dabigatran 150 mg caps
Jan 18, 2023
Introduction
DABIGATREX 150 contains Dabigatran Etexilate (150mg), an advanced oral anticoagulant used to prevent blood clot formation and reduce the risk of stroke and systemic embolism. It belongs to a class of medications called direct thrombin inhibitors, which work by blocking thrombin activity, preventing the formation of harmful clots in the bloodstream. This medication is commonly prescribed for individuals with atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism (PE).
Key Ingredients
Dabigatran Etexilate (150mg)
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A prodrug that is converted into its active form, Dabigatran, inside the body.
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Works as a direct thrombin inhibitor, preventing clot formation.
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Provides a predictable anticoagulant effect without requiring routine blood monitoring.
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Used for stroke prevention in patients with non-valvular atrial fibrillation (NVAF).
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Effective in treating DVT and PE, reducing the risk of recurrent clots.
Uses of Dabigatran Etexilate (150mg)
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Prevention of stroke and systemic embolism in patients with atrial fibrillation.
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Treatment and prevention of Deep Vein Thrombosis (DVT), a condition where blood clots form in the veins of the legs.
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Treatment and prevention of Pulmonary Embolism (PE), a condition where clots travel to the lungs and cause severe complications.
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Prevention of blood clots after hip or knee replacement surgery.
Key Benefits
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Highly effective in preventing stroke in patients with atrial fibrillation.
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No routine blood tests required, unlike traditional anticoagulants such as warfarin.
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Rapid onset of action, providing quick protection against clot formation.
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Lower risk of major bleeding complications compared to older blood thinners.
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Convenient oral dosing, eliminating the need for injections.
How Does Dabigatran Etexilate Work?
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Dabigatran Etexilate is a prodrug that gets converted into its active form, Dabigatran, inside the body.
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Once activated, Dabigatran directly inhibits thrombin, an enzyme responsible for converting fibrinogen into fibrin, which is essential for blood clot formation.
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By blocking thrombin activity, it prevents the formation of new clots and stops existing clots from growing.
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This mechanism makes it highly effective in preventing stroke, embolism, and thrombosis-related complications.
Dosage and Administration
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The typical dose of DABIGATREX 150 is one capsule twice daily.
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It should be taken with or without food, as advised by a healthcare provider.
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Swallow the capsule whole, without crushing, breaking, or chewing.
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If a dose is missed, it should be taken as soon as possible, unless it is close to the next scheduled dose.
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Dosage adjustments may be required for individuals with kidney problems or those at risk of bleeding.
Side Effects of Dabigatran Etexilate (150mg)
While DABIGATREX 150 is generally well-tolerated, some patients may experience mild to moderate side effects, including:
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Bleeding complications, such as nosebleeds, gum bleeding, or prolonged bleeding from minor cuts.
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Gastrointestinal symptoms, including indigestion, acid reflux, nausea, and abdominal pain.
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Bruising easily due to reduced blood clotting ability.
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Fatigue or weakness, which may be associated with minor blood loss.
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Allergic reactions, such as skin rashes, itching, or swelling (rare).
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Severe bleeding events, though uncommon, may require urgent medical attention.
Precautions and Warnings
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Patients with kidney disease should consult a doctor before taking DABIGATREX 150, as the drug is eliminated through the kidneys.
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Avoid alcohol consumption, as it may increase the risk of bleeding.
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Do not discontinue the medication abruptly, as stopping Dabigatran Etexilate suddenly may increase the risk of clot formation.
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Inform your doctor about any history of stomach ulcers, recent surgery, or bleeding disorders.
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Pregnant and breastfeeding women should consult their doctor before using this medication.
Drug Interactions
DABIGATREX 150 may interact with other medications, including:
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Aspirin and NSAIDs (e.g., ibuprofen, naproxen) – may increase the risk of bleeding.
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Antiplatelet drugs (e.g., clopidogrel) – may enhance anticoagulant effects.
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Other blood thinners (e.g., warfarin, heparin) – should be avoided unless prescribed by a doctor.
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Proton pump inhibitors (PPIs) (e.g., omeprazole) – may reduce absorption but are sometimes prescribed to minimize stomach irritation.
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Certain antibiotics and antifungal drugs – may alter drug metabolism and effectiveness.
Price of Dabigatran Etexilate (150mg)
The price of DABIGATREX 150 varies depending on the manufacturer, location, and pharmacy. Generally, the cost of Dabigatran Etexilate (150mg) ranges between ₹500 to ₹2000 per pack, depending on the number of capsules included. Patients may find discounts on online pharmacies and bulk purchases.
Storage Instructions
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Store at room temperature (below 30°C) in a dry place, away from moisture and heat.
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Keep the medication in its original blister pack to prevent exposure to air and humidity.
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Keep out of reach of children and pets.
Frequently Asked Questions (FAQs)
1. Can I stop taking DABIGATREX 150 if I feel better?
No, discontinuing Dabigatran Etexilate suddenly may increase the risk of stroke or blood clots. Always follow your doctor’s advice.
2. How long should I take DABIGATREX 150?
The duration of treatment depends on your condition. Some patients may require long-term anticoagulation therapy, while others may take it for a limited period after surgery or clot treatment.
3. What should I do if I miss a dose?
Take the missed dose as soon as possible unless it is close to the next scheduled dose. Never take a double dose to make up for the missed one.
4. Can I take this medication with food?
Yes, DABIGATREX 150 can be taken with or without food, but taking it with food may help reduce stomach discomfort.
5. Is Dabigatran safer than Warfarin?
Dabigatran Etexilate (150mg) offers predictable anticoagulation, does not require routine blood tests, and has a lower risk of certain bleeding complications compared to warfarin.
Conclusion
DABIGATREX 150, containing Dabigatran Etexilate (150mg), is an advanced oral anticoagulant that provides effective stroke prevention, DVT, and PE treatment. Its direct thrombin inhibition mechanism ensures reliable anticoagulation without the need for frequent blood monitoring. With proper usage, precautions, and medical guidance, this medication can significantly reduce the risk of clot-related complications and improve overall cardiovascular health.
About The Author
Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
Call/WhatsApp: 8209542042 , 8824175417
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