted by the kidneys.
• Hypersensitivity: Avoid use in patients with known hypersensitivity to Cilostazol or any component of the formulation.

Interactions

CILOSTAZONE 100 can interact with several medications, potentially altering their effects. Some notable interactions include:

• Anticoagulants: Increased risk of bleeding when used with warfarin, aspirin, or other blood thinners.
• CYP3A4 Inhibitors: Drugs such as ketoconazole and erythromycin can increase Cilostazol levels, enhancing its effects and side effects.
• CYP2C19 Inhibitors: Medications like omeprazole can increase Cilostazol levels and its effects.

Monitoring

Regular monitoring is crucial to ensure the safe and effective use of CILOSTAZONE 100:

• Blood Pressure and Heart Rate: Regular monitoring helps assess the cardiovascular impact of the medication.
• Complete Blood Count (CBC): Periodic assessment of blood counts is necessary to detect thrombocytopenia early.
• Liver and Kidney Function Tests: Regular monitoring helps detect any hepatic or renal impairment early.

Lifestyle and Dietary Recommendations

• Diet: Follow a heart-healthy diet low in saturated fats, cholesterol, and sodium to support overall cardiovascular health.
• Exercise: Engage in regular physical activity to improve blood circulation and enhance the benefits of Cilostazol.
• Hydration: Maintain adequate fluid intake to support overall health.

Conclusion

CILOSTAZONE 100, containing Cilostazol, offers an effective solution for managing intermittent claudication and improving walking distance in patients with peripheral arterial disease.  Always consult with a healthcare provider for personalized advice and monitoring while using this medication. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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