ENTACOVER 1: Entecavir IP (1mg) - Advanced Therapy for Chronic Hepatitis B

Introduction

Entecavir 1 mg is a potent oral antiviral medication primarily used for the treatment of chronic hepatitis B infection in patients with prior resistance to other antiviral agents or those with more advanced liver disease. It is part of the nucleoside analog class of antivirals and works by inhibiting the HBV DNA polymerase enzyme, halting the virus’s replication.ENTACOVER 1, the branded formulation of entecavir 1 mg tablet, is designed for patients requiring a higher strength dose due to lamivudine resistance or HBeAg-negative disease.

Composition of ENTACOVER 1

• Active Ingredient: Entecavir IP 1 mg

• Excipients: Pharmaceutical-grade binders, disintegrants, stabilizers

• Dosage Form: Film-coated oral tablet

Entecavir 1 mg Uses

Here are the key entecavir 1 mg uses:

• Treatment of chronic hepatitis B infection in adults and adolescents

• Treatment of lamivudine-resistant HBV infections

• Used in patients with compensated or decompensated liver disease

• Helps to reduce viral load and improve liver enzyme (ALT/AST) levels

• Prevention of HBV-related complications like cirrhosis, hepatic failure, or hepatocellular carcinoma (HCC)

How Does Tab Entecavir 1 mg Work?

Tab entecavir 1 mg works by:

• Blocking HBV polymerase enzyme

• Inhibiting DNA synthesis and reverse transcription in the virus

• Halting replication and reducing the viral load in the bloodstream

• Supporting liver recovery and minimizing long-term liver damage

This makes entecavir tablets highly effective in controlling HBV infection and protecting liver function.

Dosage and Administration

Typical Dosage:

• 1 mg once daily for:

  • Patients with lamivudine resistance

  • Patients with decompensated liver disease

• 0.5 mg once daily for treatment-naïve patients (use ENTACOVER 0.5)

How to Take:

• Take the entecavir tablet on an empty stomach (at least 2 hours before or after meals)

• Swallow whole with a glass of water

Note: Do not stop taking without medical advice to avoid viral rebound.

Precautions Before Use

Before using ENTACOVER 1, inform your doctor if you:

• Have kidney problems

• Are pregnant or breastfeeding

• Are HIV-positive

• Have a history of lactic acidosis

• Had a liver transplant

Side Effects of Entecavir 1 mg Tablet

Common side effects:

• Fatigue

• Nausea

• Headache

• Dizziness

• Abdominal pain

Rare but serious:

• Lactic acidosis

• Severe hepatomegaly with steatosis

• HBV flare-up upon discontinuation

Drug Interactions

Entecavir 1 mg may interact with:

• Other nucleoside analogues

• HIV medications (avoid monotherapy in co-infected patients)

• Nephrotoxic agents (adjust dose if renal function is impaired)

Always share your full medication list with your healthcare provider.

Storage Instructions

• Store at a temperature below 25°C

• Keep away from moisture and direct sunlight

• Keep out of reach of children

• Do not use expired tablets

FAQs – Frequently Asked Questions

1. What is entecavir 1 mg used for?

It is used for treating chronic hepatitis B, especially in patients resistant to previous treatments or with advanced liver disease.

2. Can I use tab entecavir 1 mg for HIV?

No, entecavir alone is not effective for HIV and may lead to resistance. Use only as prescribed for HBV.

3. How long should I take entecavir tablets?

Often for months to years, depending on your HBV DNA levels and liver function. Follow your doctor’s plan.

4. Is entecavir 1 mg a cure for hepatitis B?

No, it controls the virus but does not eliminate it. Long-term therapy is often needed to maintain suppression.

5. What if I miss a dose of entecavir 1 mg?

Take it as soon as possible. If it’s close to the next dose, skip the missed one. Do not double the dose.

Conclusion

ENTACOVER 1, containing entecavir 1 mg, offers a strong line of defense for patients battling chronic hepatitis B infection, especially those with prior resistance or more serious liver involvement. By effectively suppressing HBV replication and improving liver outcomes, this antiviral tablet remains a cornerstone in hepatitis B management.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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