Empagliflozin 5mg + Metformin 500mg: A Powerful Combination for Diabetes Management

Introduction

GLIEMPAFLOZIN MET 5MG/500MG is a powerful combination medication containing Empagliflozin (5mg) and Metformin Hydrochloride (500mg). This innovative drug is designed to effectively manage type 2 diabetes mellitus by improving glycemic control and reducing the risk of diabetes-related complications. It works through a dual mechanism—enhancing glucose excretion via the kidneys and improving insulin sensitivity.

Key Ingredients

1. Empagliflozin (5mg) – A sodium-glucose co-transporter-2 (SGLT2) inhibitor that reduces blood sugar levels by preventing glucose reabsorption in the kidneys, leading to glucose excretion through urine.

2. Metformin Hydrochloride (500mg) – A biguanide that reduces hepatic glucose production, enhances insulin sensitivity, and improves glucose utilization by muscle cells.

Key Benefits

• Helps in achieving better glycemic control in patients with type 2 diabetes.

• Reduces the risk of cardiovascular complications associated with diabetes.

• Aids in weight management by promoting calorie loss through urine.

• Improves insulin sensitivity, reducing insulin resistance.

• Lowers HbA1c levels, providing long-term diabetes control.

• Enhances renal glucose excretion, helping manage hyperglycemia effectively.

• May help in reducing blood pressure levels due to its mild diuretic effect.

How Does It Work?

GLIEMPAFLOZIN MET 5MG/500MG works through two distinct yet complementary mechanisms:

• Empagliflozin inhibits SGLT2, preventing glucose reabsorption in the kidneys and promoting glucose excretion through urine, leading to lower blood sugar levels.

• Metformin Hydrochloride primarily reduces glucose production in the liver while improving insulin sensitivity, making it easier for the body to utilize glucose efficiently.

Dosage and Administration

• The usual starting dose is one tablet per day, preferably taken with meals to reduce the risk of gastrointestinal side effects.

• Depending on blood sugar levels and patient response, the dosage may be adjusted by a healthcare provider.

• It is essential to adhere to a doctor’s prescription to avoid complications such as hypoglycemia or lactic acidosis.

Side Effects

While GLIEMPAFLOZIN MET 5MG/500MG is generally well-tolerated, some patients may experience:

• Frequent urination due to increased glucose excretion.

• Mild dehydration and dizziness.

• Gastrointestinal discomfort, including nausea, diarrhea, or bloating.

• Hypoglycemia (low blood sugar) when combined with other antidiabetic medications.

• Lactic acidosis (rare but serious), especially in patients with kidney impairment.

• Urinary tract infections (UTIs) and genital fungal infections due to increased sugar excretion in urine.

Precautions and Warnings

• Not suitable for patients with type 1 diabetes or diabetic ketoacidosis.

• Should be used with caution in patients with kidney or liver disease.

• Patients with dehydration risk should maintain adequate fluid intake.

• Not recommended during pregnancy or breastfeeding unless prescribed by a doctor.

• Regular kidney function tests and blood glucose monitoring are advised.

Price and Availability in India

The price of Empagliflozin 5mg and Metformin Hydrochloride 500mg may vary based on the brand, pharmacy, and location. Generally, it is available in strips of 10 to 15 tablets, and the price ranges from INR 200 to INR 500 per strip. Patients can purchase it from leading pharmacies and online medical stores with a valid prescription.

Conclusion

GLIEMPAFLOZIN MET 5MG/500MG is an effective solution for type 2 diabetes management, offering improved blood sugar control with additional cardiovascular and renal benefits. By combining the potent actions of Empagliflozin (5mg) and Metformin Hydrochloride (500mg), this medication supports long-term diabetes control while reducing associated risks. Always consult a healthcare professional before starting or adjusting any diabetes medication regimen.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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