DILTIAZONE CD 90: A Comprehensive Guide to Diltiazem Hydrochloride Extended Release 90 mg

Jan 08, 2025

Introduction

Cardiovascular diseases are among the leading causes of morbidity and mortality worldwide. One of the key approaches to managing these conditions involves the use of calcium channel blockers, and Diltiazone CD 90 is a prominent medication in this category. Containing Diltiazem Hydrochloride Extended Release 90 mg, this medication is used primarily for managing hypertension and angina (chest pain). Diltiazem works by relaxing the blood vessels and improving blood flow, reducing the strain on the heart. This article will explore the uses, benefits, dosage instructions, side effects, and more, providing a thorough understanding of Diltiazone CD 90.

What is DILTIAZONE CD 90?

Diltiazone CD 90 is a prescription medication that belongs to the class of drugs known as calcium channel blockers. The extended release formulation (CD) allows for a slow and consistent release of the active ingredient, Diltiazem Hydrochloride. This means that the drug provides a more sustained therapeutic effect with fewer fluctuations in drug levels, leading to improved patient compliance and better control of blood pressure and angina symptoms.

Key Ingredients in DILTIAZONE CD 90

  • Diltiazem Hydrochloride Extended Release 90 mg: This is the active ingredient in Diltiazone CD 90. Diltiazem works by blocking calcium channels in the heart and blood vessels, which helps relax and widen the blood vessels, reducing the workload on the heart and lowering blood pressure.

  • Inactive Ingredients: These include binders, stabilizers, and other excipients that help in the formulation of the tablet, ensuring that the drug is absorbed effectively and that it delivers the intended therapeutic effect.

How DILTIAZONE CD 90 Works

The action of Diltiazone CD 90 revolves around its ability to block the influx of calcium ions into the cells of the heart and blood vessels. Calcium ions are crucial for the contraction of muscles, including the smooth muscles of blood vessels and the heart. By preventing the entry of calcium, Diltiazem reduces the contraction of these muscles, allowing the blood vessels to relax and dilate. This results in:

  1. Lower blood pressure: By dilating the arteries and veins, Diltiazem reduces vascular resistance, helping to lower blood pressure.
  2. Reduced chest pain (angina): Diltiazem improves blood flow to the heart, thus reducing the occurrence of angina.
  3. Slowed heart rate: It has a mild effect on the heart rate, slowing it down and improving the heart’s efficiency.

Uses of DILTIAZONE CD 90

Diltiazone CD 90 is primarily prescribed for the following medical conditions:

1. Hypertension (High Blood Pressure)

Diltiazem Hydrochloride Extended Release 90 mg is commonly used to treat hypertension. By relaxing the blood vessels, Diltiazem reduces the resistance that the heart has to overcome, which in turn lowers blood pressure. Effective management of high blood pressure is crucial to preventing complications such as stroke, heart attack, and kidney disease.

2. Angina (Chest Pain)

Angina occurs when the heart does not receive enough oxygen-rich blood. Diltiazone CD 90 helps by improving blood flow to the heart and reducing the heart's workload, thus alleviating the symptoms of angina. It helps prevent episodes of chest pain, improving the overall quality of life for patients with chronic stable angina.

3. Supraventricular Tachycardia (SVT)

SVT refers to a condition where the heart beats abnormally fast due to electrical disruptions. Diltiazem can be used to control the rate of the heartbeat in conditions like SVT, helping the heart return to a normal rhythm.

4. Other Cardiovascular Conditions

Diltiazone CD 90 may be used off-label to manage other heart-related issues, including certain types of arrhythmias, where it helps to control the heart’s rhythm by slowing electrical conduction within the heart.

Dosage Instructions for DILTIAZONE CD 90

The usual starting dose of Diltiazone CD 90 is one tablet (90 mg) taken once daily. The extended-release formulation is designed to provide a slow and consistent release of the drug, minimizing fluctuations in blood levels and ensuring continuous therapeutic action throughout the day.

Dosage Adjustments

The dosage may be adjusted based on the individual’s response to the medication and any other underlying health conditions. In some cases, a doctor may recommend increasing the dose to 120 mg or more if needed, especially for managing severe cases of hypertension or angina.

How to Take

  • Take the tablet whole: Do not crush, chew, or break the tablet, as this may interfere with the extended-release properties of the medication.
  • With or without food: Diltiazone CD 90 can be taken with or without food, but it should be taken at the same time each day for consistency.
  • Stay hydrated: Ensure adequate fluid intake when using this medication, as it can sometimes cause dizziness.

Side Effects of DILTIAZONE CD 90

While Diltiazone CD 90 is an effective medication, it can cause side effects in some individuals. The most common side effects include:

Common Side Effects

  • Dizziness or lightheadedness
  • Headache
  • Fatigue
  • Swelling in the ankles or feet
  • Flushing (redness or warmth in the face)

These side effects are usually mild and go away as your body adjusts to the medication. However, if they persist, it is important to consult a healthcare provider.

Serious Side Effects

Although rare, some more serious side effects can occur. Seek medical attention immediately if you experience:

  • Slow heart rate (bradycardia)
  • Severe dizziness or fainting
  • Shortness of breath
  • Chest pain
  • Severe allergic reactions (rash, itching, difficulty breathing)

Precautions and Warnings

Before starting Diltiazone CD 90, it is important to inform your doctor if you have:

  • Heart problems: If you have heart block, sick sinus syndrome, or other heart conditions, special precautions may be needed.
  • Low blood pressure: Diltiazem can lower blood pressure, so it should be used cautiously if you already have hypotension.
  • Kidney or liver disease: If you have kidney or liver impairment, dosage adjustments may be necessary.
  • Pregnancy and breastfeeding: Diltiazone CD 90 should be used during pregnancy only if absolutely necessary, and its safety during breastfeeding has not been established.

Drug Interactions

Diltiazone CD 90 can interact with various medications, potentially affecting its effectiveness or increasing the risk of side effects. Some notable interactions include:

  • Beta-blockers (e.g., metoprolol): When taken with beta-blockers, Diltiazem can excessively lower heart rate and blood pressure.
  • Antifungal medications: Certain antifungal drugs may increase the level of Diltiazem in the blood, leading to potential toxicity.
  • Digoxin: Used for heart problems, when combined with Diltiazem, may increase the risk of digoxin toxicity.
  • Grapefruit: Grapefruit and its juice can increase the concentration of Diltiazem in the bloodstream, increasing the risk of side effects.

Always inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid harmful interactions.

Who Should Use DILTIAZONE CD 90?

Diltiazone CD 90 is prescribed to patients who suffer from:

  1. Hypertension (high blood pressure)
  2. Chronic stable angina (chest pain)
  3. Supraventricular tachycardia (SVT)
  4. Individuals at risk of cardiovascular diseases who require calcium channel blockers for treatment

Conclusion

Diltiazone CD 90, containing Diltiazem Hydrochloride Extended Release 90 mg, is a highly effective medication for managing hypertension, angina, and other heart-related conditions. By blocking calcium channels, it helps to relax blood vessels, lower blood pressure, and improve blood flow to the heart. The extended-release formulation ensures a steady effect throughout the day, making it convenient and effective for patients. While it offers significant benefits, like all medications, Diltiazone CD 90 can cause side effects and interacts with other drugs. Patients should follow the prescribed dosage, report any adverse effects, and consult their healthcare provider for regular checkups. By using Diltiazone CD 90 appropriately, patients can experience better heart health and quality of life. Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma's product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.

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