FENOFIBRON 145 Mg Tablet : Uses, Interactions, Mechanism of Action - DrugBank

Introduction

Cholesterol and triglyceride-related health conditions are among the most common risk factors for heart disease, stroke, and other serious complications. For individuals struggling with high cholesterol or elevated triglyceride levels, medications like FENOFIBRON 145 offer a reliable solution. This pharmaceutical formulation contains Fenofibrate 145 mg, a lipid-lowering agent that has proven efficacy in reducing harmful fats in the blood and supporting overall cardiovascular health.

With the growing need for targeted cholesterol management solutions, FENOFIBRON 145 has emerged as a trusted name among healthcare professionals. In this article, we dive deep into this medication's uses, dosage, side effects, and frequently asked questions, ensuring a complete understanding of the product and its role in lipid regulation.

About This Medication

FENOFIBRON 145 is a prescription drug that contains Fenofibrate 145 mg, an active pharmaceutical ingredient classified under fibrates. Fenofibrate works by modifying lipid metabolism, leading to a significant reduction in triglycerides and low-density lipoprotein (LDL or "bad" cholesterol) while simultaneously increasing high-density lipoprotein (HDL or "good" cholesterol).

Fibrates like Fenofibrate 145 mg tablet are especially helpful in treating mixed dyslipidemia and hypertriglyceridemia, conditions that may not respond well to lifestyle changes alone. The medication targets fatty acid oxidation and enhances the body's ability to break down lipids, thus preventing fat accumulation in blood vessels and organs.

TABLET USES

FENOFIBRON 145 Uses

The tab Fenofibrate 145 mg is primarily prescribed to manage and treat the following conditions:

• Hypertriglyceridemia: Elevated levels of triglycerides in the bloodstream, which increases the risk of pancreatitis.

• Mixed Dyslipidemia: A combination of high triglycerides and cholesterol, typically seen in metabolic syndrome or diabetes.

• Primary Hypercholesterolemia: High levels of total cholesterol and LDL cholesterol.

• Prevention of Cardiovascular Diseases: In patients with existing risk factors like diabetes, obesity, or hypertension.

Additional Uses

• Management of lipid imbalances in diabetic patients.

• Reducing inflammation associated with lipid disorders.

• Supporting statin therapy in selected patients under physician guidance.

DOSAGE

The recommended standard dosage of FENOFIBRON 145 is one tablet containing Fenofibrate 145 mg taken once daily. However, dosage adjustments may be required depending on the patient's condition, response to treatment, and kidney function.

General Dosage Guidelines:

• Adults: One Fenofibrate 145 mg tablet per day with or after meals.

• Geriatric Patients: Dosage may be lowered in older adults due to decreased renal function.

• Renal Impairment: Not recommended or requires close monitoring.

Important Tips:

• Always follow the prescribing physician's instructions.

• Take with food to improve absorption.

• Do not skip or double doses.

What Are the Possible Side Effects of This Medicine?

While FENOFIBRON 145 is generally well-tolerated, like all medications, it can cause certain side effects. Being aware of these reactions can help in early detection and timely medical intervention.

Common Side Effects:

• Headache

• Dizziness

• Nausea

• Abdominal discomfort

• Back pain

Less Common but Serious Side Effects:

• Liver enzyme abnormalities

• Muscle pain or weakness (Myopathy)

• Gallstones

• Pancreatitis

• Skin rashes or itching

If you experience any unusual symptoms such as dark-colored urine, persistent fatigue, yellowing of the skin or eyes (jaundice), or severe muscle pain, consult a doctor immediately.

Frequently Asked Questions (FAQs)

What does fenofibrate do?

Fenofibrate 145 mg helps reduce elevated cholesterol and triglyceride levels in the blood. It works by increasing the natural enzyme activity that breaks down fats in the bloodstream. This action helps reduce the risk of atherosclerosis, heart attack, and stroke.

Is fenofibrate safer than a statin?

Fenofibrate and statins work differently. While statins are more effective at reducing LDL cholesterol, fenofibrate is particularly useful for lowering triglycerides and increasing HDL cholesterol. For certain patients, especially those with high triglycerides and low HDL levels, FENOFIBRON 145 may be a safer and more suitable option. However, it’s essential to consult with a healthcare provider to determine the best treatment plan based on individual health profiles.

