Levosulpride (75mg SR), Rabeprazole (20mg)``````

Digestive health and mental well-being are closely linked, and many patients experience gastrointestinal discomfort coupled with mood or behavioral disorders. RABISTRUM LS, formulated with  rabeprazole sodium, offers a unique combination therapy designed to address acid-related gastrointestinal disorders and associated neuropsychiatric symptoms.

Levosulpride is a selective dopamine D2/D3 receptor antagonist with prokinetic and antipsychotic properties, helping regulate gastrointestinal motility and mood-related conditions. Rabeprazole, on the other hand, is a proton pump inhibitor (PPI) that reduces gastric acid secretion, providing effective relief from acid reflux, heartburn, and gastritis. Together, this combination offers comprehensive therapy for patients with overlapping gastrointestinal and functional gastrointestinal disorders, improving both physical and mental health.

RABISTRUM LS is particularly prescribed for conditions such as gastroesophageal reflux disease (GERD) with associated functional dyspepsia, functional gastrointestinal disorders, and certain neuropsychiatric gastrointestinal disorders.

Levosulpride 75 mg SR and Rabeprazole 20 mg of Use

Rabeprazole uses is indicated for the treatment of acid-related gastrointestinal disorders with associated neuropsychiatric or functional symptoms.

1. GERD, or gastroesophageal reflux disease

• decreases the production of gastric acid
• relieves epigastric pain, regurgitation, and heartburn.

2. Dyspepsia Functional

• enhances stomach emptying and motility

• reduces nausea, bloating, and pain in the upper abdomen

3. Peptic ulcer disease and gastritis

• Rabeprazole shields the mucosa of the stomach.

• rabeprazole capsules lessens dyspeptic symptoms and promotes motility.

4. Neuropsychiatric Components of Gastrointestinal Disorders

• Functional conditions such as irritable bowel syndrome accompanied with symptoms of depression or anxiety

• Levosulpride enhances gut-brain connection via regulating dopamine-related pathways.

5. Drug-Induced or Postoperative Gastric Dysmotility

• increases the motility of the intestines

• lessens discomfort during surgery or from drugs that affect the stomach

Levosulpride 75 mg SR and Rabeprazole 20 mg of Benefits

1. Dual Action Treatment

• Levosulpride 75 mg SR: Controls neuropsychiatric symptoms and gastrointestinal motility

• Rabeprazole 20 mg: Promptly relieves symptoms by lowering stomach acid production

2. Efficient Acid Management

• treats gastritis, acid reflux, and heartburn

• helps people with injury from acid to recover their stomach mucosa.

3. Enhances Motility of the Stomach

• accelerates the emptying of the stomach

• lessens nausea, fullness, and bloating brought on by delayed stomach emptying

4. Support for Neuropsychiatric Symptoms

• Levosulpride helps lessen gastrointestinal symptoms associated with anxiety or mood.

• promotes the control of the gut-brain axis

5. Prolonged Protection of the Digestive System

• Rabeprazole guards against acid-induced damage and recurrent ulcers.

• In persistent dyspepsia, combined therapy may lower recurrence rates.

6. Easy Single-Dose Treatment

• Long-term release Levosulpride guarantees a steady treatment outcome.

• simplifies the treatment plan to improve adherence

Levosulpride 75 mg SR and Rabeprazole 20 mg of Dosage

Recommended Adult Dosage

• 1 tablet daily, preferably before meals or as directed by a physician

• Sustained-release formulation ensures once-daily dosing

Pediatric Use

• Not recommended for children under 18 years without specialist guidance

Duration of Therapy

• GERD or functional dyspepsia: 4–8 weeks or as advised

• Chronic conditions may require extended treatment under supervision

Administration Instructions

• Swallow the tablet whole with water

• Do not crush, chew, or split the tablet

• Maintain consistent timing each day for optimal effect

Dose Adjustments

• Required in patients with severe liver or kidney impairment

• Elderly patients should use the lowest effective dose to minimize side effects

 rabeprazole capsules price:for price please contact at steris healthcare.

Levosulpride 75 mg SR and Rabeprazole 20 mg of Side Effects

While generally well tolerated, RABISTRUM LS may cause some side effects.

Common Side Effects

• Headache or dizziness

• Mild nausea or abdominal discomfort

• Diarrhea or constipation

Less Common Side Effects

• Sleep disturbances

• Fatigue or drowsiness

• Mild swelling of hands or feet

Rare Side Effects

• Extrapyramidal symptoms (tremors, rigidity) due to Levosulpride

• Allergic reactions (rash, itching, swelling)

• Severe liver enzyme elevation (rare)

Important: Seek medical attention immediately if severe symptoms like persistent vomiting, jaundice, or severe allergic reactions occur.

Precautions and Warnings

Gastrointestinal Precautions

• Avoid use if history of gastric obstruction, severe liver disease, or gastrointestinal bleeding

• Monitor for persistent abdominal pain or black stools

Neurological Precautions

• Levosulpride may cause extrapyramidal symptoms or mood changes

• Report tremors, restlessness, or unusual behavior immediately

Liver and Kidney Safety

• Dose adjustment may be necessary in renal or hepatic impairment

• Periodic monitoring is advised

Pregnancy and Breastfeeding

• Use only if clearly prescribed by a healthcare professional

• Safety during pregnancy and lactation has not been fully established

Drug Interactions

• Avoid combination with other dopamine antagonists, CNS depressants, or strong CYP2C19 inhibitors without medical supervision

Driving and Operating Machinery

• May cause dizziness or drowsiness; avoid driving if affected

Conclusion

RABISTRUM LS, combining Levosulpride 75 mg SR and Rabeprazole 20 mg provides a comprehensive solution for gastrointestinal disorders with neuropsychiatric components. By targeting acid secretion and gastrointestinal motility simultaneously, it effectively relieves heartburn, acid reflux, bloating, nausea, and related symptoms while supporting emotional balance and gut–brain health.

This dual-action therapy is particularly beneficial for patients with functional dyspepsia, GERD, post-operative gastric motility issues, or anxiety-related gastrointestinal discomfort. With its well-tolerated profile, once-daily dosing, and clinically proven efficacy, RABISTRUM LS helps patients achieve relief, improved digestive function, and enhanced quality of life.

F&Q (Frequently Asked Questions)

Can RABISTRUM LS be taken with food?

• Yes, it can be taken with or without food, though taking it before meals is generally preferred for optimal gastric effect.

How long does it take to work?

• Rabeprazole provides symptomatic relief within a few hours, while Levosulpride’s effect on motility and neuropsychiatric symptoms may take several days.

Can it be used long-term?

• Long-term use should be monitored by a physician, especially for prolonged PPI therapy or neuropsychiatric symptoms.

Does it cause drowsiness?

• Some patients may experience mild drowsiness or dizziness due to Levosulpride.

What if a dose is missed?

• Take it as soon as remembered

• If near the next dose, skip the missed dose

• Do not double the dose