Glisitaptin 50 

Nov 18, 2022

Introduction

GLISITAPTIN M 50/500 is a combination medication designed for the effective management of type 2 diabetes mellitus (T2DM). It contains Sitagliptin Phosphate (50mg) & Metformin HCl (500mg), two well-known anti-diabetic agents that work together to help control blood sugar levels. This medication is recommended for patients who require better glycemic control when diet and exercise alone are insufficient. GLISITAPTIN M 50/500 is an essential part of diabetes management and helps prevent complications associated with high blood sugar, such as heart disease, kidney issues, and nerve damage.

Key Ingredients

1. Sitagliptin Phosphate (50mg)

  • Dipeptidyl Peptidase-4 (DPP-4) inhibitor that increases insulin secretion.

  • Helps regulate blood glucose by enhancing incretin hormones.

  • Reduces post-meal glucose spikes.

  • Lowers fasting blood sugar levels.

2. Metformin HCl (500mg)

  • A biguanide-class medication that reduces glucose production in the liver.

  • Enhances insulin sensitivity, allowing better glucose uptake by muscles.

  • Slows the absorption of sugar in the intestines.

  • Helps in weight management for diabetic patients.

Key Benefits

  • Improves Blood Sugar Control: Regulates glucose levels throughout the day.

  • Dual Mechanism of Action: Enhances insulin production and decreases glucose production.

  • Reduces HbA1c Levels: Helps maintain optimal long-term blood sugar levels.

  • Lowers Risk of Diabetes Complications: Reduces risks of cardiovascular diseases and diabetic neuropathy.

  • Weight-Neutral & Low Hypoglycemia Risk: Less likely to cause weight gain compared to other diabetes medications.

How Does It Work?

GLISITAPTIN M 50/500 combines the glucose-lowering effects of Sitagliptin Phosphate & Metformin HCl to provide effective diabetes control:

  • Sitagliptin Phosphate works by inhibiting DPP-4 enzymes, increasing the levels of incretin hormones (GLP-1 & GIP). These hormones promote insulin release and reduce glucagon secretion, lowering blood sugar.

  • Metformin HCl reduces hepatic glucose production, enhances insulin sensitivity, and delays intestinal glucose absorption, helping to maintain steady blood glucose levels.

  • This combination effectively regulates both fasting and postprandial (after meals) glucose levels.

Directions for Use

  1. Dosage: Take one tablet daily or as prescribed by a doctor.

  2. Timing: Usually taken with meals to improve absorption and minimize side effects.

  3. Swallow whole: Do not crush, chew, or break the tablet.

  4. Follow dietary & lifestyle recommendations: Regular exercise and a balanced diet enhance effectiveness.

  5. Regular blood sugar monitoring is essential for dose adjustments.

Side Effects

While GLISITAPTIN M 50/500 is generally well-tolerated, some individuals may experience mild to moderate side effects:

  • Gastrointestinal issues: Nausea, diarrhea, stomach pain, and bloating.

  • Mild hypoglycemia: Dizziness, sweating, and hunger (rare when taken alone but possible with other diabetes medications).

  • Headache & Fatigue: Temporary effects that usually resolve over time.

  • Vitamin B12 deficiency (long-term use of Metformin).

  • Lactic Acidosis (rare but serious): Symptoms include muscle pain, trouble breathing, and severe fatigue.

Precautions & Warnings

  • Not recommended for patients with kidney or liver disease.

  • Avoid in cases of severe heart failure or metabolic acidosis.

  • Should not be used during pregnancy or breastfeeding without doctor consultation.

  • Limit alcohol consumption, as it may increase the risk of lactic acidosis.

  • Regular kidney function tests are necessary for long-term users.

Price & Availability

The price of GLISITAPTIN M 50/500 varies depending on the brand, manufacturer, and location. Generally, it is available in a price range of ₹200 to ₹800 per strip of 10 tablets. It can be purchased from local pharmacies or online medical stores. Patients are advised to buy from reputable sources to ensure quality and authenticity.

Conclusion

GLISITAPTIN M 50/500 is a highly effective combination therapy for managing type 2 diabetes mellitus. With the powerful blend of Sitagliptin Phosphate & Metformin HCl, it helps achieve better blood sugar control, reduces the risk of complications, and improves overall metabolic health. For the best results, use under medical supervision, follow a healthy lifestyle, and maintain regular blood sugar monitoring. Always consult a doctor before making any changes to your diabetes management plan.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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