What is the best time to take fenofibrate?

The best time to take fenofibrate is with a main meal—preferably breakfast or dinner—to improve absorption. Taking it consistently at the same time each day helps maintain stable drug levels in the blood, enhancing effectiveness.

Does fenofibrate cause erectile dysfunction?

Erectile dysfunction is not a common side effect of Fenofibrate 145 mg. However, any medication that affects blood flow or lipid metabolism may, in rare cases, influence sexual health. If you notice changes in libido or erectile function while using FENOFIBRON 145, speak to your doctor for a comprehensive evaluation.

Can I take FENOFIBRON 145 with other cholesterol-lowering drugs?

Yes, but only under the supervision of your doctor. Fenofibrate 145 mg can be used in combination with statins in select cases. However, the combination can increase the risk of muscle-related side effects, so regular monitoring is essential.

Is this tablet safe for diabetic patients?

Yes. Tab Fenofibrate 145 mg is often used in diabetic patients who have high triglyceride levels. It may also help reduce the risk of diabetic complications related to lipid imbalance. Blood sugar levels should still be monitored during treatment.

Can I drink alcohol while taking FENOFIBRON 145?

Alcohol consumption should be limited while on Fenofibrate 145 mg tablet. Alcohol can interfere with lipid control and increase liver strain, possibly enhancing side effects.

Key Benefits of FENOFIBRON 145

• Significantly lowers triglyceride levels.

• Helps increase good HDL cholesterol.

• Reduces the risk of atherosclerosis and cardiovascular diseases.

• Supports lipid control in metabolic syndrome and diabetes.

• Convenient once-daily dosage.

How FENOFIBRON 145 Works

FENOFIBRON 145 contains Fenofibrate 145 mg, a compound that activates the peroxisome proliferator-activated receptor alpha (PPARα). This receptor plays a key role in lipid metabolism. Once activated, it increases the oxidation of fatty acids and the breakdown of triglycerides, ultimately improving the lipid profile.

Additionally, Fenofibrate improves insulin sensitivity and may reduce inflammation in blood vessels, offering further cardiovascular protection.

Precautions and Warnings

• Not recommended for patients with severe liver or kidney disease.

• Should not be used during pregnancy or breastfeeding unless advised by a physician.

• Avoid in patients with a history of gallbladder disease.

• Regular liver function tests and lipid profiles are necessary during prolonged use.

• Inform your doctor about any other medications or supplements being used to avoid interactions.

Drug Interactions

FENOFIBRON 145 may interact with:

• Statins (e.g., atorvastatin, simvastatin): Increased risk of muscle injury.

• Blood thinners (e.g., warfarin): Enhanced blood-thinning effects.

• Immunosuppressants (e.g., cyclosporine): May impair kidney function.

• Oral antidiabetic drugs: May increase the risk of hypoglycemia.

Always discuss your full medical history and ongoing medications with your doctor before starting Fenofibrate 145 mg.

Storage Instructions

• Store in a cool, dry place away from moisture and sunlight.

• Keep out of reach of children.

• Do not use expired tablets.

Final Thoughts

FENOFIBRON 145, with its active ingredient Fenofibrate 145 mg, stands out as an effective option for managing lipid disorders. Whether used alone or alongside other cholesterol-lowering medications, it offers targeted benefits for reducing triglycerides, increasing HDL levels, and supporting cardiovascular health.

For those dealing with persistent cholesterol or triglyceride imbalances, especially in the context of diabetes or metabolic syndrome, FENOFIBRON 145 can play a critical role in long-term disease prevention.

Like any prescription medicine, it is vital to take FENOFIBRON 145 under the guidance of a healthcare professional and maintain regular monitoring. Along with healthy lifestyle choices, this medication can significantly improve lipid profiles and reduce the risk of life-threatening conditions.

If you’ve been prescribed tab Fenofibrate 145 mg, stay informed, follow your doctor’s advice, and prioritize regular checkups for a healthier future.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW