Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream

Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream is a powerful triple-action topical medication widely prescribed to treat various fungal, bacterial, and inflammatory skin conditions. This combination formulation offers rapid relief from itching, redness, scaling, and skin discomfort associated with infections and allergic reactions.

Let’s explore how each active ingredient contributes to its effectiveness, along with its uses, application, and safety.

What is Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream?

Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream is a dermatologist-recommended combination therapy formulated to treat mixed skin infections. It blends three potent agents:

• Clobetasol Propionate – a corticosteroid that reduces skin inflammation.

• Neomycin Sulphate – an antibiotic that kills harmful bacteria.

• Miconazole Nitrate – an antifungal agent that targets yeast and fungal infections.
   

The synergistic effect of these ingredients provides comprehensive protection against multiple skin issues, especially where a mixed infection (fungal + bacterial + inflammation) is present.

Key Ingredients and Their Mechanism

1. Clobetasol Propionate

Clobetasol Propionate is a high-potency topical corticosteroid that works by inhibiting the production of inflammatory chemicals in the skin. It reduces symptoms such as redness, swelling, and itching.

2. Neomycin Sulphate

Neomycin Sulphate is a broad-spectrum antibiotic effective against gram-positive and gram-negative bacteria. It prevents bacterial growth by interfering with protein synthesis in microbial cells.

3. Miconazole Nitrate

Miconazole Nitrate is an imidazole antifungal agent. It acts by disrupting the fungal cell membrane, leading to leakage and death of the fungal cells. It is particularly effective against Candida and dermatophytes.

Common Uses of Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream

This cream is generally prescribed for the treatment of:

• Fungal infections (like ringworm, athlete’s foot, jock itch)

• Bacterial skin infections

• Eczema with secondary infection

• Inflamed skin rashes with fungal and bacterial involvement

• Seborrheic dermatitis

• Intertrigo

Its wide action spectrum makes it suitable for skin conditions that are not purely fungal or bacterial, but rather a combination of both, often with inflammation.

How to Use Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream

• Clean and dry the affected area before application.

• Apply a thin layer of the cream over the infected area.

• Rub it gently and allow it to absorb.

• Usually applied 2-3 times daily or as directed by your healthcare provider.

• Do not use under occlusive dressings unless prescribed.
   

Always follow the prescription for dosage and duration to avoid side effects or resistance.

Benefits of Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream

• Triple-action therapy – Combines anti-inflammatory, antifungal, and antibacterial properties.

• Quick relief from itching, swelling, and infection.

• Prevents recurrence when used as prescribed.

• Suitable for various skin types and age groups (with caution).

Precautions While Using This Combination Cream

• Avoid applying near eyes, mouth, or open wounds.

• Not recommended for long-term use, especially on sensitive skin areas like the face or groin.

• Not to be used in children below 12 years unless prescribed.

• If irritation, burning, or allergic reaction occurs, discontinue and consult your physician.
   

Side Effects of Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream

While generally safe when used correctly, possible side effects may include:

• Skin thinning or dryness

• Local irritation or burning sensation

• Allergic contact dermatitis

• Risk of antibiotic resistance with prolonged use
   

Always use under medical supervision, especially for long durations.

Storage Instructions

• Store in a cool, dry place, away from sunlight and moisture.

• Keep out of reach of children.

• Do not freeze the cream.

Who Should Avoid Using This Cream?

• People allergic to Clobetasol, Neomycin, or Miconazole

• Patients with viral skin infections (like herpes or chickenpox)

• Individuals with tuberculosis of the skin

• Pregnant or breastfeeding women should consult a doctor before use

Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream in India

This combination cream is widely available in India under various brand names by reputed pharmaceutical companies. It is often sold in 15g, 20g, or 30g tubes for ease of use. It is affordable and accessible, making it a first-line treatment option in dermatology clinics and pharmacies.

Why Dermatologists Recommend Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream

Due to its broad-spectrum action and fast relief properties, dermatologists and general physicians frequently prescribe this cream for:

• Mixed bacterial and fungal skin infections

• Inflammatory skin disorders with secondary infection

• Difficult-to-treat eczema or psoriasis-related infections
   

Why Choose Steris Healthcare for Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream?

When it comes to dermatological care, Steris Healthcare stands out as a trusted and quality-focused pharmaceutical brand. Their formulation of Clobetasol Propionate, Neomycin Sulphate & Miconazole Nitrate Cream offers a combination of efficacy, safety, and affordability that sets them apart from other manufacturers in the market.