Glimepride + Metformin

Introduction

SEIZMET G 0.5 is a powerful combination medication containing Glimepiride (0.5mg) and Metformin SR (500mg), formulated to effectively manage Type 2 Diabetes Mellitus. This dual-action therapy helps regulate blood sugar levels by improving insulin sensitivity and stimulating insulin release. It is widely prescribed for patients who require better glycemic control and is known for its sustained-release formulation, ensuring prolonged effectiveness throughout the day.

Diabetes is a chronic condition affecting millions worldwide, requiring strict blood sugar management. SEIZMET G 0.5 is a trusted medication combining Glimepiride (0.5mg) and Metformin SR (500mg) to provide effective blood sugar control. By targeting different mechanisms of action, it ensures better glucose utilization and insulin regulation, reducing the risk of hyperglycemia.

Key Ingredients

Glimepiride (0.5mg)

Glimepiride is a sulfonylurea class medication that works by stimulating the pancreas to release more insulin. This enhances glucose uptake by body cells and reduces blood sugar levels effectively.

Metformin SR (500mg)

Metformin is a biguanide that improves insulin sensitivity, decreases glucose production in the liver, and delays sugar absorption in the intestines. The sustained-release (SR) formulation ensures gradual drug release, reducing side effects such as gastrointestinal discomfort.

Key Benefits of SEIZMET G 0.5

• Effective Glycemic Control: Lowers fasting and postprandial blood glucose levels.

• Dual Mechanism of Action: Enhances insulin secretion and improves glucose utilization.

• Sustained-Release Formula: Ensures prolonged effectiveness and reduces fluctuations in blood sugar levels.

• Reduced Risk of Hypoglycemia: Compared to other sulfonylureas, Glimepiride has a lower risk of causing dangerously low blood sugar.

• Weight-Neutral: Unlike some diabetes medications, it does not contribute to significant weight gain.

• Improves Metabolic Function: Helps lower HbA1c levels and improves overall diabetes management.

How SEIZMET G 0.5 Works

Glimepiride stimulates the pancreatic beta cells to increase insulin secretion, helping the body utilize glucose efficiently. Meanwhile, Metformin SR decreases the liver's glucose production and enhances insulin sensitivity in muscle cells, ensuring better glucose uptake. The sustained-release formulation prevents sudden spikes or drops in blood sugar levels, promoting stable control throughout the day.

Dosage and Administration

• Recommended Dose: One tablet daily or as directed by the physician.

• Timing: Best taken with meals to reduce the risk of gastrointestinal side effects.

• Dosage Adjustment: Based on blood sugar levels and individual response.

• Missed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose. Do not double dose.

Side Effects of SEIZMET G 0.5

Like all medications, SEIZMET G 0.5 may cause some side effects, though they are generally mild and well-tolerated.

Common Side Effects

• Mild Hypoglycemia: Symptoms include dizziness, hunger, sweating, and confusion.

• Nausea and Vomiting

• Diarrhea or Stomach Discomfort

• Mild Weight Gain or Loss

• Headache and Fatigue

Serious Side Effects (Rare)

• Severe Hypoglycemia: If blood sugar levels drop too low, immediate medical attention is required.

• Lactic Acidosis: A rare but serious condition associated with Metformin use.

• Allergic Reactions: Symptoms such as rashes, swelling, or breathing difficulty require urgent medical care.

• Liver or Kidney Dysfunction: Requires monitoring, especially in patients with pre-existing conditions.

Precautions and Warnings

• Not Suitable for Type 1 Diabetes or Diabetic Ketoacidosis.

• Avoid Alcohol Consumption as it increases the risk of lactic acidosis and hypoglycemia.

• Pregnancy and Breastfeeding: Consult a doctor before use.

• Kidney or Liver Disease: Dose adjustments may be necessary under medical supervision.

• Regular Monitoring: Routine blood sugar checks and HbA1c testing are essential for optimal diabetes control.

Drug Interactions

Certain medications may interact with SEIZMET G 0.5, altering its effectiveness.

• Beta-Blockers & Blood Pressure Medications: Can mask symptoms of hypoglycemia.

• NSAIDs & Corticosteroids: May affect blood sugar levels.

• Antibiotics (Fluoroquinolones): Potential risk of altered glucose metabolism.

• Diuretics (Thiazides & Loop Diuretics): Can reduce the efficacy of Metformin.

Lifestyle and Dietary Recommendations

To achieve the best results with SEIZMET G 0.5, incorporating a healthy lifestyle is crucial.

• Balanced Diet: High-fiber, low-sugar meals help regulate blood sugar levels.

• Regular Exercise: Improves insulin sensitivity and promotes overall well-being.

• Hydration: Drink plenty of water to avoid dehydration, especially when taking Metformin.

• Portion Control: Helps prevent blood sugar spikes and weight gain.

• Regular Health Checkups: Routine monitoring ensures effective diabetes management.

Price and Availability in India

The price of SEIZMET G 0.5 varies depending on the manufacturer and location. In India, a strip of 10 tablets typically costs between ₹50 - ₹150, making it an affordable option for diabetes management. It is available in leading pharmacies and online drug stores with a valid prescription.

Conclusion

SEIZMET G 0.5 (Glimepiride 0.5mg + Metformin SR 500mg) is an effective and well-tolerated medication for Type 2 Diabetes Mellitus. Its dual-action formula ensures better blood sugar control, improved insulin sensitivity, and reduced risk of complications. When combined with a healthy lifestyle, regular monitoring, and a balanced diet, this medication plays a significant role in effective diabetes management. Always consult your healthcare provider before starting or modifying your diabetes treatment plan.

Disclaimer: This article is for informational purposes only and should not be considered medical advice. Always consult a doctor for proper diagnosis and treatment.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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