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CILOSTAZONE 50 Mg

Cilostazol (50mg)

CILOSTAZONE 50 is a medication used primarily for the treatment of intermittent claudication, a condition caused by peripheral artery disease (PAD) that results in pain and cramping in the legs due to inadequate blood flow. This guide provides an in-depth look at CILOSTAZONE 50, covering its uses, dosage, side effects, composition, and more to ensure a thorough understanding of this medication.

Composition

CILOSTAZONE 50 contains:

• Cilostazol: 50 mg

Mechanism of Action

Cilostazol works as a phosphodiesterase III inhibitor, which helps to inhibit platelet aggregation and widen blood vessels. By doing so, it increases blood flow to the limbs and reduces symptoms of intermittent claudication. This mechanism not only improves walking distance for patients but also enhances overall blood circulation.

Uses

CILOSTAZONE 50 is prescribed for:

• Management of intermittent claudication due to peripheral artery disease (PAD)
• Improving walking distance and reducing pain during physical activity
• Potentially used as an adjunct therapy in other circulatory disorders

Dosage and Administration

The dosage of CILOSTAZONE 50 should be individualized based on the patient’s condition, response to treatment, and tolerability. Typically, the recommended dose is:

• Cilostazol: 50 mg twice daily, taken 30 minutes before or 2 hours after breakfast and dinner

How to Take CILOSTAZONE 50

• Avoid taking it with meals to enhance absorption.
• Maintain a consistent schedule to ensure stable blood levels of the medication.

Side Effects

Like any medication, CILOSTAZONE 50 may cause side effects. Common side effects include:

• Headache
• Diarrhea
• Dizziness
• Palpitations
• Peripheral edema (swelling of the legs or ankles)
• Abnormal stools

Serious but rare side effects may include:

• Increased risk of bleeding
• Tachycardia (rapid heart rate)
• Heart failure exacerbation in susceptible individuals
• Thrombocytopenia (low platelet count)

Precautions and Warnings

• Heart Failure: Avoid use in patients with severe heart failure as it may exacerbate the condition.
• Bleeding Disorders: Use with caution in patients with a history of bleeding disorders due to an increased risk of bleeding.
• Hypersensitivity: Avoid use in patients with known hypersensitivity to Cilostazol or any component of the formulation.
• Liver and Kidney Function: Regular monitoring of liver and kidney function is recommended as Cilostazol is metabolized by the liver and excreted by the kidneys.

Interactions

CILOSTAZONE 50 can interact with several medications, potentially altering their effects. Some notable interactions include:

• Anticoagulants and Antiplatelets: Increased risk of bleeding when used concomitantly with medications such as warfarin, aspirin, or clopidogrel.
• CYP3A4 and CYP2C19 Inhibitors: Drugs such as ketoconazole and omeprazole may increase the concentration of Cilostazol in the blood, necessitating dose adjustments.
• Grapefruit Juice: May increase the levels of Cilostazol and should be avoided.

Monitoring

Regular monitoring is crucial to ensure the safe and effective use of CILOSTAZONE 50:

• Blood Pressure and Heart Rate: Regular monitoring helps assess the cardiovascular effects of the medication.
• Complete Blood Count (CBC): Periodic assessment to monitor for thrombocytopenia.
• Liver and Kidney Function Tests: To detect any potential hepatic or renal dysfunction early.

Lifestyle and Dietary Recommendations

• Diet: Follow a balanced diet rich in fruits, vegetables, and whole grains. Avoid high-fat meals that can affect the absorption of Cilostazol.
• Exercise: Engage in regular physical activity, such as walking, to improve symptoms of intermittent claudication.
• Hydration: Maintain adequate fluid intake to support overall health and circulation.

Conclusion

CILOSTAZONE 50, containing Cilostazol, offers an effective solution for managing intermittent claudication by improving blood flow and reducing symptoms. Always consult with a healthcare provider for personalized advice and monitoring while using this medication. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

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