Leflunomide (20mg) g

Leflunomide (20mg)

LEFLUNOMILE 

Leflunomide is a medication primarily used in the treatment of rheumatoid arthritis, a chronic autoimmune disorder that causes inflammation and pain in the joints. Here's some key information about leflunomide:

1. Indication: Leflunomide is indicated for the treatment of rheumatoid arthritis to reduce signs and symptoms, inhibit structural damage, and improve physical function.

2. Mechanism of Action: Leflunomide works as a disease-modifying antirheumatic drug (DMARD). Its exact mechanism of action is not fully understood, but it is believed to inhibit dihydroorotate dehydrogenase, an enzyme involved in the production of pyrimidines, which are essential components of DNA and RNA. By inhibiting this enzyme, leflunomide interferes with the proliferation of activated lymphocytes, which are involved in the autoimmune response underlying rheumatoid arthritis.